1-[(2,2-dimethylpropyl)oxy]-3-(methyloxy)benzene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-[(2,2-dimethylpropyl)oxy]-3-(methyloxy)benzene
• 英文别名: 1-(2,2-Dimethylpropoxy)-3-methoxybenzene
• 化学式: C₁₂H₁₈O₂
• 分子量: 194.274
• InChiKey: PYHHUTZBKQRKAJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,3-二氟苯 在 N,N-二甲基丙烯基脲 、 potassium tert-butylate 作用下， 以 乙二醇二甲醚 、 甲苯 为溶剂， 反应 44.0h， 生成 1-[(2,2-dimethylpropyl)oxy]-3-(methyloxy)benzene
  参考文献：
  名称：

  Novel Synthesis of Desymmetrized Resorcinol Derivatives:  Aryl Fluoride Displacement on Deactivated Substrates

  摘要：

  A short, high-yielding synthesis of differentially substituted resorcinol derivatives has been developed that utilizes 1,3difluorobenzene as the starting material and employs sequential nucleophilic aromatic substitution (SNAr) reactions to generate desymmetrized products. The scope and limitations of the second SNAr reaction on the deactivated 1-alkoxy-3-fluorobenzene intermediates have been investigated. This methodology has also been employed in the synthesis of desymmetrized catechol derivatives from 1,2difluorobenzene.

  DOI：

  10.1021/jo0523868

文献信息

• Anti-Viral Compounds
  申请人：AbbVie Inc.

  公开号：US20170057981A1

  公开（公告）日：2017-03-02

  The present invention features compounds effective in inhibiting active against Hepatitis C virus (“HCV”) polymerase. The invention also features processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.

  该发明涉及对丙型肝炎病毒（“HCV”）聚合酶具有抑制活性的化合物。该发明还涉及制备这种化合物的方法，包含这种化合物的组合物以及使用这种化合物治疗HCV感染的方法。
• 10A-AZALIDE COMPOUND CROSSLINKED AT 10A- AND 12-POSITIONS
  申请人：Sugimoto Tomohiro

  公开号：US20110237784A1

  公开（公告）日：2011-09-29

  A novel 10a-azalide compound crosslinked at the 10a- and 12-positions, which is represented by the following formula, and is effective on even Hemophilus influenzae , or erythromycin resistant bacteria (e.g., resistant pneumococci and streptococci).

  一种新型的10a-azalide化合物，其在10a-和12-位置交联，化学式如下，并且对于Hemophilus influenzae，或者对红霉素产生耐药性的细菌（例如耐药性肺炎球菌和链球菌）具有有效性。
• INHIBITION OF THE FORMATION OF NITROSAMINES
  申请人：SOLVAY INTEROX

  公开号：EP0647216A1

  公开（公告）日：1995-04-12
• EP0647216A4
  申请人：——

  公开号：EP0647216A4

  公开（公告）日：1995-05-17
• SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION HAVING PHENYL GROUP-CONTAINING CHROMOPHORE
  申请人：NISSAN CHEMICAL INDUSTRIES, LTD.

  公开号：US20170146906A1

  公开（公告）日：2017-05-25

  The present invention provides a resist underlayer film-forming composition for lithography for forming a resist underlayer film that can be used as a hard mask with use of hydrolysis-condensation product of a hydrolyzable silane which also absorbs K.& laser. A resist underlayer film-forming composition for lithography comprising, as a silane, a hydrolyzable silane, a hydrolysis product thereof, or a hydrolysis-condensation product thereof, wherein the hydrolyzable silane includes a hydrolyzable silane of Formula (1): R 1 a R 2 b Si(R 3 ) 4−(a+b) Formula (1) [where R 1 is an organic group of Formula (2): and is bonded to a silicon atom through a Si−C bond; R 3 is an alkoxy group, an acyloxy group, or a halogen group; a is an integer of 1; b is an integer of 0 to 2; and a+b is an integer of 1 to 3], and a ratio of sulfur atoms to silicon atoms is 7% by mole or more in the whole of the silane. A resist underlayer film obtained by applying the resist underlayer film-forming composition onto a semiconductor substrate and baking it.