二苯基十三烷 | 97392-73-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 二苯基十三烷
• 中文别名: 5-氯-2-羟基-N-(2,4,5-三氯苯基)联苯基-3-甲酰胺
• 英文名称: tridecane-1,1-diyldibenzene
• 英文别名: Diphenyltridecane；1-phenyltridecylbenzene
• CAS: 97392-73-9
• 化学式: C₂₅H₃₆
• 分子量: 336.561
• InChiKey: REGVVWIVILJTIW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.1
• 重原子数：
  25
• 可旋转键数：
  13
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  苯乙烯 、 过氧化双月桂酰 、 苯硼酸 在 tetrakis(actonitrile)copper(I) hexafluorophosphate 、 (S,S)-2,6-双(4-异丙基-2-恶唑啉-2-基)吡啶 、 N,N-二异丙基乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 12.0h， 以74%的产率得到二苯基十三烷
  参考文献：
  名称：

  Cu-Catalyzed Alkylarylation of Vinylarenes with Masked Alkyl Electrophiles

  摘要：

  A Cu-catalyzed synthesis of a range of value-added 1,1-diarylalkanes by radical alkylarylation of vinylarenes with alkyl peroxides as masked alkyl electrophiles is reported. The reaction features broad substrate scope, good functional group tolerance, and mild reaction conditions. Various bioactive molecules and key pharmaceutical intermediates have been easily synthesized by this method, demonstrating its synthetic value.

  DOI：

  10.1021/acs.orglett.9b04392

文献信息

• Cu-Catalyzed Alkylarylation of Vinylarenes with Masked Alkyl Electrophiles
  作者：Xiaotao Zhu、Muqiao Su、Qi Zhang、Yajun Li、Hongli Bao

  DOI：10.1021/acs.orglett.9b04392

  日期：2020.1.17

  A Cu-catalyzed synthesis of a range of value-added 1,1-diarylalkanes by radical alkylarylation of vinylarenes with alkyl peroxides as masked alkyl electrophiles is reported. The reaction features broad substrate scope, good functional group tolerance, and mild reaction conditions. Various bioactive molecules and key pharmaceutical intermediates have been easily synthesized by this method, demonstrating its synthetic value.