依西双溴丙脒 | 614-87-9

• 物质功能分类: 化学试剂 - 有机试剂 - 亚氨、脒
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: 依西双溴丙脒
• 中文别名: 依西双溴丙脒二羟乙基磺酸盐；伊西双溴丙脒
• 英文名称: Brolene
• 英文别名: 3,3'-dibromo-4,4'-propanediyldioxy-bis-benzamidine; bis-(2-hydroxy-ethane sulfonate-(1))；3,3'-Dibrom-4,4'-propandiyldioxy-bis-benzamidin; Bis-(2-hydroxy-aethan-sulfonat-(1))；dibrompropamidine isetionate；3-bromo-4-[3-(2-bromo-4-carbamimidoylphenoxy)propoxy]benzenecarboximidamide;2-hydroxyethanesulfonic acid
• CAS: 614-87-9
• 化学式: 2C₂H₆O₄S*C₁₇H₁₈Br₂N₄O₂
• 分子量: 722.43
• InChiKey: BZACJASHKPPTKX-UHFFFAOYSA-N

物化性质

• 熔点：
  226°

计算性质

• 辛醇/水分配系数(LogP)：
  2.49
• 重原子数：
  32
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  201
• 氢给体数：
  6
• 氢受体数：
  8

文献信息

• Method For Improved Bioactivation Of Pharmaceuticals
  申请人：Clement Bernd

  公开号：US20120077876A1

  公开（公告）日：2012-03-29

  This invention relates to a prodrug comprising a partial structure having the general formula (I) or (II), where R 1 and R 2 are hydrogen, alkyl, or aryl radicals.

  这项发明涉及一种前药，其包含具有一般式(I)或(II)的部分结构，其中R1和R2为氢、烷基或芳基基团。
• Polymer hydrogels for controlled release and absorption of biocides
  申请人：Densmore G. Crystal

  公开号：US20070128121A1

  公开（公告）日：2007-06-07

  A material that is capable of releasing an active agent in a controlled manner. The material includes a hydrogel vehicle and an active agent dispersed throughout the hydrogel. When brought into contact with an aqueous release media, the active agent is released from the hydrogel vehicle into the release media. Characteristics of the hydrogel, including composition and surface area, control the release of the agent. Methods of forming the material, dispensing the active agent, and removing the active agent from an aqueous solution are also described.

  一种能够以受控方式释放活性剂的材料。该材料包括水凝胶载体和分散在水凝胶中的活性剂。当与水溶液接触时，活性剂从水凝胶载体中释放到水溶液中。水凝胶的特性，包括组成和表面积，控制着活性剂的释放。还描述了制备该材料、分配活性剂和从水溶液中去除活性剂的方法。
• Improved compositions for treating infected burn wounds
  申请人：University of Strathclyde

  公开号：EP0125858A1

  公开（公告）日：1984-11-21

  A pharmaceutical composition comprises in admixture with a pharmaceutically acceptable vehicle or carrier, a therapeutically effective amount of a silver compound suitable for treating burns, preferably silver sulphadiazine, and a synergistic amount of dibromopropamidine or pharmaceutically acceptable salts thereof, preferably the isethionate or pamoate.

  一种药物组合物包括与药学上可接受的载体或载体、治疗有效量的适用于治疗烧伤的银化合物（最好是磺胺嘧啶银）以及增效量的二溴丙脒或其药学上可接受的盐（最好是异硫酸盐或帕莫酸盐）混合。
• Lavatory cleansing and sanitizing composition
  申请人：KIWI BRANDS INC

  公开号：EP0425463A2

  公开（公告）日：1991-05-02

  A phosphate-free liquid lavatory cleansing and sanitizing composition for use in a metering composition comprising a nonionic or anionic detergent-iodine complex, a nonionic or anionic surfactant in an amount to provide a monomer to micelle ratio of about 90:10 to 40:60, a water-soluble acid dye and water.

  一种用于计量组合物的无磷酸盐液体盥洗室清洁消毒组合物，由非离子或阴离子洗涤剂-碘复合物、非离子或阴离子表面活性剂（其用量可使单体与胶束的比例达到约 90:10 至 40:60）、水溶性酸染料和水组成。
• Toilet bowl cleaners containing iodophors
  申请人：KIWI BRANDS INC

  公开号：EP0423391A1

  公开（公告）日：1991-04-24

  Solid cake lavoratory cleansing block composition comprising an iodophor, polyethylene oxide polymer having a molecular weight between about 1 to 6 million, a dye, calcium sulfate and optional ingredients which include fragrances, binders, filler material and mixtures thereof.

  固体饼状香料清洁块组合物，包括碘伏、分子量在 100 万至 600 万之间的聚氧化乙烯聚合物、染料、硫酸钙和可选成分，其中包括香料、粘合剂、填充材料及其混合物。