5-chloro-[1,1'-biphenyl]-2,2'-diol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-chloro-[1,1'-biphenyl]-2,2'-diol
• 英文别名: 5-chlorobiphenyl-2,2'-diol；5-Chloro-2,2'-dihydroxybiphenyl；4-chloro-2-(2-hydroxyphenyl)phenol
• 化学式: C₁₂H₉ClO₂
• 分子量: 220.655
• InChiKey: HNOJZMVRVOWZOD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-氯二苯并-对-二恶英 在 氧气 作用下， 以 甲醇 为溶剂， 反应 0.08h， 以28.8%的产率得到5-chloro-[1,1'-biphenyl]-2,2'-diol
  参考文献：
  名称：

  氯化二苯并对二恶英的光化学重排。单重激发态的区域选择性碳-氧键均裂和三重激发态的碳-氯键均裂

  摘要：

  甲醇中的 1-氯-、2-氯-、1,2-二氯-、2,3-二氯-和 2,7-二氯二苯并-对-二恶英的紫外光照射导致碳-氧键的区域选择性均裂单线态排除...

  DOI：

  10.1246/cl.2006.348

文献信息

• Synthesis of 2,2′-biphenols through direct C(sp²)–H hydroxylation of [1,1′-biphenyl]-2-ols
  作者：Shitao Duan、Yuanshuang Xu、Xinying Zhang、Xuesen Fan

  DOI：10.1039/c6cc04756d

  日期：——

  A novel synthesis of diversely substituted 2,2′-biphenols through Pd(ii)-catalyzed,^tBuOOH-oxidized, and hydroxyl-directed C(sp²)–H hydroxylation of [1,1′-biphenyl]-2-ols has been developed.

  通过Pd（II）催化，tBuOOH氧化和羟基引导的[1,1′-联苯基]-2-醇的C(sp2)–H羟基化反应，已经开发出了一种新的合成方法，可以合成各种取代的2,2′-联苯酚。
• 2,2′-Biphenols via Protecting Group-Free Thermal or Microwave-Accelerated Suzuki–Miyaura Coupling in Water
  作者：Bernd Schmidt、Martin Riemer、Manfred Karras

  DOI：10.1021/jo401398n

  日期：2013.9.6

  User-friendly protocols for the protecting group-free synthesis of 2,2'-biphenols via Suzuki-Miyaura coupling of o-halophenols and o-boronophenol are presented. The reactions proceed in water in the presence of simple additives such as K2CO3, KOH, KF, or TBAF and with commercially available Pd/C as precatalyst. Expensive or laboriously synthesized ligands or other additives are not required. In the case of bromophenols, efficient rate acceleration and short reaction times were accomplished by microwave irradiation.
• APPLICATION OF BISPHENOL SALT IN PREPARING DISINFECTANT USED FOR STERILIZATION OR FORMALDEHYDE REMOVAL
  申请人：NINGBO YUCHEN ENVIROCLEAN TECH CO., LTD.

  公开号：US20160198705A1

  公开（公告）日：2016-07-14

  The present invention relates to an application of bisphenol salts in preparing a disinfectant used for sterilization or formaldehyde removal. The present invention provides a sterilization and disinfection system that uses oxygen in the air as oxidizer, kills microorganisms via catalyzed oxidation, and is particularly suitable in an air purification system. The disinfectant of the present invention can be used for an extended period of time insofar that air is continuously introduced, obviates the need for an anti-viral agent, also obviates the need for a peroxide that is potentially hazardous to safety, uses no halogen-containing irritating substance, and use no alcohol having risk of explosion. This disinfectant system that uses no precious metal is easy to prepare, low in use cost, and free of secondary pollution, and provides a good application prospect.
• Photochemical Rearrangement of Chlorinated Dibenzo-<i>p</i>-dioxins. Regioselective Carbon–Oxygen Bond Homolysis from the Singlet Excited State, and Carbon–Chlorine Bond Homolysis from the Triplet Excited State
  作者：Takanori Kobayashi、Jun-ichi Shimada、Chieko Kitahara、Naoki Haga

  DOI：10.1246/cl.2006.348

  日期：2006.4

  UV light irradiation of 1-chloro-, 2-chloro-, 1,2-dichloro-, 2,3-dichloro-, and 2,7-dichlorodibenzo-p-dioxin in methanol leads to regioselective homolysis of carbon–oxygen bond from the singlet exc...

  甲醇中的 1-氯-、2-氯-、1,2-二氯-、2,3-二氯-和 2,7-二氯二苯并-对-二恶英的紫外光照射导致碳-氧键的区域选择性均裂单线态排除...