4-[2-(4-methylphenyl)ethenyl]pyridine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-[2-(4-methylphenyl)ethenyl]pyridine
• 英文别名: 4-(4-Methylstyryl) pyridine
• 化学式: C₁₄H₁₃N
• 分子量: 195.264
• InChiKey: GQLIWGHJUSUIRN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4-[2-(4-methylphenyl)ethenyl]pyridine 在 溴 、 potassium hydroxide 作用下， 以 乙醇 、 溶剂黄146 为溶剂， 生成 4-<4-Methyl-phenylethinyl>-pyridin
  参考文献：
  名称：

  Photo-dehydro-Diels–Alder reaction of 1-phenyl-2-(pyridyl)acetylenes in acidic aqueous solution

  摘要：

  The photocycloaddition of 1-(4-R-phenyl)-2-(4-pyridyl)acetylenes (R = H, Br, CH3, Cl) and 1-(4-R-phenyl)-2-(2-pyridyl)acetylenes (R = H, Br, Cl) was carried out in acidic aqueous solution. The unexpected photo-dehydro-Diels-Alder reaction of these monomers was observed, and the results show that two monomers react in a head-to-tail manner and lead to the formation of 2-phenyl-1,3-di(pyridyl)naphthalene derivatives. This reaction presents a direct metal-free method to construct the 1,2,3-triaryl substituted naphthalenes from diarylacetylenes. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jphotochem.2013.07.004
• 作为产物：
  描述：

  4-甲基吡啶 、 对甲基苯甲醛 在 lithium diisopropyl amide 、 溶剂黄146 作用下， 以 四氢呋喃 为溶剂， 反应 18.0h， 以80%的产率得到4-[2-(4-methylphenyl)ethenyl]pyridine
  参考文献：
  名称：

  甲基三氧铼的发色路易斯碱加合物：合成、催化和光化学

  摘要：

  研究了一系列甲基三氧铼 (MTO) 的发色路易斯碱加合物。配体是具有不同大小的芳香系统和可变取代基的吡啶衍生物，因此提供了电子和空间参数的变化。对配合物进行了充分表征（UV/Vis、IR 和 NMR 光谱、单晶 X 射线衍射和元素分析），并通过 UV/Vis 光谱测定了它们在二氯甲烷中的稳定性常数。此外，本报告还研究了与 MTO 配位的这些 N-供体配体对 1-辛烯环氧化催化活性的影响。每个化合物测试两次；在避光和日光下进行催化反应。未发现催化性能有显着差异。通过 (17)O-NMR 和 UV/Vis 光谱研究了配合物在紫外光照射下的行为。本文公开的实验旨在探讨 MTO 加合物中发色 N 供体配体的潜在有益作用，因为它们可能通过提供额外的能量来削弱在催化循环中必须断裂的键来激活催化系统。

  DOI：

  10.1002/ejic.201000348

文献信息

• Facile and highly selective silylation of vinylpyridines at the β-olefinic carbon by magnesium-promoted reduction
  作者：Tianyuan Zhang、Zeyu Zhang、Yutaro Nishiyama、Hirofumi Maekawa

  DOI：10.1016/j.tet.2016.03.042

  日期：2016.5

  Magnesium-promoted reductive silylation of 2- and 4-vinylpyridines with chlorotrialkylsilanes in N-methylpyrrolidinone at room temperature led to the selective formation of a variety of the corresponding β-mono-silylated compounds at the terminal carbon atom in good to excellent yields, whereas silylation of 3-vinylpyridine under the same reduction conditions failed to give a complex mixture of silylated

  在室温下，镁在N-甲基吡咯烷酮中用氯三烷基硅烷促进2-和4-乙烯基吡啶的还原甲硅烷基化，从而导致在末端碳原子上选择性形成各种相应的β-单甲硅烷基化化合物，而收率很好，反而更好。在相同的还原条件下使3-乙烯基吡啶甲硅烷基化不能得到甲硅烷基化化合物的复杂混合物。2-或4-乙烯基吡啶与3-乙烯基吡啶之间的结果差异归因于通过与吡啶的氮原子的共振对反应中间体的稳定作用。
• Chromophoric Lewis Base Adducts of Methyltrioxorhenium: Synthesis, Catalysis and Photochemistry
  作者：Simone A. Hauser、Valentina Korinth、Eberhardt Herdtweck、Mirza Cokoja、Wolfgang A. Herrmann、Fritz E. Kühn

  DOI：10.1002/ejic.201000348

  日期：2010.9

  A series of chromophoric Lewis base adducts of methyltrioxorhenium (MTO) was examined. The ligands were pyridine derivatives with different size of the aromatic system and variable substituents, thus providing a variation of electronic and steric parameters. The complexes were fully characterised (UV/Vis, IR and NMR spectroscopy, single-crystal X-ray diffraction and elemental analysis) and their stability

  研究了一系列甲基三氧铼 (MTO) 的发色路易斯碱加合物。配体是具有不同大小的芳香系统和可变取代基的吡啶衍生物，因此提供了电子和空间参数的变化。对配合物进行了充分表征（UV/Vis、IR 和 NMR 光谱、单晶 X 射线衍射和元素分析），并通过 UV/Vis 光谱测定了它们在二氯甲烷中的稳定性常数。此外，本报告还研究了与 MTO 配位的这些 N-供体配体对 1-辛烯环氧化催化活性的影响。每个化合物测试两次；在避光和日光下进行催化反应。未发现催化性能有显着差异。通过 (17)O-NMR 和 UV/Vis 光谱研究了配合物在紫外光照射下的行为。本文公开的实验旨在探讨 MTO 加合物中发色 N 供体配体的潜在有益作用，因为它们可能通过提供额外的能量来削弱在催化循环中必须断裂的键来激活催化系统。
• Photosensitive resin composition
  申请人：The Chromaline Corporation

  公开号：US05506089A1

  公开（公告）日：1996-04-09

  A universal method to make photosensitive polymers from poly(vinyl alcohol) and poly(vinyl pyridine) is disclosed which generally does not require final purification and can produce photosensitive polymers which are of similar photosensity whether prepared with a poly(vinyl alcohol) or poly(vinyl pyridine) backbone. These polymers comprise a heterocyclic, light-sensitive pendant group including a moiety having the formula: ##STR1## wherein Z.sup.1 denotes the atoms necessary to form a substituted or unsubstituted aromatic heterocyclic ring; Z.sup.2 denotes the atoms necessary to form a substituted or unsubstituted aromatic or aromatic heterocyclic ring; R is hydrogen or a substituted or unsubstituted alkyl group; M is a divalent organic moiety; Y is a residue from a grafting group that is capable of grafting the pendant group onto a polymeric backbone.

  公开了一种从聚乙烯醇和聚乙烯吡啶制备光敏聚合物的通用方法，通常不需要最终纯化，并且可以产生具有相似光敏度的光敏聚合物，无论是使用聚乙烯醇还是聚乙烯吡啶骨架制备。这些聚合物包括一个杂环、光敏感的挂链基团，包括具有以下式子的基团：##STR1## 其中Z.sup.1表示形成取代或未取代芳香杂环环所需的原子；Z.sup.2表示形成取代或未取代芳香或芳香杂环环所需的原子；R是氢或取代或未取代的烷基；M是二价有机基团；Y是能够将挂链基团嫁接到聚合物骨架上的嫁接基团的残基。
• Selective introduction of a trifluoroacetyl group onto 4-vinylpyridines through magnesium-promoted reduction
  作者：Hirofumi Maekawa、Yutaro Nishiyama

  DOI：10.1016/j.tet.2015.07.046

  日期：2015.9

  Magnesium-promoted reductive coupling of 4-vinylpyridines and ethyl trifluoroacetate in the presence of chlorotrimethylsilane in N-methyl-2-pyrrolidone resulted in selective formation of the tri-fluoroacetylated compounds at the beta-olefinic carbon of the pyridine ring, the electron deficient carbon in good yields. In particular, 4-vinylpyridine with an aromatic ring at the beta-olefinic position of the pyridine ring gave higher yield of the trifluoroacetylated compound. The nitrogen atom of the pyridine ring may play an important role in the regioselectivity of the product. (C) 2015 Elsevier Ltd. All rights reserved.
• Photo-dehydro-Diels–Alder reaction of 1-phenyl-2-(pyridyl)acetylenes in acidic aqueous solution
  作者：Junpeng Zhuang、Shuguang Zhang、Haijun Hao、Long Jiang

  DOI：10.1016/j.jphotochem.2013.07.004

  日期：2013.10

  The photocycloaddition of 1-(4-R-phenyl)-2-(4-pyridyl)acetylenes (R = H, Br, CH3, Cl) and 1-(4-R-phenyl)-2-(2-pyridyl)acetylenes (R = H, Br, Cl) was carried out in acidic aqueous solution. The unexpected photo-dehydro-Diels-Alder reaction of these monomers was observed, and the results show that two monomers react in a head-to-tail manner and lead to the formation of 2-phenyl-1,3-di(pyridyl)naphthalene derivatives. This reaction presents a direct metal-free method to construct the 1,2,3-triaryl substituted naphthalenes from diarylacetylenes. (C) 2013 Elsevier B.V. All rights reserved.