2,3-dimethyl-1,4-dioxocane-5,8-dione

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2,3-dimethyl-1,4-dioxocane-5,8-dione
• 英文别名: 2,3-dimethyl-1,4-dioxacyclooctane-5,8-dione
• 化学式: C₈H₁₂O₄
• 分子量: 172.181
• InChiKey: IHEOXPWZFCUHOQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  丁二酰氯 、 2,3-丁二醇 在 potassium chloride 、 三乙胺 作用下， 以 乙腈 为溶剂， 反应 14.0h， 以40%的产率得到2,3-dimethyl-1,4-dioxocane-5,8-dione
  参考文献：
  名称：

  一种环状化合物及其制备方法和应用

  摘要：

  本发明涉及一种式I所示的环状化合物及其制备方法和应用。本发明所述的环状化合物用于作为内给电子体化合物，可得到综合性能优良的烯烃聚合催化剂。特别是用于丙烯聚合时，催化剂的氢调敏感性好，所得聚合物的等规指数可调，所得聚丙烯树脂分子量分布宽。

  公开号：

  CN110950830B

文献信息

• The reaction of 1,3,2-dioxastannolans with diacyl chlorides: decarbonylation in the reaction with oxalyl chloride
  作者：Alwyn G. Davies、Pan Hua-De、Jalal A.-A. Hawari

  DOI：10.1016/s0022-328x(00)99202-7

  日期：1983.11

  2,2-Dibutyl-1,3,2-dioxastannolans react with carbonyl chloride to give the corresponding ethylene carbonates, and with malonyl chloride or succinyl chloride to give the oligomeric malonates or succinates. The reaction of oxalyl chloride, however, depends of the number of methyl substituents carried by the carbon atoms of the ring; with none, ethylene oxalate is essentially the only product, but increasing

  2,2-二丁基-1,3,2-二氧杂环戊烷与羰基氯反应生成相应的碳酸亚乙酯，并与丙二酰氯或琥珀酰氯反应生成低聚丙二酸酯或琥珀酸酯。然而，草酰氯的反应取决于环的碳原子所携带的甲基取代基的数目。没有任何一种，草酸乙烯酯基本上是唯一的产物，但是增加的甲基化会诱导一氧化碳的释放和碳酸亚乙酯的形成，直到有四个甲基取代基的只有频哪醇的碳酸盐，而没有草酸酯形成，这就是一个明显的例子。索普-英戈尔德效应的效果。讨论了该脱羰基的机理。
• POLYMER EXFOLIATED PHYLLOSILICATE NANOCOMPOSITE COMPOSITIONS AND A PROCESS FOR THE PREPARATION THEREOF
  申请人：Mallikarjuna Shroff Rama

  公开号：US20070191527A1

  公开（公告）日：2007-08-16

  The present invention provides a polymer-phyllosilicate nanocomposite composition comprising (a) 10-99.95% by weight of a matrix polymer and (b) 0.05-90% by weight of a phyllosilicate selected from the group consisting of hydrophilic synthetic phyllosilicates and natural phyllosilicates intercalated with a modifier, an alkylonium ion having reactive moiety. The phyllosilicate is substantially homogeneously dispersed and/or exfoliated throughout the polymer matrix as nanosized particles and the alkylonium ion is substantially covalently linked to the matrix polymer chains. The present invention further provides a process for the preparation of polymer-phyllosilicate nanocomposite.

  本发明提供了一种聚合物-云母纳米复合材料组合物，其包括（a）10-99.95%重量的基体聚合物和（b）0.05-90%重量的亲水性合成云母和天然云母，这些云母与修饰剂和具有反应性基团的烷基铵离子进行插层。云母在聚合物基体中以纳米级颗粒的形式均匀分散和/或剥离，并且烷基铵离子与基体聚合物链基本上共价连接。本发明还提供了一种制备聚合物-云母纳米复合材料的方法。
• prosthetic devices
  申请人：ALLIED CORPORATION

  公开号：EP0144534A2

  公开（公告）日：1985-06-19

  A sterile shaped prosthetic device, suitable for insertion into a mammalian body, is at least partly composed of a bioresorbable material that is digestible by macrophages, its surface properties favor the attachment and adhesion of fibroblast cells capable of producing collagen for organized connective tissues, and the material itself or its degradation products can induce in vivo the formation of new capillary vessels (termed a "vasotropic" effect herein). Preferred prosthetic devices have through passages, the interspatial dimensions which are sufficient to permit several layers of mammalian cells to form within each passage. The invading fibroblast cells commence formation of collagen leading to connective tissue while macrophages and extracellular enzymes degrade the material, and newly formed capillary vessels penetrate the prosthesis and provide blood containing oxygen and nutrients which further the formation of organized tissue around as well as within the prosthetic device.

  适用于插入哺乳动物体内的无菌形状假体装置至少部分由生物可吸收材料组成，这种材料可被巨噬细胞消化，其表面特性有利于能够产生胶原蛋白的成纤维细胞的附着和粘附，从而形成有组织的结缔组织，而且材料本身或其降解产物可诱导体内新毛细血管的形成（此处称为 "血管扩张 "效应）。首选的假体装置具有通孔，其空间尺寸足以让哺乳动物细胞在每个通孔内形成几层。侵入的成纤维细胞开始形成胶原蛋白，形成结缔组织，同时巨噬细胞和细胞外酶降解这些材料，新形成的毛细血管穿透假体，提供含有氧气和营养物质的血液，进一步在假体装置周围和内部形成有组织的组织。
• Intercalates and exfoliates formed with oligomers and polymers and composite materials containing same
  申请人：AMCOL INTERNATIONAL CORPORATION

  公开号：EP0747451A2

  公开（公告）日：1996-12-11

  Nanocomposites are manufactured by combining a host material, such as an organic solvent or a matrix polymer and exfoliated intercalates formed by contacting a phyllosilicate with a polymer to adsorb or intercalate the polymer between adjacent phyllosilicate platelets. Sufficient polymer is adsorbed between adjacent phyllosilicate platelets to expand the adjacent platelets to a spacing of at least about 5 Å, preferably at least about 10 Å (as measured after water removal), up to about 100 Å and preferably in the range of about 30-40 Å, so that the intercalate easily can be exfoliated, e.g., when mixed with an organic solvent or a polymer melt, to provide a carrier material for drugs and the like, or to provide a matrix polymer/platelet composite (nanocomposite) material - the platelets being exfoliated from the intercalate.

  纳米复合材料的制造方法是将有机溶剂或基质聚合物等主体材料与剥离的插层材料相结合，剥离的插层材料是通过将植硅酸盐与聚合物接触，使聚合物吸附或插层在相邻的植硅酸盐小板之间而形成的。在相邻的纤维硅酸盐小板之间吸附足够的聚合物，使相邻的小板之间的间距扩大到至少约 5 Å，最好至少约 10 Å（脱水后测量），最大约 100 Å，最好在约 30-40 Å 的范围内，这样夹杂物就很容易剥离，例如、当与有机溶剂或聚合物熔体混合时，提供药物等的载体材料，或提供基质聚合物/小板复合（纳米复合）材料--小板从中间产物中剥离。
• Intercalates; exfoliates; process for manufacturing intercalates and exfoliates and composite materials containing same
  申请人：AMCOL INTERNATIONAL CORPORATION

  公开号：EP0747323A1

  公开（公告）日：1996-12-11

  Intercalates formed by mixing the phyllosilicate with a polymer and a liquid carrier, and extruding the mixture through a die-opening to adsorb or intercalate the polymer between adjacent phyllosilicate platelets. Sufficient polymer is adsorbed between adjacent phyllosilicate platelets to expand the adjacent platelets to a spacing of at least about 10 Å (as measured after water removal), up to about 55 Å and preferably in the range of about 30-40 Å, so that the intercalate easily can be exfoliated into individual platelets by heating the polymer to its melting point, to provide a matrix polymer/platelet composite material.

  将植硅酸盐与聚合物和液体载体混合，然后通过模头开口挤出混合物，使聚合物吸附或插层在相邻的植硅酸盐小板之间。 相邻的纤维硅酸盐小板之间吸附足够的聚合物，使相邻小板的间距扩大到至少约 10 Å（脱水后测量），最大约 55 Å，最好在约 30-40 Å 的范围内，这样，通过将聚合物加热到熔点，插层很容易剥离成单个小板，从而提供基质聚合物/小板复合材料。