N'-(2-methyl-2-pentenylidene)acetohydrazide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N'-(2-methyl-2-pentenylidene)acetohydrazide
• 英文别名: N-[(E)-[(E)-2-methylpent-2-enylidene]amino]acetamide
• 化学式: C₈H₁₄N₂O
• 分子量: 154.212
• InChiKey: SJSUXAHRKPRYDK-PDTNFJSOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  41.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-methyl-2,5,8(1H)-quinolinetrione 、 N'-(2-methyl-2-pentenylidene)acetohydrazide 在 air 作用下， 以 xylene 为溶剂， 反应 23.0h， 以25%的产率得到6-ethyl-4,7-dimethyl-1H-pyrido[3,2-g]quinoline-2,5,10-trione
  参考文献：
  名称：

  1-Acylamino-1-azadienes as an alternative to 1-dimethylamino-1-azadienes in the preparation of 1,8-diazaanthracene-2,9,10-triones.

  摘要：

  Acetylhydrazones of alpha,beta-saturated aldehydes behave as 1-azadienes in their reaction with 2,5,8(1H)-quinolinetriones, affording 1,8-diazaanthracene-2,9,10-triones, while die corresponding N-methyl derivatives are unreactive. In comparison with N,N-dimethylhydrazones, acetylhydrazones are less reactive bur me yields obtained are similar or higher because of the suppression of side products formed by addition of dimethylamine to the starting quinone.

  DOI：

  10.1016/0040-4020(95)00295-j
• 作为产物：
  描述：

  2-甲基-2-戊烯醛 、 乙酰肼 以 乙醇 为溶剂， 反应 0.5h， 以93%的产率得到N'-(2-methyl-2-pentenylidene)acetohydrazide
  参考文献：
  名称：

  1-Acylamino-1-azadienes as an alternative to 1-dimethylamino-1-azadienes in the preparation of 1,8-diazaanthracene-2,9,10-triones.

  摘要：

  Acetylhydrazones of alpha,beta-saturated aldehydes behave as 1-azadienes in their reaction with 2,5,8(1H)-quinolinetriones, affording 1,8-diazaanthracene-2,9,10-triones, while die corresponding N-methyl derivatives are unreactive. In comparison with N,N-dimethylhydrazones, acetylhydrazones are less reactive bur me yields obtained are similar or higher because of the suppression of side products formed by addition of dimethylamine to the starting quinone.

  DOI：

  10.1016/0040-4020(95)00295-j