2-(2-(2-hydroxyethoxy)ethoxy)ethyl 2-(2,4-dichlorophenoxy)acetate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(2-(2-hydroxyethoxy)ethoxy)ethyl 2-(2,4-dichlorophenoxy)acetate
• 英文别名: 8-hydroxy-3,6-dioxaoctyl 2,4-dichlorophenoxyacetate；2-[2-(2-hydroxyethoxy)ethoxy]ethyl 2-(2,4-dichlorophenoxy)acetate
• 化学式: C₁₄H₁₈Cl₂O₆
• 分子量: 353.199
• InChiKey: OXTORITXPRYKPO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  22
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  74.2
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  5-[2-氯-4-(三氟甲基)苯氧基]-2-硝基苯甲酰氯 、 2-(2-(2-hydroxyethoxy)ethoxy)ethyl 2-(2,4-dichlorophenoxy)acetate 、 三乙胺 、 四氢呋喃 在 碳酸氢钠 、 水 、 乙醚 、 magnesium sulfate 、 8-(2,4-Dichlorophenoxyacetoxy)-3,6-dioxaoctyl 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitrobenzoate 作用下， 以 乙醚 为溶剂， 反应 3.08h， 生成 8-(2,4-Dichlorophenoxyacetoxy)-3,6-dioxaoctyl 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitrobenzoate
  参考文献：
  名称：

  Substituted diphenyl ether herbicides and process for use

  摘要：

  本发明涉及具有选择性除草性能的取代二苯醚，其化学式为：##STR1## 其中R是由1至18个碳原子组成的饱和或不饱和的直链或支链脂肪烃基，其中一个或多个--CH.sub.2--基团可以被--O--，--S--，--S--S--，--SO--，--SO.sub.2--或--NR.sub.2--所取代，所述碳氢基团可以选择性地被取代，所取代的基团为卤素，三卤甲基，氰基，芳基，羟基，烷氧基，硝基或含3至6个碳原子的环烷基；R.sub.1是##STR2## R.sub.3是##STR3## R.sub.2是氢或由1至8个碳原子组成的饱和或不饱和的直链或支链脂肪基，可以选择性地被卤素，羟基，烷氧基，氰基或硝基所取代；R.sub.4和R.sub.5分别是由1至8个碳原子组成的饱和或不饱和的直链或支链脂肪基，可以选择性地被卤素，三卤甲基，烷氧基或氰基所取代；氢或苯基，可以选择性地被卤素，烷基，烷氧基，三卤甲基，硝基或氰基所取代；R.sub.6是由1至8个碳原子组成的饱和或不饱和的直链或支链脂肪基，可以选择性地被卤素，三卤甲基，氰基，羟基，硝基，乙酰氧基，烷氧基，硫代烷氧基或芳基所取代；芳基可以选择性地被卤素，三卤甲基，羟基，氰基，硝基，烷基或烷氧基所取代；环状3-6成员环烷基或5-6成员环烯基或苯甲基，可以选择性地被卤素，三卤甲基，烷基，羟基，烷氧基或氰基所取代；R.sub.7是由1至6个碳原子组成的烷基二重基；X和X'各自独立地是--O--，--S--或--NR.sub.2--；L，M和N各自独立地是氢，羟基，卤素，三卤甲基，硝基，氰基，烷基或烷氧基，其碳原子数为1至4，并且##STR4## m的值为1至6，每种情况下n的值为0至1。

  公开号：

  US04429146A1
• 作为产物：
  描述：

  2,4-二氯苯氧乙酸 、 三乙二醇 在 碘 作用下， 以 甲苯 为溶剂， 以72%的产率得到2-(2-(2-hydroxyethoxy)ethoxy)ethyl 2-(2,4-dichlorophenoxy)acetate
  参考文献：
  名称：

  Design, synthesis and herbicidal activities of novel self-dispreading phenoxy carboxylic acid derivatives for the control of water hyacinth floating on the water surface

  摘要：

  A series of novel self-dispreading phenoxy carboxylic acid derivatives were designed and synthesized by I-2 catalyzed one-step reaction. Their structures were confirmed by IR, NMR, and HRMS. The derivatives can self-spread and float on the water surface. Preliminary bioassays showed that some compounds, 3i-3p, had excellent herbicidal activities against water hyacinth. This strategy provided a novel approach for the water hyacinth control. (C) 2015 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.cclet.2015.04.008

文献信息

• New phenoxybenzoates, process for preparing these compounds, compositions containing them and method of use
  申请人：GAF CORPORATION

  公开号：EP0066106A1

  公开（公告）日：1982-12-08

  This invention relates to new phenoxybenzoates having high pre- and post- emergence herbicidal activity against indicator weeds; and are particularly effective against broadleaf weeds, such as morning glory. In addition to such effective herbicidal activity, they exhibit an unusual selectivity against important agromonic crops, such as cotton, rice, soybean, corn, wheat and sorghum.

  本发明涉及新型苯氧基苯甲酸酯，对指示性杂草具有很高的出苗前和出苗后除草活性；对阔叶杂草（如牵牛花）特别有效。除了这种有效的除草活性外，它们还对重要的农作物，如棉花、水稻、大豆、玉米、小麦和高粱表现出不同寻常的选择性。
• MACROMOLECULAR AND NONPARTICULATE AGROCHEMICALS TO REDUCE VAPOR DRIFT
  申请人：University of Utah Research Foundation

  公开号：US20210352892A1

  公开（公告）日：2021-11-18

  The invention generally relates to agrochemical compositions and methods of making and using same. Specifically, the disclosed agrochemical compositions comprise high molecular weight non-polymeric residues or polymer backbones, and pesticide residues covalently attached thereto. Such compositions can be useful in, for example, controlling plant growth. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
• US4429146A
  申请人：——

  公开号：US4429146A

  公开（公告）日：1984-01-31
• Design, synthesis and herbicidal activities of novel self-dispreading phenoxy carboxylic acid derivatives for the control of water hyacinth floating on the water surface
  作者：Lv-Yin Zheng、Ren-Miao Wu、Wei Guo、Wen-Hua You、Yan-Lan Ling、Xiao-Lin Fan

  DOI：10.1016/j.cclet.2015.04.008

  日期：2015.8

  A series of novel self-dispreading phenoxy carboxylic acid derivatives were designed and synthesized by I-2 catalyzed one-step reaction. Their structures were confirmed by IR, NMR, and HRMS. The derivatives can self-spread and float on the water surface. Preliminary bioassays showed that some compounds, 3i-3p, had excellent herbicidal activities against water hyacinth. This strategy provided a novel approach for the water hyacinth control. (C) 2015 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
• Substituted diphenyl ether herbicides and process for use
  申请人：GAF Corporation

  公开号：US04429146A1

  公开（公告）日：1984-01-31

  This invention relates to substituted diphenyl ethers having selective herbicidal properties and having the formula: ##STR1## wherein R is a saturated or unsaturated, straight chain or branched aliphatic hydrocarbon radical of from 1 to 18 carbon atoms wherein one or more of the --CH.sub.2 -- groups can be replaced with --O--, --S--, --S--S--, --SO--, --SO.sub.2 -- or --NR.sub.2 -- and said hydrocarbon radical is optionally substituted with halogen, trihalomethyl, cyano, aryl, hydroxy, alkoxy, nitro or cycloalkyl having 3 to 6 carbon atoms; R.sub.1 is ##STR2## R.sub.3 is ##STR3## R.sub.2 is hydrogen or a saturated or unsaturated straight or branched chain aliphatic radical having from 1 to 8 carbon atoms, optionally substituted with halogen, hydroxy, alkoxy, cyano or nitro; R.sub.4 and R.sub.5 are independently a saturated or unsaturated, straight or branched chain aliphatic radical having 1 to 8 carbon atoms optionally substituted with halogen, trihalomethyl, alkoxy or cyano; hydrogen or phenyl optionally substituted with halogen, alkyl, alkoxy, trihalomethyl, nitro or cyano; R.sub.6 is a saturated or unsaturated straight chain or branched aliphatic radical containing from 1 to 8 carbon atoms, optionally substituted with halogen, trihalomethyl, cyano, hydroxy, nitro, acetoxy, alkoxy, thioalkoxy or aryl; an aryl radical optionally substituted with halogen, trihalomethyl, hydroxy, cyano, nitro, alkyl or alkoxy; a cyclic 3-6 membered ring alkylene or 5-6 membered ring alkenylene or benzyl optionally substituted with halogen, trihalomethyl, alkyl, hydroxy, alkoxy or cyano; R.sub.7 is an alkylene diradical having from 1 to 6 carbon atoms; X and X' are each independently --O--, --S-- or --NR.sub.2 -- L, M and N are each independently hydrogen, hydroxy, halogen, trihalomethyl, nitro, cyano, alkyl or alkoxy having from 1 to 4 carbon atoms and ##STR4## m has a value of from 1 to 6 and n in each instance has a value of from 0 to 1.

  这项发明涉及具有选择性除草特性的取代二苯醚，其化学式为：其中R是具有1至18个碳原子的饱和或不饱和、直链或支链脂肪烃基，其中一个或多个--CH.sub.2--基团可以被--O--、--S--、--S--S--、--SO--、--SO.sub.2--或--NR.sub.2--取代，且该烃基可以选择性地被卤素、三卤甲基、氰基、芳基、羟基、烷氧基、硝基或具有3至6个碳原子的环烷基取代；R.sub.1是；R.sub.3是；R.sub.2是氢或具有1至8个碳原子的饱和或不饱和、直链或支链脂肪基，可以选择性地被卤素、羟基、烷氧基、氰基或硝基取代；R.sub.4和R.sub.5分别是具有1至8个碳原子的饱和或不饱和、直链或支链脂肪基，可以选择性地被卤素、三卤甲基、烷氧基或氰基取代；氢或苯基，可以选择性地被卤素、烷基、烷氧基、三卤甲基、硝基或氰基取代；R.sub.6是具有1至8个碳原子的饱和或不饱和直链或支链脂肪基，可以选择性地被卤素、三卤甲基、氰基、羟基、硝基、乙酰氧基、烷氧基、硫代烷氧基或芳基取代；一种芳基，可以选择性地被卤素、三卤甲基、羟基、氰基、硝基、烷基或烷氧基取代；一个环状3-6成员环烷基或5-6成员环烯基或苄基，可以选择性地被卤素、三卤甲基、烷基、羟基、烷氧基或氰基取代；R.sub.7是具有1至6个碳原子的烷基二基；X和X'各自独立地是--O--、--S--或--NR.sub.2--；L、M和N各自独立地是氢、羟基、卤素、三卤甲基、硝基、氰基、具有1至4个碳原子的烷基或烷氧基；m的值为1至6，每种情况下n的值为0至1。