2-[2-{2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}phenoxy]propionic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[2-{2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}phenoxy]propionic acid
• 英文别名: 2-[2-[2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]phenoxy]phenoxy]propanoic acid
• 化学式: C₂₁H₁₅ClF₄N₂O₆
• 分子量: 502.807
• InChiKey: LBNNJPUKWWIVNN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  34
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  96.4
• 氢给体数：
  1
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  2-[2-{2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}phenoxy]propionic acid 在 四氢呋喃 、 戊醇 、 solution A 、 吡啶 、 盐酸 、 乙酸乙酯 、 氯化钠 、 magnesium sulfate 作用下， 以 四氢呋喃 、 氯化亚砜 为溶剂， 以to give pentyl 2-[2-{2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}phenoxy]propionate (compound b-19)的产率得到pentyl 2-[2-{2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}phenoxy]propionate
  参考文献：
  名称：

  Plant growth regulators for cotton hervest

  摘要：

  一种用于棉花收获的植物生长调节剂，其包含以下化合物作为活性成分：式（I）中，X为CH或氮；Z为卤素；A为氧、硫或NH；R1为羟基、C1-C7烷氧基、C3-C7烯氧基、C3-C7炔氧基、C5-C7环烷氧基、(C1-C7烷氧基)羰基C1-C3烷氧基、(C1-C7烷基氨基)氧基、二(C1-C7烷基)-氨基氧基、(C3-C7烷基亚甲基氨基)氧基、C1-C7烷基氨基、二(C1-C7烷基)-氨基、C3-C7烯基氨基、C3-C7炔基氨基、C5-C7环烷基氨基、(C1-C7烷氧基)羰基C1-C3烷基氨基或(C1-C7烷氧基)氨基；R2为氢或甲基；R3为氢、卤素、C1-C3烷基或C1-C3烷氧基。

  公开号：

  US20040152597A1
• 作为产物：
  描述：

  methyl 2-[2-{2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}phenoxy] propionate 在 盐酸 、 水 作用下， 以 1,4-二氧六环 为溶剂， 反应 5.75h， 生成 2-[2-{2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}phenoxy]propionic acid
  参考文献：
  名称：

  STEM/LEAF DESICCANT

  摘要：

  公开号：

  EP1397958B1

文献信息

• Uracil compounds and use thereof
  申请人：——

  公开号：US20020013466A1

  公开（公告）日：2002-01-31

  The present invention relates to an uracil compound of the formula [I]: 1 wherein W represents oxygen, sulfur, imino or C 1 to C 3 alkylimino; Y represents oxygen, sulfur, imino or C 1 to C 3 alkylimino; R 1 represents C 1 to C 3 alkyl or C 1 to C 3 haloalkyl; R 2 represents C 1 to C 3 alkyl; R 4 represents hydrogen or methyl; R 5 represents C 1 to C 6 alkyl, C 1 to C 6 haloalkyl, or the like; X 1 represents halogen, cyano or nitro; X 2 represents hydrogen or halogen; and each of X 3 and X 4 independently represents hydrogen, halogen, C 1 to C 6 alkyl, or the like. The present compound has an excellent herbicidal activity.

  本发明涉及一种式子为[I]的尿嘧啶化合物，其中W代表氧、硫、亚硝基或C1到C3烷基亚硝基；Y代表氧、硫、亚硝基或C1到C3烷基亚硝基；R1代表C1到C3烷基或C1到C3卤代烷基；R2代表C1到C3烷基；R4代表氢或甲基；R5代表C1到C6烷基、C1到C6卤代烷基或类似物；X1代表卤素、氰基或硝基；X2代表氢或卤素；以及X3和X4分别独立地代表氢、卤素、C1到C6烷基或类似物。该化合物具有出色的除草活性。
• Plant growth regulators for cotton hervest
  申请人：——

  公开号：US20040152597A1

  公开（公告）日：2004-08-05

  A plant growth regulator for cotton harvest, which contains as an active ingredient, a compound of formula (I): 1 wherein X is CH or nitrogen; Z is halogen; A is oxygen, sulfur, or NH; R 1 is hydroxyl, C 1 -C 7 alkoxy, C 3 -C 7 alkenyloxy, C 3 -C 7 alkynyloxy, C 5 -C 7 cycloalkoxy, {(C 1 -C 7 alkoxy)carbonyl}C 1 -C 3 alkoxy, (C 1 -C 7 alkylamino)oxy, {di(C 1 -C 7 alkyl)-amino}oxy, (C 3 -C 7 alkylideneamino)oxy, C 1 -C 7 alkylamino, di(C 1 -C 7 alkyl)-amino, C 3 -C 7 alkenylamino, C 3 -C 7 alkynylamino, C 5 -C 7 cycloalkylamino, {(C 1 -C 7 alkoxy)carbonyl}C 1 -C 3 alkylamino, or (C 1 -C 7 alkoxy)amino; R 2 is hydrogen or methyl; and R 3 is hydrogen, halogen, C 1 -C 3 alkyl, or C 1 -C 3 alkoxy.

  一种用于棉花收获的植物生长调节剂，其包含以下化合物作为活性成分：式（I）中，X为CH或氮；Z为卤素；A为氧、硫或NH；R1为羟基、C1-C7烷氧基、C3-C7烯氧基、C3-C7炔氧基、C5-C7环烷氧基、(C1-C7烷氧基)羰基C1-C3烷氧基、(C1-C7烷基氨基)氧基、二(C1-C7烷基)-氨基氧基、(C3-C7烷基亚甲基氨基)氧基、C1-C7烷基氨基、二(C1-C7烷基)-氨基、C3-C7烯基氨基、C3-C7炔基氨基、C5-C7环烷基氨基、(C1-C7烷氧基)羰基C1-C3烷基氨基或(C1-C7烷氧基)氨基；R2为氢或甲基；R3为氢、卤素、C1-C3烷基或C1-C3烷氧基。
• Uracil compounds and their use
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP1106607A2

  公开（公告）日：2001-06-13

  The present invention relates to an uracil compound of the formula [I]: wherein W represents oxygen, sulfur, imino or C1 to C3 alkylimino; Y represents oxygen, sulfur, imino or C1 to C3 alkylimino; R1 represents C1 to C3 alkyl or C1 to C3 haloalkyl; R2 represents C1 to C3 alkyl; R4 represents hydrogen or methyl; R5 represents C1 to C6 alkyl, C1 to C6 haloalkyl, or the like; X1 represents halogen, cyano or nitro; X2 represents hydrogen or halogen; and each of X3 and X4 independently represents hydrogen, halogen, C1 to C6 alkyl, or the like. The present compound has an excellent herbicidal activity.

  本发明涉及一种式[I]的尿嘧啶化合物： 其中W代表氧、硫、亚氨基或C1至C3烷基亚氨基；Y代表氧、硫、亚氨基或C1至C3烷基亚氨基；R1代表C1至C3烷基或C1至C3卤代烷基；R2代表C1至C3烷基；R4代表氢或甲基；R5代表C1至C6烷基、C1至C6卤代烷基或类似物；X1代表卤素、氰基或硝基；X2代表氢或卤素；X3和X4各自独立地代表氢、卤素、C1至C6烷基或类似物。本化合物具有优异的除草活性。
• STEAM/LEAF DESSICANT
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP1397958A1

  公开（公告）日：2004-03-17

  A stem/leaf desiccant for crop plants which comprises as an active ingredient, a compound of formula (I): wherein X represent CH or nitrogen; Z represents halogen; A represents oxygen, sulfur, or NH; R1 represents hydroxyl, C1-C7 alkoxy, C3-C7 alkenyloxy, C3-C7 alkynyloxy, C5-C7 cycloalkoxy, (C1-C7 alkoxy)carbonyl} C1-C3 alkoxy, (C1-C7 alkylamino)oxy, di(C1-C7 alkyl)amino}oxy, (C3-C7 alkylideneamino)oxy, C1-C7 alkylamino, di(C1-C7 alkyl)amino, C3-C7 alkenylamino, C3-C7 alkynylamino, C5-C7 cycloalkylamino, (C1-C7 alkoxy)carbonyl} C1-C3 alkylamino, or (C1-C7 alkoxy)amino; R2 is hydrogen or methyl; and R3 is hydrogen, halogen, C1-C3 alkyl, or C1-C3 alkoxy;    a method for desiccating a crop plant and a method for harvesting a crop by using the stem/leaf desiccant.

  一种农作物茎叶干燥剂，其活性成分包括式（I）化合物： 其中 X 代表 CH 或氮；Z 代表卤素；A 代表氧、硫或 NH；R1 代表羟基、C1-C7 烷氧基、C3-C7 烯氧基、C3-C7 烷炔氧基、C5-C7 环烷氧基、(C1-C7 烷氧基)羰基｝C1-C3烷氧基，(C1-C7烷基氨基)氧基，二(C1-C7烷基)氨基}氧基，(C3-C7亚烷基氨基)氧基，C1-C7烷基氨基，二(C1-C7烷基)氨基，C3-C7烯基氨基，C3-C7炔基氨基，C5-C7环烷基氨基，(C1-C7烷氧基)羰基}。C1-C3 烷基氨基或 (C1-C7 烷氧基)氨基；R2 是氢或甲基；R3 是氢、卤素、C1-C3 烷基或 C1-C3 烷氧基； 一种干燥作物植株的方法，以及一种通过使用茎/叶干燥剂收获作物的方法。
• HERBICIDE COMPOSITION
  申请人：SUMITOMO CHEMICAL COMPANY LIMITED

  公开号：EP1430775A1

  公开（公告）日：2004-06-23

  The present invention relates to an herbicide composition comprising, as active ingredients, a uracil compound represented by the following formula (I):    wherein Z represents halogen or cyano; A represents oxygen, sulfur or NH; R1 represents hydroxyl, C1-C7 alkoxy or others, and R2 represents hydrogen or methyl, and one or more organophosphorus compounds selected from the group consisting of N-(phosphonomethyl)glycine, agriculturally acceptable salts of Glyphosate and ammonium DL-homoalanine-4-yl(methyl)phosphinate; and a method for controlling weeds which comprises applying an effective amount of said herbicide composition to weeds. According to the invention, particularly weeds in orchards, cornfields, soybean fields, cotton fields and non-crop lands can be effectively controlled.

  本发明涉及一种除草剂组合物，其活性成分包括下式(I)代表的尿嘧啶化合物： 其中 Z 代表卤素或氰基；A 代表氧、硫或 NH；R1 代表羟基、C1-C7 烷氧基或其它，R2 代表氢或甲基、 和一种或多种选自 N-(膦酰甲基)甘氨酸、草甘膦的农业上可接受的盐和 DL-高丙氨酸-4-基(甲基)膦酸铵所组成的组的有机磷化合物；以及一种控制杂草的方法，该方法包括向杂草施用有效量的所述除草组合物。 根据本发明，尤其可以有效控制果园、玉米田、大豆田、棉花田和非作物地的杂草。