N,N'-di(methoxycarbonyl)propane-1,1-diamine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N,N'-di(methoxycarbonyl)propane-1,1-diamine
• 英文别名: methyl N-[1-(methoxycarbonylamino)propyl]carbamate
• 化学式: C₇H₁₄N₂O₄
• 分子量: 190.199
• InChiKey: VHPBGUJMAPSUBT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  76.7
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (Z)-1-(trimethylsilyl)dodec-1-ene 、 N,N'-di(methoxycarbonyl)propane-1,1-diamine 在 silver hexafluoroantimonate 、 platinum(II) chloride 、 三氟化硼乙醚 作用下， 以 1,2-二氯乙烷 、 乙腈 为溶剂， 反应 50.0h， 以231 mg的产率得到N-methoxycarbonyl-4-nonylhex-5-en-3-amine
  参考文献：
  名称：

  Regioselective Allylation of Carbon Electrophiles with Alkenyl­silanes under Dual Catalysis by Cationic Platinum(II) Species

  摘要：

  In the presence of catalytic amounts of platinum(II) chloride and silver(I) hexafluoroantimonate, (Z)-alkenylsilanes reacted with various carbon electrophiles (acetals, aminals, carboxylic anhydrides, alkyl chlorides, etc.) at the -position to give allylation products. A plausible mechanism for the platinum-catalyzed allylation involves alkene migration of alkenylsilanes to allylsilanes and subsequent allylation of carbon electrophiles, both of which are catalyzed by a cationic platinum(II) species.

  DOI：

  10.1055/s-0035-1560380
• 作为产物：
  描述：

  丙醛 、 氨基甲酸甲酯 在 三氟化硼乙醚 作用下， 以 乙醚 为溶剂， 反应 1.0h， 生成 N,N'-di(methoxycarbonyl)propane-1,1-diamine
  参考文献：
  名称：

  Regioselective Allylation of Carbon Electrophiles with Alkenyl­silanes under Dual Catalysis by Cationic Platinum(II) Species

  摘要：

  In the presence of catalytic amounts of platinum(II) chloride and silver(I) hexafluoroantimonate, (Z)-alkenylsilanes reacted with various carbon electrophiles (acetals, aminals, carboxylic anhydrides, alkyl chlorides, etc.) at the -position to give allylation products. A plausible mechanism for the platinum-catalyzed allylation involves alkene migration of alkenylsilanes to allylsilanes and subsequent allylation of carbon electrophiles, both of which are catalyzed by a cationic platinum(II) species.

  DOI：

  10.1055/s-0035-1560380

文献信息

• Regioselective Allylation of Carbon Electrophiles with Alkenyl­silanes under Dual Catalysis by Cationic Platinum(II) Species
  作者：Katsukiyo Miura、Hidenori Kinoshita、Ryosuke Kizu、Masahiro Horikoshi、Gen Inoue、Masayuki Fujimoto、Masanori Saito、Junji Ichikawa、Akira Hosomi

  DOI：10.1055/s-0035-1560380

  日期：——

  In the presence of catalytic amounts of platinum(II) chloride and silver(I) hexafluoroantimonate, (Z)-alkenylsilanes reacted with various carbon electrophiles (acetals, aminals, carboxylic anhydrides, alkyl chlorides, etc.) at the -position to give allylation products. A plausible mechanism for the platinum-catalyzed allylation involves alkene migration of alkenylsilanes to allylsilanes and subsequent allylation of carbon electrophiles, both of which are catalyzed by a cationic platinum(II) species.