O-(2-methoxy-ethyl)-lactic acid | 200617-09-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: O-(2-methoxy-ethyl)-lactic acid
• 英文别名: 2-(2-Methoxy-aethoxy)-propionsaeure；O-(2-Methoxy-aethyl)-milchsaeure；2-methyl-3,6-dioxaheptanoic acid；2-(2-methoxyethoxy)propanoic Acid
• CAS: 200617-09-0
• 化学式: C₆H₁₂O₄
• mdl: MFCD09931004
• 分子量: 148.159
• InChiKey: JIXHYWCLUOGIMM-UHFFFAOYSA-N

物化性质

• 沸点：
  255.9±15.0 °C(Predicted)
• 密度：
  1.095±0.06 g/cm3(Predicted)
• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.833
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  甲氧基乙醇钠 、 2-溴丙酸 生成 O-(2-methoxy-ethyl)-lactic acid
  参考文献：
  名称：

  Palomaa; Jaervenkylae, Chemische Berichte, 1932, vol. 65, p. 923

  摘要：

  DOI：

文献信息

• PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO
  申请人：Crouse Gary D.

  公开号：US20120202687A1

  公开（公告）日：2012-08-09

  This document discloses molecules having the following formulas (“Formula One” & “Formula Two” and “Formula Three”) The Ar 1 , Het, Ar 2 , R1, R2, R3, R4, and R5 are further described herein.

  这份文件披露了具有以下化学式的分子（“化学式一”和“化学式二”和“化学式三”）。Ar1、Het、Ar2、R1、R2、R3、R4和R5在此进一步描述。
• Chemical amplification type resist composition
  申请人：Yamada Airi

  公开号：US20080269506A1

  公开（公告）日：2008-10-30

  The present invention provides a sulfonium salt of the formula (Ia) a polymeric compound comprising a structural unit of the formula (Ib) and a chemical amplification type positive resist composition comprising (A) an acid generator comprising at least one compound selected from the group consisting of a sulfonium salt of the formula (Ia), a polymeric compound comprising a structural unit of the formula (Ib), and a sulfonium salt of the formula (Ic); and (B) resin which contains a structural unit having an acid labile group and which itself is insoluble or poorly soluble in an alkali aqueous solution but becomes soluble in an alkali aqueous solution by the action of an acid.

  本发明提供了一种公式(Ia)的硫鎓盐，包括一个结构单元的聚合物化合物的公式(Ib)，以及一种化学放大型正性光刻胶组合物，包括(A)至少选择自硫鎓盐的公式(Ia)、一个结构单元的聚合物化合物的公式(Ib)和硫鎓盐的公式(Ic)组成的酸发生剂；以及(B)含有酸敏感基团的结构单元的树脂，本身在碱性水溶液中不溶或难溶，但在酸的作用下变得可溶于碱性水溶液。
• ONIUM SALT, LIQUID COMPOSITION CONTAINING SAID ONIUM SALT AND CELLULOSE, AND CELLULOSE RECOVERY METHOD
  申请人：KOEI CHEMICAL COMPANY, LIMITED

  公开号：US20160009669A1

  公开（公告）日：2016-01-14

  The invention relates to an onium salt, a liquid composition containing the onium salt and cellulose, and a method for recovering cellulose. The invention makes it possible to provide an onium salt having an extremely high ability to dissolve cellulose at temperatures of 100° C. or lower. It also makes it possible to provide a liquid composition containing this onium salt and cellulose, as a composition suitable for the recovery of cellulose, and a method for recovering cellulose efficiently by using such a liquid composition containing the onium salt and cellulose.

  该发明涉及一种含有onium盐和纤维素的液体组合物以及一种恢复纤维素的方法。该发明使得能够在100°C或更低温度下提供具有极高溶解纤维素能力的onium盐成为可能。它还使得能够提供一种含有该onium盐和纤维素的液体组合物，作为适用于纤维素恢复的组合物，并通过使用含有onium盐和纤维素的这种液体组合物高效地恢复纤维素的方法成为可能。
• [EN] NOVEL PYRAZOLO PYRIMIDINE DERIVATIVES AND THEIR USE AS MALT1 INHIBITORS<br/>[FR] NOUVEAUX DÉRIVÉS PYRAZOLO-PYRIMIDINE ET LEUR UTILISATION COMME INHIBITEURS DE MALT1
  申请人：NOVARTIS AG

  公开号：WO2015181747A1

  公开（公告）日：2015-12-03

  The present invention describes new pyrazolo-pyrimidine derivatives of formula (I) or a pharmaceutically acceptable salt thereof; (I) wherein, R1 is halogen, cyano, or C1-C3alkyl optionally substituted by halogen; R2 is C1-C6alkyl optionally substituted one or more times by C1-C6alkyl, C2-C6alkenyl, hydroxyl, N,N-di-C1-C6alkyl amino, N-mono-C1-C6alkyl amino, O-Rg, Rg, phenyl, or by C1-C6alkoxy wherein said alkoxy again may optionally be substituted by C1-C6alkoxy, N,N-di-C1-C6alkyl amino, Rg or phenyl; C3-C6cycloalkyl optionally substituted by C1-C6alkyl, N,N-di-C1-C6alkyl amino or C1-C6alkoxy-C1-C6alkyl, and/or two of said optional substituents together with the atoms to which they are bound may form an annulated or spirocyclic 4 - 6 membered saturated heterocyclic ring comprising 1 - 2 O atoms; phenyl optionally substituted by C1-C6alkoxy; a 5 - 6 membered heteroaryl ring having 1 to 3 heteroatoms selected from N and O said ring being optionally substituted by C1-C6alkyl which may be optionally substituted by amino or hydroxy; Rg; or N,N-di-C1-C6alkyl amino carbonyl; and R is phenyl independently substituted two or more times by Ra, 2-pyridyl independently substituted one or more times by Rb, 3-pyridyl independently substituted one or more times by Rc, or 4-pyridyl independently substituted one or more times by Rd; which are generally interacting with MALT1 proteolytic and/or autoproteolytic activity, and in particular which may inhibit said activity. The present invention further describes the synthesis of said new pyrazolo-pyrimidine derivatives, their use as a medicament, especially by interacting with MALT1 proteolytic and/or autoproteolytic activity.

  本发明描述了新的吡唑基嘧啶衍生物（I）或其药学上可接受的盐；（I）其中，R1是卤素、氰基或由卤素取代的C1-C3烷基；R2是C1-C6烷基，可选地由C1-C6烷基、C2-C6烯基、羟基、N,N-二C1-C6烷基氨基、N-单C1-C6烷基氨基、O-Rg、Rg、苯基或由C1-C6烷氧基取代的C1-C6烷基取代一次或多次，其中该烷氧基再次可选地由C1-C6烷氧基、N,N-二C1-C6烷基氨基、Rg或苯基取代；C3-C6环烷基，可选地由C1-C6烷基、N,N-二C1-C6烷基氨基或C1-C6烷氧基-C1-C6烷基取代，和/或两个可选取代基与它们连接的原子一起可以形成1-2个氧原子的环化或螺环4-6成员饱和杂环环，包括苯基，可选地由C1-C6烷氧基取代；具有1至3个异原子（N和O）的5-6成员杂环环，该环可选地由C1-C6烷基取代，该烷基可选地由氨基或羟基取代；Rg；或N,N-二C1-C6烷基氨基羰基；R独立地由Ra取代两次或两次以上，独立地由Rb取代一次或多次的2-吡啶基，独立地由Rc取代一次或多次的3-吡啶基，或独立地由Rd取代一次或多次的4-吡啶基；这些基本上与MALT1蛋白酶和/或自体蛋白酶活性相互作用，特别是可能抑制该活性。本发明进一步描述了所述新的吡唑基嘧啶衍生物的合成，它们作为药物的用途，特别是通过与MALT1蛋白酶和/或自体蛋白酶活性相互作用。
• Chemically amplified positive resist composition
  申请人：Takemoto Ichiki

  公开号：US20060160017A1

  公开（公告）日：2006-07-20

  The present invention provides a chemically amplified positive resist composition comprising (i) a polymer which is insoluble or poorly soluble in an alkali aqueous solution but becomes soluble in an alkali aqueous solution by the action of an acid, (ii) an acid generator, and (iii) a compound of the formula (I). The present invention also provides an ester derivative useful as a component of the chemically amplified positive resist composition, and process for producing the ester derivative.

  本发明提供了一种化学增感正性光刻胶组合物，包括(i)一种在碱性水溶液中不溶或难溶，但在酸的作用下变为可溶于碱性水溶液的聚合物，(ii)一种酸发生剂，以及(iii)式(I)的化合物。本发明还提供了一种酯衍生物，可用作化学增感正性光刻胶组合物的组分，以及制备酯衍生物的方法。