2,6-diisobornylphenol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,6-diisobornylphenol
• 英文别名: 2,6-bis(1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl)phenol
• 化学式: C₂₆H₃₈O
• 分子量: 366.587
• InChiKey: MIZVZCOZDYEJKF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.2
• 重原子数：
  27
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2,6-diisobornylphenol 在 sodium tetrahydroborate 、 氯化亚砜 、 N,N-二甲基甲酰胺 、 硫酸二甲酯 、 potassium hydroxide 作用下， 以 四氢呋喃 、 丙酮 为溶剂， 反应 8.0h， 生成
  参考文献：
  名称：

  Synthesis and Properties of Functional Derivatives of 2,6-Diisobornylphenol and 2-Isobornyl-6-(1-phenylethyl)phenol

  摘要：

  New isobornylphenol derivatives have been produced by introducing allyl, hydroxypropyl, and chloropropyl groups into the para-position of 2,6-diisobornylphenol and 2-isobornyl-6-(1-phenylethyl)phenol. The radical scavenging and antioxidant activity and the membrane-protective properties of the newly-obtained compounds in chemical and biological model systems were studied.

  DOI：

  10.1134/s1070363218040096
• 作为产物：
  描述：

  莰烯 、 2-叔丁基苯酚 在 aluminum isopropoxide 作用下， 反应 46.0h， 以57%的产率得到2,6-diisobornylphenol
  参考文献：
  名称：

  Synthesis of phenolic antioxidants with isobornyl and tert-butyl fragments

  摘要：

  Hybrid antioxidants, phenols with a terpene and tert-butyl substituents, were synthesized by the alkylation of 2-tert-butyl-4-methylphenol with camphene and 2-isobornylphenol with tert-butyl chloride in the presence of acidic heterogeneous catalysts, montmorillonite KSF and FIBAN K-1. Antioxidant activity of the synthesized terpenophenols was evaluated using spectrophotometry.

  DOI：

  10.1134/s1070363213060170

文献信息

• Synthesis and molecular structure of di(4-hydroxy-2,6-diisoborn-2-ylphenyl)methane
  作者：E. V. Buravlev、I. Yu. Chukicheva、K. Yu. Suponitsky、A. V. Kutchin

  DOI：10.1134/s1070363213070086

  日期：2013.7

  Di(4-hydroxy-2-(1R*,2S*,4S*)-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl}-6-(1S*,2R*,4R*)-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl})methane was synthesized by condensation of the meso-diastereomer of 2,6-diisobornylphenol with paraformaldehyde under acid catalysis. The product structure as a meso-forms was confirmed by XRD analysis.
• US3931298A
  申请人：——

  公开号：US3931298A

  公开（公告）日：1976-01-06
• US3960962A
  申请人：——

  公开号：US3960962A

  公开（公告）日：1976-06-01
• US3965182A
  申请人：——

  公开号：US3965182A

  公开（公告）日：1976-06-22
• Synthesis of phenolic antioxidants with isobornyl and tert-butyl fragments
  作者：I. V. Fedorova、I. Yu. Chukicheva、O. A. Shumova、A. V. Kutchin

  DOI：10.1134/s1070363213060170

  日期：2013.6

  Hybrid antioxidants, phenols with a terpene and tert-butyl substituents, were synthesized by the alkylation of 2-tert-butyl-4-methylphenol with camphene and 2-isobornylphenol with tert-butyl chloride in the presence of acidic heterogeneous catalysts, montmorillonite KSF and FIBAN K-1. Antioxidant activity of the synthesized terpenophenols was evaluated using spectrophotometry.