diglyceryl sebacate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: diglyceryl sebacate
• 英文别名: Bis(2,3-dihydroxypropanoyl) decanedioate；bis(2,3-dihydroxypropanoyl) decanedioate
• 化学式: C₁₆H₂₆O₁₀
• 分子量: 378.376
• InChiKey: HPXHMXOKEVRUGO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  26
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  168
• 氢给体数：
  4
• 氢受体数：
  10

反应信息

• 作为产物：
  描述：

  癸二酸 、 甘油 、 正丁醇 在 硫酸 作用下， 以 丙酮 为溶剂， 生成 diglyceryl sebacate
  参考文献：
  名称：

  Method for dermatological application

  摘要：

  这是一种用于雀斑、肝斑和痤疮的皮肤应用组合物，其活性成分为0.1至40重量％的含有7至13个碳原子的二羧酸酯，表示为以下通式：##STR1## 其中n = 5-11，R1 =乙基，异丙基，甘油酯或H，R2 =乙基，异丙基，甘油酯或H，其中R1和R2共同为二乙基，二异丙基和二甘油酯，H和乙基，H和异丙基，H和甘油酯。

  公开号：

  US04661519A1

文献信息

• Personal care composition comprising hydrophobic gel
  申请人：The Procter & Gamble Company

  公开号：US20030215477A1

  公开（公告）日：2003-11-20

  Disclosed is a personal care composition comprising by weight: (a) from about 5% to about 35% of a hydrophobic gel comprising: (i) a cholesteryl derivative; (ii) an oil swelling clay material; (iii) a non-volatile liquid oil; and (iv) a polar solvent; and (b) a carrier which is substantially free of water, surfactant, and lecithin; which satisfies the need for a personal care composition having improved physical stability.

  公开了一种个人护理组合物，按重量计包括 (a) 约 5%至约 35%的疏水凝胶，包括 (i) 胆固醇衍生物； (ii) 油膨胀粘土材料 (iii) 非揮發性液體油；及 (iv) 极性溶剂；以及 (b) 一种基本上不含水、表面活性剂和卵磷脂的载体；它能满足对具有更好物理稳定性的个人护理组合物的需求。
• PERSONAL CARE COMPOSITION COMPRISING HYDROPHOBIC GEL
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP1320352A1

  公开（公告）日：2003-06-25
• LIPOPHILIC PERSONAL CARE COMPOSITION
  申请人：The Procter and Gamble Company

  公开号：EP1901813A1

  公开（公告）日：2008-03-26
• Lipophilic personal care composition
  申请人：Masuda Hisatoshi

  公开号：US20070009457A1

  公开（公告）日：2007-01-11

  Disclosed is a lipophilic personal care composition comprising by weight: (a) from about 5% to about 50% of a polyglycerin fatty acid ester having a polyglycerin of 2-15 units and at least 5 fatty acid residues attached thereto, wherein the fatty acid residue has 18 to 24 carbons; (b) from about 5% to about 50% of an N-long chain acyl acidic amino acid ester of sterol having formula (I): XOC(O)—(CH2) n -CH(NHCOR)—C(O)OY  (I) wherein one of X and Y is an ester residue of sterol selected from the group consisting of phytosterol, cholesterol, lanosterol, stigmasterol, its hydrogenates, and its derivatives, and the other is selected from H, an alkyl or alkenyl of 8-30 carbons, and ester residue of monohydric solid alcohol of 12-38 carbons; COR is a long chain acyl group of 8-22 carbons; and n is an integer of 1 or 2; and having a water holding capability of at least 400%, and is liquid at 25° C.; and (c) from about 5% to about 50% of a dimer acid ester.
• US4661519A
  申请人：——

  公开号：US4661519A

  公开（公告）日：1987-04-28