bicyclo[2.2.1]hept-2-ene-5,6-dicarboxylic acid | 3853-88-1

• 物质功能分类: 化学试剂 - 有机试剂 - 脂肪酸
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: bicyclo[2.2.1]hept-2-ene-5,6-dicarboxylic acid
• 英文别名: norborn-5-ene-2,3-dicarboxylic acid；5-norbornene-2,3-dicarboxylic acid；bicyclo[2.2.1]hept-5-ene-2-endo,3-exo-dicarboxylic acid；5-norbornene-2-endo-3-exodicarboxylic acid；Cis-bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid；(1R,4S)-bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid
• CAS: 3853-88-1
• 化学式: C₉H₁₀O₄
• 分子量: 182.176
• InChiKey: NIDNOXCRFUCAKQ-DPTVFECHSA-N

物化性质

• 熔点：
  175 °C (dec.)(lit.)
• 沸点：
  419.8±45.0 °C(Predicted)
• 密度：
  1.481±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 危险等级：
  IRRITANT
• 危险品标志：
  Xn
• 安全说明：
  S26,S37/39
• 危险类别码：
  R20/21/22,R36/37/38
• WGK Germany：
  3
• 海关编码：
  2917209090
• 危险性防范说明：
  P261,P280,P305+P351+P338
• 危险性描述：
  H302+H312+H332,H315,H319,H335

反应信息

• 作为反应物：
  描述：

  bicyclo[2.2.1]hept-2-ene-5,6-dicarboxylic acid 在 四磷十氧化物 、 氨 作用下， 305.0 ℃ 、5.0 kPa 条件下， 反应 1.5h， 生成 5-norbornene-2,3-dicarbonitrile
  参考文献：
  名称：

  腈及其相应胺的制造方法

  摘要：

  本发明涉及一种腈的制造方法，与现有技术相比，具有氨源用量显著降低、环境压力小、能耗低、生产成本低、腈产品的纯度和收率高等特点，并且能够获得结构更为复杂的腈。本发明还涉及由该腈制造相应胺的方法。

  公开号：

  CN105016942B

文献信息

• Synthesis and Properties of a pH-Insensitive Fluorescent Nitric Oxide Cheletropic Trap (FNOCT)
  作者：Frank Stefan Hornig、Hans-Gert Korth、Ursula Rauen、Herbert de Groot、Reiner Sustmann

  DOI：10.1002/hlca.200690212

  日期：2006.10

  The synthesis and properties of the new fluorescent nitric oxide cheletropic trap (FNOCT) 14, designed for the trapping and quantification of nitric oxide (NO) production in chemical and biological systems, is described (Scheme 3). The dicarboxylic acid 14 and the corresponding bis[(acetyloxy)methyl] ester derivative 15 of the FNOCT contain a 2-methoxy-substituted phenanthrene group as fluorophoric

  描述了设计用于化学和生物系统中一氧化氮（NO）产量的捕集和定量的新型荧光一氧化氮趋向性捕集器（FNOCT）14的合成和性质（方案3）。FNOCT的二羧酸14和相应的双[（乙酰氧基）甲基]酯衍生物15含有2-甲氧基取代的菲基团作为荧光团单元。此FNOCT的降低NO加合物的荧光（λ EXC 320纳米，λ EM380 nm）是pH无关的。在pH 7.4的缓冲水溶液中进行诱捕实验，一氧化氮作为大剂量添加并从NO供体化合物MAHMA NONOate（=（1 Z）-1- methyl [6-（methylammonio）hexyl） ]氨基}二重氮-1-（1,2-二醇）酸酯，表明捕集效率约为。50％。在生物学应用中，从脂多糖刺激的大鼠肺泡巨噬细胞培养物中清除了一氧化氮。在所施加的条件下，每小时和每10 5个细胞的NO产生量估计为11.1±1.5 nmol 。
• THERMOPLASTIC POLYMER HAVING POLAR GROUP, USE THEREOF, AND UNSATURATED COMPOUNDS HAVING POLAR GROUP
  申请人：Mitsui Chemicals, Inc.

  公开号：EP1197504A1

  公开（公告）日：2002-04-17

  The present invention is intended to provide a polar group-containing thermoplastic polymer having high adhesion to metals and polar polymers, uses thereof and a polar group-containing unsaturated compound. The polar group-containing thermoplastic polymer is one obtained by graft modifying a thermoplastic polymer with at least one kind of a polar group-containing unsaturated compound represented by the following formula (I):         A-X-R2-(Y)p-R1     (I) wherein A is a group containing a double bond, X is -COO-, -OCO-, -CO-, -O- or the like, R2 is a divalent group containing a carbon atom or a single bond, Y is -CO-, -COO-, -OCO-, -O- or the like, p is 0 or 1, R1 is a polar group selected from a carboxylic anhydride group, an epoxy group and the like or an alkyl, cycloalkyl or aryl group containing a polar group, and the bond chain linking the double bond in A to the polar group in R1 is constituted of 6 or more atoms.

  本发明旨在提供一种含极性基团的热塑性聚合物，具有对金属和极性聚合物的高粘附性，以及其用途和含极性基团的不饱和化合物。所述含极性基团的热塑性聚合物是通过将至少一种由以下式（I）表示的含极性基团的不饱和化合物进行接枝改性而获得的：        A-X-R2-(Y)p-R1     （I）其中A是含有双键的基团，X是-COO-，-OCO-，-CO-，-O-或类似的基团，R2是含有碳原子或单键的二价基团，Y是-CO-，-COO-，-OCO-，-O-或类似的基团，p为0或1，R1是从羧酸酐基团、环氧基团等中选择的极性基团，或含有极性基团的烷基、环烷基或芳基，A中的双键与R1中的极性基团之间的键链由6个或更多原子构成。
• Olefin block copolymers processes for producing the same and uses thereof
  申请人：——

  公开号：US20030055179A1

  公开（公告）日：2003-03-20

  The present invention provides polymers having any one of properties including affinity for metals or polar resins, impact resistance, mar resistance, heat resistance, rigidity, oil resistance, transparency, anti-fogging properties, electric insulating properties, high breakdown voltage, coating properties, low-temperature flexibility, moldability, environmental degradation, fluidity and dispersibility, and provides a process for preparation thereof. The olefin block copolymers (A-1) of the invention are represented by the formula (I) PO 1 —g 1 —B 1 (I) (wherein PO 1 is a segment composed of repeating units derived from an olefin having 2 to 20 carbon atoms, g 1 is an ester, ether, amide, imide, urethane, urea, silylether or carbonyl linkage, and B 1 is a segment containing an unsaturated hydrocarbon or a hetero atom). The olefin block copolymers are suitable for uses in adhesives; various molded articles such as construction and civil engineering materials, automobile interior and exterior materials, gasoline tanks, electric and electronic parts, medical care and sanitation materials, materials of miscellaneous goods, resin materials having environmental degradation properties, films and sheets; modifiers and dispersions.

  本发明提供了具有以下任一性质的聚合物，包括对金属或极性树脂的亲和性，抗冲击性，抗刮伤性，耐热性，刚度，耐油性，透明性，防雾性能，电绝缘性能，高击穿电压，涂料性能，低温柔性，可塑性，环境降解性，流动性和分散性，并提供其制备方法。本发明的烯烃嵌段共聚物（A-1）由公式（I）表示：PO1-g1-B1（I）（其中PO1是由具有2至20个碳原子的烯烃衍生的重复单元组成的片段，g1是酯，醚，酰胺，亚胺，脲，硅醚或羰基连接，B1是含有不饱和碳氢化合物或杂原子的片段）。烯烃嵌段共聚物适用于粘合剂；各种成型品，如建筑和土木工程材料，汽车内外饰料，汽油箱，电子和电气零件，医疗保健和卫生材料，杂货物料，具有环境降解性能的树脂材料，薄膜和片材；改性剂和分散剂。
• Insulating material containing cycloolefin polymer
  申请人：——

  公开号：US20040157039A1

  公开（公告）日：2004-08-12

  An insulating material comprising a cycloolefin polymer, specifically, an interlayer insulating material for a high-density assembly board having interlayer-connecting via holes at most 200 &mgr;m in diameter, comprising a cycloolefin polymer containing at least 50 mol % of a repeating unit derived from a cycloolefin monomer; a dry film formed from a curable resin composition comprising a polymer having a number average molecular weight within a range of 1,000 to 1,000,000 as measured by gel permeation chromatography, and a hardener; and a resin-attached metal foil obtained by forming a film of a cycloolefin polymer on one side of a metal foil. Laminates, multi-layer laminates and build-up multi-layer laminates making use of these materials, and production processes thereof.

  一种绝缘材料，包括环氧烷基聚合物，具体地说，这是一种用于高密度组装板的层间绝缘材料，其间层连接的经孔直径最多为200微米，包括至少50摩尔％来自环氧烷基单体的重复单元的环氧烷基聚合物; 由可固化树脂组成的可干膜，其聚合物的数量平均分子量在1,000至1,000,000之间（通过凝胶渗透色谱法测量），以及硬化剂; 以及通过在金属箔的一侧形成环氧烷基聚合物膜而获得的树脂附着金属箔。利用这些材料制成的层压板，多层层压板和堆叠多层层压板以及其生产工艺。
• Propylene resin composition and use thereof
  申请人：Hoya Hiroshi

  公开号：US20070251572A1

  公开（公告）日：2007-11-01

  The thermoplastic resin composition (Xi) of the present invention comprises (A1), (B1), (C1), and optionally (D1) below: 1 to 90 wt % of an isotactic polypropylene (A1); 9 to 98 wt % of a propylene/ethylene/α-olefin copolymer (B1) containing 45 to 89 mol% of propylene-derived structural units, 10 to 25 molt of ethylene-derived structural units, and optionally, 0 to 30 mol% of C 4 -C 20 α-olefin-derived structural units (a1); 1 to 80 wt % of a styrene-based elastomer (C1); and 0 to 70 wt % of an ethylene/α-olefin copolymer (D1) whose density is in the range of 0.850 to 0.910 g/cm 3 , wherein (A1)+(B1)+(C1)+(D1)=100 wt %.

  本发明的热塑性树脂组合物（Xi）包括以下成分（A1）、（B1）、（C1）和可选的（D1）：1至90重量％的异相聚丙烯（A1）; 9至98重量％的丙烯/乙烯/α-烯烃共聚物（B1），其中含有45至89摩尔％的丙烯衍生结构单元，10至25摩尔％的乙烯衍生结构单元，以及可选地0至30摩尔％的C4-C20α-烯烃衍生结构单元（a1）; 1至80重量％的苯乙烯弹性体（C1）; 以及密度在0.850至0.910 g/cm3范围内的乙烯/α-烯烃共聚物（D1），其中（A1）+（B1）+（C1）+（D1）= 100重量％。