3-nitro-4-pentyl-benzoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-nitro-4-pentyl-benzoic acid
• 英文别名: 3-Nitro-4-pentyl-benzoesaeure；3-nitro-4-pentylbenzoic acid
• 化学式: C₁₂H₁₅NO₄
• 分子量: 237.255
• InChiKey: JYLIATWMBAGNKL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  83.1
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-nitro-4-pentyl-benzoic acid 在 5%-palladium/activated carbon 、 N,N-二甲基甲酰胺 草酰氯 、 氢气 作用下， 以 乙醇 、 二氯甲烷 、 水 为溶剂， 20.0~100.0 ℃ 、101.33 kPa 条件下， 反应 30.0h， 生成 ethyl 3-dimethylamino-4-pentylbenzoate
  参考文献：
  名称：

  AMINOPYRIDINE COMPOUND

  摘要：

  本发明涉及一种由以下公式（I）表示的化合物或其药学上可接受的盐，含有该化合物的医药组合物，以及用于治疗或预防呼吸道疾病或青光眼的医药组合物。

  公开号：

  US20120259123A1
• 作为产物：
  描述：

  4-正戊基苯甲酸 在 硝酸 作用下， 生成 3-nitro-4-pentyl-benzoic acid
  参考文献：
  名称：

  New mass loss kinetic model for thermal decomposition of biomass

  摘要：

  Based on non-isothermal experimental results for eight Chinese biomass species, a new kinetic model, named as the "pseudo bi-component separate-stage model (PBSM)", is developed in this note to describe the mass loss behavior of biomass thermal decomposition. This model gains an advantage over the commonly used "pseudo single-component overall model (PSOM)" and "pseudo multi-component overall model (PMOM)". By means of integral analysis it is indicated that the new model is suitable to describe the mass loss kinetics of wood and leaf samples under relatively low heating rates (e.g. 10 degreesC/min, used in this work).

  DOI：

  10.1007/bf03183398

文献信息

• [EN] DIARYL THIOETHERS, COMPOSITIONS AND USES THEREOF<br/>[FR] THIOETHERS DE DIARYLE, COMPOSITIONS ET UTILISATIONS DE CES DERNIERES
  申请人：SEPRACOR INC

  公开号：WO2000056707A1

  公开（公告）日：2000-09-28

  The present invention relates to diaryl thioethers, including substituted diphenyl thioethers. Furthermore, the present invention relates to the use of the aforementioned compounds as ligands for cellular receptors, including adenosine and G-protein-coupled receptors. In certain embodiments, the compounds of the present invention are selective ligands, e.g., antagonists or agonists, for a particular family or subtype of adenosine or G-protein-coupled receptor. Additionally, the present invention relates to pharmaceutical preparations comprising the ligands, and their use as medicaments in the treatment of diseases deriving, at least in part, from cellular pathways incorporating adenosine or G-protein-coupled receptors.
• AMINOPYRIDINE COMPOUND
  申请人：Iwamura Ryo

  公开号：US20120259123A1

  公开（公告）日：2012-10-11

  The present invention relates to a compound represented by the formula (I): or a pharmaceutically acceptable salt thereof, a medical composition containing the same, and a medical composition for the treatment or prophylaxis of respiratory diseases or glaucoma.

  本发明涉及一种由以下公式（I）表示的化合物或其药学上可接受的盐，含有该化合物的医药组合物，以及用于治疗或预防呼吸道疾病或青光眼的医药组合物。
• New mass loss kinetic model for thermal decomposition of biomass
  作者：Naian Liu、Weicheng Fan、R. Dobashi、Qizhao Lin

  DOI：10.1007/bf03183398

  日期：2001.8

  Based on non-isothermal experimental results for eight Chinese biomass species, a new kinetic model, named as the "pseudo bi-component separate-stage model (PBSM)", is developed in this note to describe the mass loss behavior of biomass thermal decomposition. This model gains an advantage over the commonly used "pseudo single-component overall model (PSOM)" and "pseudo multi-component overall model (PMOM)". By means of integral analysis it is indicated that the new model is suitable to describe the mass loss kinetics of wood and leaf samples under relatively low heating rates (e.g. 10 degreesC/min, used in this work).