1,3-dithiolan-2-ylidene-methyl-(trimethylsilylmethyl)ammonium trifluoromethanesulfonate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: 1,3-dithiolan-2-ylidene-methyl-(trimethylsilylmethyl)ammonium trifluoromethanesulfonate
• 英文别名: 1,3-Dithiolan-2-ylidene-methyl-(trimethylsilylmethyl)azanium;trifluoromethanesulfonate
• 化学式: CF₃O₃S*C₈H₁₈NS₂Si
• 分子量: 369.526
• InChiKey: KBPULUOHEJJNCM-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  2.39
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  119
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  马来酸二甲酯 、 1,3-dithiolan-2-ylidene-methyl-(trimethylsilylmethyl)ammonium trifluoromethanesulfonate 在 cesium fluoride 作用下， 以 乙腈 为溶剂， 以80%的产率得到
  参考文献：
  名称：

  Dithiolane-isocyanate imminium methylides: A rapid stereoselective entry into γ-lactams

  摘要：

  Methods have been developed for the generation and trapping of dithiolane-isocyanate imminium methylides which are a new type of azomethine methylide-derived 1,3-dipole. These species add efficiently and stereoselectively to electron deficient olefins yielding novel dithiolane-protected gamma-lactans which can be efficiently deprotected to yield to corresponding lactam systems.

  DOI：

  10.1016/0040-4039(95)01998-w
• 作为产物：
  描述：

  2-Methylimino-1,3-dithiolan 、 (三甲基硅基)甲基三氟甲烷磺酸酯 以 二氯甲烷 为溶剂， 以100%的产率得到1,3-dithiolan-2-ylidene-methyl-(trimethylsilylmethyl)ammonium trifluoromethanesulfonate
  参考文献：
  名称：

  Dithiolane-isocyanate imminium methylides: A rapid stereoselective entry into γ-lactams

  摘要：

  Methods have been developed for the generation and trapping of dithiolane-isocyanate imminium methylides which are a new type of azomethine methylide-derived 1,3-dipole. These species add efficiently and stereoselectively to electron deficient olefins yielding novel dithiolane-protected gamma-lactans which can be efficiently deprotected to yield to corresponding lactam systems.

  DOI：

  10.1016/0040-4039(95)01998-w

文献信息

• [EN] HERBICIDAL COMPOSITIONS<br/>[FR] COMPOSITIONS HERBICIDES
  申请人：SYNGENTA CROP PROTECTION AG

  公开号：WO2022033893A1

  公开（公告）日：2022-02-17

  The present invention relates to the use of herbicidal substituted phenyl-pyridazine-diones and substituted phenyl-pyridazinone derivatives of formula (I), in combination with herbicidal pyrazolo-lactam-carboxamides of formula (II) to control undesirable plant growth, in controlling weeds, including broad-leaved and/or narrow-leaved, monocotyledonous and/or dicotyledonous weeds, in crops of useful plants.

  本发明涉及使用式(I)的除草取代苯基吡啶二酮和取代苯基吡啶酮衍生物，与式(II)的除草吡唑咪唑内酰胺结合，用于控制不良植物生长，在有用植物作物中控制杂草，包括宽叶和/或窄叶、单子叶和/或双子叶杂草。
• [EN] HERBICIDAL COMPOUNDS<br/>[FR] COMPOSÉS HERBICIDES
  申请人：SYNGENTA CROP PROTECTION AG

  公开号：WO2022029019A1

  公开（公告）日：2022-02-10

  The present invention relates novel di- and tri-substituted pyrazolo-lactam/thiolactam-carboxamide compounds, methods for their production, and intermediates for use in such methods. The invention further extends to herbicidal compositions comprising such derivatives, as well as to the use of such compounds and compositions in controlling undesirable plant growth: in particular, the use in controlling weeds in crops of useful plants.

  本发明涉及新型的二取代和三取代的吡唑烷酮/硫代烷酮-羧酰胺化合物、其生产方法以及用于这些方法的中间体。本发明进一步扩展到包括这些衍生物的除草剂组合物，以及在控制不良植物生长方面使用这些化合物和组合物：特别是在控制有用植物作物中的杂草方面的使用。
• First Highly Regio- and Diastereoselective [3+2] Cycloaddition of Chiral Nonracemic Fischer Carbene Complexes with Azomethine Ylides: An Enantioselective Synthesis of (+)-Rolipram
  作者：José Barluenga、Manuel A. Fernández-Rodríguez、Enrique Aguilar、Félix Fernández-Marí、Alejandro Salinas、Bernardo Olano

  DOI：10.1002/1521-3765(20010817)7:16<3533::aid-chem3533>3.0.co;2-e

  日期：2001.8.17

  A new procedure for the synthesis of 1,3,4-trisubstituted and 1,4-disubstituted pyrrolidin-2-one derivatives in an enantioselective fashion is reported. The 1,3-dipolar cycloaddition of (+/-)-menthol and (-)-8-phenylmenthol derived Fischer alkoxy alkenyl carbene complexes with in situ generated functionalized azomethine ylides gives the corresponding cycloadducts as chelated tetracarbonyl Fischer carbene

  报道了以对映选择性的方式合成1,3,4-三取代和1,4-二取代的吡咯烷-2-酮衍生物的新方法。（+/-）-薄荷醇和（-）-8-苯基薄荷醇的1，3-偶极环加成与原位产生的官能化的偶氮甲亚胺的费希尔烷氧基烯基卡宾卡宾配合物产生相应的环加合物，为螯合的四羰基菲舍尔卡宾配合物。在所有情况下仅检测到一种区域异构体，并且当使用（-）-8-苯基薄荷醇衍生的卡宾时，反应的非对映选择性非常高。环加合物的氧化和进一步转化提供了容易获得吡咯烷基-2-酮的途径。利用这种新开发的方法，可以很容易地通过四个步骤以20％的总产率制备抗炎和抗抑郁药（+）-咯利普兰。
• PYRAZOLE DERIVATIVES
  申请人：SYNGENTA CROP PROTECTION AG

  公开号：US20200245625A1

  公开（公告）日：2020-08-06

  The present invention relates to pyrazole derivatives of formula (X) wherein ring A is a pyrazole and substituents R B1 , R B2 , n, R Q1 , R Q2 , R Q3 , and R Q4 are as defined in claim 1 , their manufacture, and their use in the manufacture of agrochemicals and pharmaceuticals.

  本发明涉及式（X）的吡唑衍生物，其中环A为吡唑，取代基RB1、RB2、n、RQ1、RQ2、RQ3和RQ4如权利要求1所定义，它们的制造以及它们在农药和药品制造中的应用。
• Dithiolane-isocyanate imminium methylides: A rapid stereoselective entry into γ-lactams
  作者：Colin W.G. Fishwick、Richard J. Foster、Robin E. Carr

  DOI：10.1016/0040-4039(95)01998-w

  日期：1995.12

  Methods have been developed for the generation and trapping of dithiolane-isocyanate imminium methylides which are a new type of azomethine methylide-derived 1,3-dipole. These species add efficiently and stereoselectively to electron deficient olefins yielding novel dithiolane-protected gamma-lactans which can be efficiently deprotected to yield to corresponding lactam systems.