依法西泮 | 52042-01-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯二氮卓类
• 中文名称: 依法西泮
• 英文名称: 1-(β-Ethylsulfonylethyl)-5-(o-fluorophenyl)-7-chloro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
• 英文别名: Elfazepam；7-chloro-1-(2-ethylsulfonylethyl)-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-one
• CAS: 52042-01-0
• 化学式: C₁₉H₁₈ClFN₂O₃S
• 分子量: 408.881
• InChiKey: BSPSXMXQKZZNFP-UHFFFAOYSA-N

物化性质

• 沸点：
  666.4±55.0 °C(Predicted)
• 密度：
  1.37±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  75.2
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Diagnostic/therapeutic agents
  申请人：Klaveness Jo

  公开号：US20050002865A1

  公开（公告）日：2005-01-06

  Targetable diagnostic and/or therapeutically active agents, e.g. ultrasound contrast agents, comprising a suspension in an aqueous carrier liquid of a reporter comprising gas-containing or gas-generating material, said agent being capable of forming at least two types of binding pairs with a target.

  可定位的诊断和/或治疗活性剂，例如超声对比剂，包括悬浮在水载体液中的报告物，该报告物包含含气体或生成气体的材料，该剂能够与目标形成至少两种结合对。
• Dispenser comprising displaceable matrix with solid state properties
  申请人：ALZA CORPORATION

  公开号：EP0293066A2

  公开（公告）日：1988-11-30

  A dispenser is enclosed for delivering a beneficial agent to an environment of use. The dispenser comprising a wall that surrounds an internal space comprising a first means in the dispenser for changing from a dispenser state to an environment of use state on leaving the dispenser, a beneficial agent in the first means, and a second means in the dispenser for aiding in displacing the first means from the dispenser.

  封闭式分配器用于向使用环境输送有益药剂。分配器包括一个环绕内部空间的壁，其中包括分配器中的第一装置，用于在离开分配器时从分配器状态变为使用环境状态；第一装置中的有益药剂；以及分配器中的第二装置，用于帮助将第一装置从分配器中移出。
• Dispenser with dispersing member for delivering beneficial agent
  申请人：ALZA CORPORATION

  公开号：EP0297725A2

  公开（公告）日：1989-01-04

  A dispenser is disclosed for delivering a beneficial agent to an environment of use. The dispenser comprising a wall that surrounds an agent, push means for pushing the carrier means from the dispenser and fragmenting means for fragmenting the carrier as it is pushed from the dispenser.

  本发明公开了一种分配器，用于将有益药剂输送到使用环境中。分配器包括一个环绕药剂的壁、用于将载体从分配器中推出的推动装置和用于在载体从分配器中推出时将其破碎的破碎装置。
• Dispenser with movable matrix comprising a plurality of tiny pills
  申请人：ALZA CORPORATION

  公开号：EP0300623A2

  公开（公告）日：1989-01-25

  A dispenser is disclosed for delivering tiny pills to an environment of use. The dispenser comprising a wall that surrounds an internal space comprising a first mean in the dispenser for changing from a dispenser state to an environment of use state on leaving the dispenser, tiny pills in the first means, and a second means in the dispenser for aiding in displacing the first means for the dispenser.

  本发明公开了一种向使用环境输送小药丸的分配器。分配器包括一个环绕内部空间的壁，该内部空间包括分配器中的第一装置，用于在离开分配器时从分配器状态变为使用环境状态；第一装置中的小药丸；以及分配器中的第二装置，用于帮助分配器移位第一装置。
• CD38-BINDING CD31 PEPTIDES AND USES THEREOF
  申请人：ENCEFA

  公开号：EP3943505A1

  公开（公告）日：2022-01-26

  The present invention relates to peptides derived from CD31, specifically binding to CD38; and their use in the prevention and/or treatment of diseases.

  本发明涉及从 CD31 衍生的肽，特别是与 CD38 结合的肽；以及它们在预防和/或治疗疾病中的用途。