Dibenzyldichlorosilane appears as a clear to light yellow liquid. Insoluble in water and less dense than water. Contact may severely irritate skin, eyes and mucous membranes. May be toxic by ingestion, inhalation and skin absorption. Used to make other chemicals.
分解：
The silanes decomp at elevated temp to liberate hydrogen and deposit a high purity silicon, which leads to some of the principal uses of silanes. /Silanes/
腐蚀性：
Corrosive
计算性质
辛醇/水分配系数(LogP)：
4.47
重原子数：
17
可旋转键数：
4
环数：
2.0
sp3杂化的碳原子比例：
0.14
拓扑面积：
0
氢给体数：
0
氢受体数：
0
ADMET
代谢
氯硅烷在与组织液接触时，会迅速水解释放氯化氢。
... Chlorosilanes will be rapidly hydrolyzed upon contact with tissue fluids to release hydrochloric acid. /Chlorosilanes/
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Silane, Chlorosilane, and Related Compounds/
Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Anticipate seizures and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal (refer to ingestion protocol in Section Three ... . Cover skin burns with sterile dressings after decontamination ... . /Silane, Chlorosilane, and Related Compounds/
Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Early intubation at the first sign of upper airway obstruction may be necessary. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Silane, Chlorosilane, and related compounds/
/SIGNS AND SYMPTOMS/ Acute inhalation exposure may result in sneezing, choking, laryngitis, dyspnea (shortness of breath), respiratory tract irritation, and chest pain. Higher exposure can cause pulmonary edema, a medical emergency that can be delayed for several hours. This can cause death. Bleeding of nose and gums, ulceration of the nasal and oral mucosa, pulmonary edema, chronic bronchitis, and pneumonia may also occur. If the eyes have come in contact with dimethyldichlorosilane, irritation, pain, swelling, corneal erosion, and blindness may result. Dermatitis (red, inflamed skin), severe burns, pain, and shock generally follow dermal exposure. Inhalation irritates mucous membranes. Severe gastrointestinal damage may occur. Vapors cause severe eye and lung injury. Upon short contact, second and third degree burns may occur. Signs and symptoms of acute ingestion of dimethyldichlorosilane may be severe and include increased salivation, intense thirst, difficulty swallowing, chills, pain, and shock. Oral, esophageal, and stomach burns are common. /Dimethyldichlorosilane/
/SIGNS AND SYMPTOMS/ Inhalation irritates mucous membranes. Contact with liq causes severe burns of eyes and skin ... Vapors cause severe irritation of eyes and throat and can cause eye and lung injury. They cannot be tolerated even at low concn. Causes second- and third-degree burns on short contact ...
New Insights into Hexacoordinated Silicon Complexes with 8- Oxyquinolinato Ligands: 1,3-Shift of Si-Bound Hydrocarbyl Substituents and the Influence of Si-Bound Halides on the 8-Oxyquinolinate Coordination Features
New Insights into Hexacoordinated Silicon Complexes with 8- Oxyquinolinato Ligands: 1,3-Shift of Si-Bound Hydrocarbyl Substituents and the Influence of Si-Bound Halides on the 8-Oxyquinolinate Coordination Features
six-membered chelate is formed by the dianion, and smaller rings are not present in the compound), the poor electron withdrawal from silicon by its C– or H– substituents and the flexible methylene bridge between the salicylamide and the pyridine moiety, the pyridine N donoratom furnishes pentacoordinate silicon coordination spheres in all of these compounds 2a–2f. The coordination number of the silicon atom
Novel Aryl Substituted Silanes Part I: Synthesis and Characterization of Diaryl Silicon Dichlorides
作者：Judith Binder、Roland C. Fischer、Michaela Flock、Ana Torvisco、Frank Uhlig
DOI：10.1080/10426507.2015.1049744
日期：2015.11.2
GRAPHICAL ABSTRACT Abstract A series of novel and previously published silicon dichlorides, R2SiCl2 (R = benzyl, fluorenyl, p-tolyl p-n-butyl, p-biphenyl, m-tolyl, o-tolyl, 2,4-xylyl, 2,6-xylyl, p-biphenyl, 1-naphthyl, 9-anthracenyl), were synthesized and characterized using 1H-, 13C- and 29Si NMR spectroscopy. Effects of substituent bulk on both experimental and calculated 29Si NMR shifts are compared
Novel aryl-substituted silanes Part II: Synthesis and characterization of diaryl silicon dihydrides
作者：Judith Binder、Roland C. Fischer、Michaela Flock、Hans-Georg Stammler、Ana Torvisco、Frank Uhlig
DOI：10.1080/10426507.2015.1094657
日期：2016.3.3
GRAPHICAL ABSTRACT ABSTRACT A series of novel and previously published silicon dihydrides, R2SiH2 (R = benzyl, fluorenyl, p-tolyl, p-n-butyl, p-biphenyl, m-tolyl, o-tolyl, 2,4-xylyl, 2,6-xylyl, p-biphenyl, 1-naphthyl, 9-anthracenyl), were synthesized and characterized using 1H, 13C, and 29Si NMR spectroscopy. Effects of substituent bulk on 29Si NMR shifts are compared between reported silicon dihydrides
