二(2-巯基乙基)琥珀酸酯 | 60642-67-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 二(2-巯基乙基)琥珀酸酯
• 英文名称: bis(2-mercaptoethyl) succinate
• 英文别名: di(2-mercaptoethyl)succinate；bis(2-sulfanylethyl) butanedioate
• CAS: 60642-67-3
• 化学式: C₈H₁₄O₄S₂
• 分子量: 238.329
• InChiKey: KHPRKIZSQDCBGN-UHFFFAOYSA-N

物化性质

• 沸点：
  354.6±32.0 °C(Predicted)
• 密度：
  1.218±0.06 g/cm3(Predicted)
• LogP：
  1.527 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  14
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  54.6
• 氢给体数：
  2
• 氢受体数：
  6

安全信息

• 海关编码：
  2930909090

反应信息

• 作为反应物：
  描述：

  二(2-巯基乙基)琥珀酸酯 、 三氯甲基锡 以 水 为溶剂， 生成 monomethyltin tris[di-(2-mercaptoethyl)succinate]
  参考文献：
  名称：

  WO2008/69904

  摘要：

  公开号：
• 作为产物：
  描述：

  丁二酸酐 、 2-巯基乙醇 在 甲烷磺酸 作用下， 60.0~110.0 ℃ 、4.0 kPa 条件下， 反应 5.5h， 生成 二(2-巯基乙基)琥珀酸酯
  参考文献：
  名称：

  WO2008/69904

  摘要：

  公开号：

文献信息

• MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES
  申请人：Harth Eva M.

  公开号：US20090306335A1

  公开（公告）日：2009-12-10

  In one aspect, the invention relates to polymers, crosslinked polymers, functionalized polymers, nanoparticles, and functionalized nanoparticles and methods of making and using same. In one aspect, the invention relates to degradable polymer and degradable nanoparticles. In one aspect, the invention relates to methods of preparing degradable nanoparticles and, more specifically, methods of controlling particle size during the preparation of degradable nanoparticles. In one aspect, the degradable nanoparticles are useful for complexing, delivering, and releasing payloads, including pharmaceutically active payloads. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  本发明涉及聚合物、交联聚合物、功能化聚合物、纳米颗粒和功能化纳米颗粒以及其制备和使用方法。其中，本发明涉及可降解聚合物和可降解纳米颗粒。本发明还涉及制备可降解纳米颗粒的方法，更具体地说，涉及在制备可降解纳米颗粒过程中控制颗粒大小的方法。在一方面，这些可降解纳米颗粒可用于复合、传递和释放药物活性载荷等方面。本摘要旨在作为搜索特定技术领域的扫描工具，不限制本发明。
• Multifunctional Degradable Nanoparticles with Control over Size and Functionalities
  申请人：Harth Eva M.

  公开号：US20110257343A1

  公开（公告）日：2011-10-20

  In one aspect, the invention relates to polymers, crosslinked polymers, functionalized polymers, nanoparticles, and functionalized nanoparticles and methods of making and using same. In one aspect, the invention relates to degradable polymer and degradable nanoparticles. In one aspect, the invention relates to methods of preparing degradable nanoparticles and, more specifically, methods of controlling particle size during the preparation of degradable nanoparticles. In one aspect, the degradable nanoparticles are useful for complexing, delivering, and releasing payloads, including pharmaceutically active payloads. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  一方面，本发明涉及聚合物、交联聚合物、功能化聚合物、纳米颗粒和功能化纳米颗粒的制备和使用方法。另一方面，本发明涉及可降解聚合物和可降解纳米颗粒。另一方面，本发明涉及制备可降解纳米颗粒的方法，更具体地说，涉及在制备可降解纳米颗粒过程中控制颗粒大小的方法。另一方面，可降解纳米颗粒可用于复合、传递和释放药物活性载荷等用途。本摘要旨在作为搜索特定领域的扫描工具，不限制本发明。
• Organotin compounds and resins or polymers stabilized therewith
  申请人：M & T CHEMICALS, INC.

  公开号：EP0011456B1

  公开（公告）日：1983-09-07
• Thermal stabilizer composition for halogen-containing vinyl polymers
  申请人：Norris Kelly Gene

  公开号：US20070049672A1

  公开（公告）日：2007-03-01

  Stabilizer compositions are used to stabilize halogen-containing vinyl polymers from, for example, degradation and discoloration. The stabilizer compositions comprise a mercaptoester, a reverse mercaptoester, and a Lewis acid.
• Alkyltin sulfanyl diester thiols
  申请人：Krainer Edward

  公开号：US20080132621A1

  公开（公告）日：2008-06-05

  Disclosed herein are compounds of the formula: (R) x —Sn—(R′) 4-x wherein: R is alkyl; R′ is a moiety selected from the group consisting of: w is 0 or 1; x is 1 or 2; y is 1, 2, 3, or 4; and Z is a linear, branched, cyclic, or aromatic hydrocarbon. These compounds are excellent stabilizers for halogen-containing resins, such as PVC.