北美放线菌粘糖 | 4682-46-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 北美放线菌粘糖
• 英文名称: 3-O-methyl-D-galactose
• 英文别名: 3-O-Methyl-D-galaktose；(2R,3S,4S,5R)-2,4,5,6-Tetrahydroxy-3-methoxyhexanal
• CAS: 4682-46-6
• 化学式: C₇H₁₄O₆
• 分子量: 194.185
• InChiKey: RMTFNDVZYPHUEF-JRTVQGFMSA-N

物化性质

• 熔点：
  144-147 °C
• 沸点：
  474.2±45.0 °C(Predicted)
• 密度：
  1.394±0.06 g/cm3(Predicted)
• 稳定性/保质期：
  在常温常压下保持稳定

计算性质

• 辛醇/水分配系数(LogP)：
  -2.9
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  107
• 氢给体数：
  4
• 氢受体数：
  6

安全信息

• 储存条件：
  常温下，应避免阳光直射并存放在通风、干燥的地方，建议密封保存。

反应信息

• 作为反应物：
  描述：

  北美放线菌粘糖 在 吡啶 、 盐酸 作用下， 生成 2,4,5,6-Tetra-O-acetyl-3-O-methyl-D-galactose-diaethyl-dithioacetal
  参考文献：
  名称：

  Williams,D.T.; Jones,J.K.N., Canadian Journal of Chemistry, 1967, vol. 45, p. 741 - 744

  摘要：

  DOI：
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 硫酸 、 丙酮 作用下， 生成 北美放线菌粘糖
  参考文献：
  名称：

  Reber; Reichstein, Helvetica Chimica Acta, 1945, vol. 28, p. 1164,1168

  摘要：

  DOI：

文献信息

• Analysis of mixtures of some mono-O-methylaldoses with the common aldoses by g.l.c.-m.s. after isopropylidenation
  作者：Kai H. Aamlid、Svein Morgenlie

  DOI：10.1016/0008-6215(83)88350-5

  日期：1983.12

  Abstract The O-isopropylidene derivatives of seven naturally occurring mono-O-methylaldoses have been characterised by g.l.c.-m.s. G.l.c. conditions have been found under which almost complete separation of the O-methyl sugars and the common aldoses as their O-isopropylidene derivatives can be achieved. This analysis procedure has been applied to the hydrolysates of three polysaccharides that contain

  摘要已经通过glc-ms Glc条件表征了七个天然存在的单-O-甲基醛糖的O-异亚丙基衍生物，在该条件下，O-甲基糖和普通醛糖几乎可以完全分离，因为它们的O-异亚丙基衍生物可以被分离。实现。该分析程序已应用于含有O-甲基糖的三种多糖的水解产物。
• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。
• Anti-fouling Paints and Coatings
  申请人：Reactive Surfaces LTD

  公开号：US20150191607A1

  公开（公告）日：2015-07-09

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peptide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文披露了聚合材料，例如涂层、塑料、层压材料、复合材料、弹性体、粘合剂或密封剂；表面处理，例如纺织品整理或蜡；填充剂，用于这种聚合材料或表面处理，包括酯酶（例如脂肪水解酶、硫酸酯水解酶、有机磷化合物降解酶）的酶，降解细胞壁和/或细胞膜成分的酶（例如溶菌酶、裂解转葡糖苷酶），生物杀菌或生物稳定肽，和/或肽酶。本文还披露了通过将酶并入能够通过脂肪水解酶、水解酶和/或脲酶的活性进行化学交联的材料中，改变材料性能（例如使用寿命、柔韧性或刚度）的方法。
• Antibiotic A 40926 complex and its pure factors PA, PB, A, B and BO
  申请人：GRUPPO LEPETIT S.p.A.

  公开号：EP0177882A2

  公开（公告）日：1986-04-16

  The present invention concerns a new antibiotic substance arbitrarily denominated antibiotic A 40926 complex and its factors antibiotic A 40926 factor A antibiotic A 40926 factor B. antibiotic A 40926 factor Bo, antibiotic A 40926 factor PA and antibiotic A 40926 factor PB, a process for producing them by culturing the new strain Actinomadura sp. ATCC 39727 or an A 40926 producing variant or mutant thereof and the use of these new antibiotic substances in the treatment of infectious diseases involving microorganisms susceptible to them. The antibiotic substances of the invention are glycopeptidic substances belonging to the vancomycin class or antibiotics which have binding capacity to Acyl-D-Alanyl-D-Alanine.

  本发明涉及一种任意命名为抗生素A 40926复合物及其因子抗生素A 40926因子A抗生素A 40926因子B、抗生素A 40926因子Bo、抗生素A 40926因子PA和抗生素A 40926因子PB的新抗生素物质，一种通过培养新菌株Actinomadura sp. ATCC 39727或其产生A 40926的变种或突变体来生产它们的工艺，以及这些新抗生素物质在治疗涉及对它们易感的微生物的感染性疾病中的用途。 本发明的抗生素物质是属于万古霉素类的糖肽物质或与Acyl-D-丙氨酰-D-丙氨酸有结合能力的抗生素。
• Antibiotic A 40926 N-acylaminoglucuronyl aglycons and antibiotic A 40926 aglycon
  申请人：GRUPPO LEPETIT S.p.A.

  公开号：EP0240609A2

  公开（公告）日：1987-10-14

  The present invention concerns new antibiotic substances denominated antibiotic A 40926 N-acylamino­glucuronyl aglycon complex AB, antibiotic A 40926 N-acylaminoglucuronyl aglycon factor A, antibiotic A 40926 N-acylaminoglucuronyl aglycon factor B, antibiotic A 40926 N-acylaminoglucuronyl aglycon factor B₀, antibiotic A 40926 N-acylaminoglucuronyl aglycon factor B₁, antibiotic A 40926 aglycon and the addition salts thereof, a process for their preparation starting from antibiotic A 40926 complex or a factor thereof, and their use in the treatment of infectious diseases involving microorganisms susceptible to them.

  本发明涉及被命名为抗生素 A 40926 N-acylaminoglucuronyl aglycon complex AB、抗生素 A 40926 N-acylaminoglucuronyl aglycon factor A、抗生素 A 40926 N-acylaminoglucuronyl aglycon factor B、抗生素 A 40926 N-acylaminoglucuronyl aglycon factor B₀、抗生素 A 40926 N-acylaminoglucuronyl aglycon factor B₁、抗生素 A 40926 aglycon 及其加成盐、从抗生素 A 40926 复合物或其因子开始制备它们的工艺，以及它们在治疗涉及对其易感的微生物的传染性疾病中的用途。