3-(methoxycarbonyl-phenyl-methylsulfanylthiocarbonylsulfanyl)propionic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(methoxycarbonyl-phenyl-methylsulfanylthiocarbonylsulfanyl)propionic acid
• 英文别名: 3-(2-Methoxy-2-oxo-1-phenylethyl)sulfanylcarbothioylsulfanylpropanoic acid
• 化学式: C₁₃H₁₄O₄S₃
• 分子量: 330.45
• InChiKey: DLRFJCVOBACVOZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  20
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  146
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  二硫化碳 、 α-溴苯乙酸甲酯 、 3-巯基丙酸 在 氢氧化钾 作用下， 以 水 为溶剂， 反应 17.0h， 生成 3-(methoxycarbonyl-phenyl-methylsulfanylthiocarbonylsulfanyl)propionic acid
  参考文献：
  名称：

  Merrifield Resin-Supported Chain Transfer Agents, Precursors for RAFT Polymerization

  摘要：

  [GRAPHICS]The modification of Merrifield resins to form chain transfer agent (CTA) precursors for reversible addition fragmentation chain transfer (RAFT) polymerization is investigated. A series of CTA precursor resins were prepared and characterized by FTIR and elemental analysis (EA).

  DOI：

  10.1021/ol051078t

文献信息

• POLYMERISATION USING CHAIN TRANSFER AGENTS
  申请人：Perrier Sebastian

  公开号：US20090215965A1

  公开（公告）日：2009-08-27

  The invention provides a process for synthesising functionalised chain transfer polymers of Formula (1) or Formula (2) using thiocarbonyl thio compounds as chain transfer agents. Why R1 is a moiety comprising a functional group; Q is obtained from an olefinically unsaturated monomer; R′ is selected from the group consisting of alkyl, substituted alkyl, alkoxy, substituted alkoxy, an aromatic saturated or unsaturated carbocyclic or heterocyclic ring, optionally substituted with one or more substituents, amino alkyl, cyanoalkyl, hydroxylalkyl, saturated and unsaturated amido; an organometallic species, a polymer chain and any of the foregoing substituted with one or more CN or OH groups; q=an integer of at least 2; p=an integer of at least 1. Chain transfer agents and polymers produced by the method are also provided.

  该发明提供了一种合成功能化链转移聚合物的方法，使用硫代羰基硫化合物作为链转移剂，其化学式为(1)或(2)。其中，R1是包含功能基团的基团；Q是从烯烃不饱和单体获得的；R′选自包括烷基、取代烷基、烷氧基、取代烷氧基、芳香饱和或不饱和碳环或杂环环，可选地取代一个或多个取代基，氨基烷基、氰基烷基、羟基烷基、饱和和不饱和酰胺的基团；有机金属物种、聚合物链和上述任何一种基团，其中取代有一个或多个CN或OH基团；q至少为2的整数；p至少为1的整数。该方法还提供了链转移剂和由该方法产生的聚合物。
• Polymerisation Using Chain Transfer Agents
  申请人：Perrier Sebastien

  公开号：US20070299221A1

  公开（公告）日：2007-12-27

  The invention provides a process for synthesising functionalised chain transfer polymers of Formula (1) or Formula (2) using thiocarbonyl thio compounds as chain transfer agents. Why R1 is a moiety comprising a functional group; Q is obtained from an olefinically unsaturated monomer; R′ is selected from the group consisting of alkyl, substituted alkyl, alkoxy, substituted alkoxy, an aromatic saturated or unsaturated carbocyclic or heterocyclic ring, optionally substituted with one or more substituents, amino alkyl, cyanoalkyl, hydroxylalkyl, saturated and unsaturated amido; an organometallic species, a polymer chain and any of the foregoing substituted with one or more CN or OH groups; q=an integer of at least 2; p=an integer of at least 1. Chain transfer agents and polymers produced by the method are also provided.
• [EN] POLYMERISATION USING CHAIN TRANSFER AGENTS<br/>[FR] POLYMERISATION EFFECTUEE A L'AIDE D'AGENTS DE TRANSFERT DE CHAINE
  申请人：UNIV LEEDS

  公开号：WO2005061555A1

  公开（公告）日：2005-07-07

  The invention provides a process for synthesising functionalised chain transfer polymers of Formula (1) or Formula (2) using thiocarbonyl thio compounds as chain transfer agents. Why R1 is a moiety comprising a functional group; Q is obtained from an olefinically unsaturated monomer; R’ is selected from the group consisting of alkyl, substituted alkyl, alkoxy, substituted alkoxy, an aromatic saturated or unsaturated carbocyclic or heterocyclic ring, optionally substituted with one or more substituents, amino alkyl, cyanoalkyl, hydroxylalkyl, saturated and unsaturated amido; an organometallic species, a polymer chain and any of the foregoing substituted with one or more CN or OH groups; q = an integer of at least 2; p = an integer of at least 1. Chain transfer agents and polymers produced by the method are also provided.
• Merrifield Resin-Supported Chain Transfer Agents, Precursors for RAFT Polymerization
  作者：Pittaya Takolpuckdee、Craig A. Mars、Sébastien Perrier

  DOI：10.1021/ol051078t

  日期：2005.8.1

  [GRAPHICS]The modification of Merrifield resins to form chain transfer agent (CTA) precursors for reversible addition fragmentation chain transfer (RAFT) polymerization is investigated. A series of CTA precursor resins were prepared and characterized by FTIR and elemental analysis (EA).