1-hydroxybutan-2-yl propionate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1-hydroxybutan-2-yl propionate
• 英文别名: 1-Hydroxybutan-2-yl propanoate
• 化学式: C₇H₁₄O₃
• 分子量: 146.186
• InChiKey: CSBVHANFWPADPK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1,2-环氧丁烷 、 丙酸 在 graphite oxide 作用下， 反应 0.17h， 以83%的产率得到1-hydroxybutan-2-yl propionate
  参考文献：
  名称：

  氧化石墨催化羧酸与环氧的高效和区域选择性开环

  摘要：

  据报道，在无金属条件下，环氧化物与各种羧酸的有效，简单和区域选择性的开环反应。环氧化物的开环发生在作为有效和可用催化剂的氧化石墨存在下，以高收率生产相应的2-羟基单酯和1,2-二酯衍生物。亲核试剂的区域选择性攻击，较短的反应时间，无金属条件和催化剂的可重复使用性是本方案的优点。

  DOI：

  10.2174/1570178616666190401194252

文献信息

• PROCESS FOR FUNCTIONALIZATION OF UNSATURATED COMPOUNDS
  申请人：Casciato Stefano

  公开号：US20130211033A1

  公开（公告）日：2013-08-15

  The present invention relates to a process for synthesizing a multifunctional compound, including the reaction of a compound of formula (II) with atmospheric or molecular oxygen, in the presence of at least one aldehyde of formula (III), and optionally in the presence of at least one catalyst or at least one radical initiator; wherein: R 10 , R 20 , R 30 , R 40 , R 50 , L 2 , R 60 , R 7 , R 8 , and R 9 are as described in the claims. The invention also relates to the use of these compounds as monomers for the preparation of polyurethane. The invention also relates to the use of these compounds as monomers of polymers or of biopolymers.

  本发明涉及一种合成多功能化合物的方法，包括将式（II）的化合物与大气或分子氧在至少一种醛（式（III））的存在下反应，可选地在至少一种催化剂或至少一种自由基引发剂的存在下；其中：R10、R20、R30、R40、R50、L2、R60、R7、R8和R9如权利要求中所述。该发明还涉及将这些化合物用作聚氨酯制备中的单体的用途。该发明还涉及将这些化合物用作聚合物或生物聚合物的单体的用途。
• Process for synthesizing a multicomponent acidic catalyst composition by an organic solution method
  申请人：EXXON RESEARCH AND ENGINEERING COMPANY

  公开号：EP0111998A1

  公开（公告）日：1984-06-27

  A process for preparing a catalyst composition wherein a Metal Hydrocarboxide I, such as aluminum secbutoxide, a Metal Hydrocarboxide Il, such as silicon ethoxide, an acidic phosphorus-oxygen composition, such as phosphoric acid, and water, are reacted in the presence of a liquid organic medium, such as acetone, to form a catalyst precursor composition, which is then calcined to form the catalyst, is disclosed. The catalyst is useful for condensing carboxylic acids or their ester with aldehydes or acetals to synthesize a, β-ethylenically unsaturated acids or esters, such as methylmethacrylate.

  本发明公开了一种制备催化剂组合物的工艺，其中金属烃 I（如仲丁醇铝）、金属烃 Il（如硅乙醇）、酸性磷氧组合物（如磷酸）和水在液体有机介质（如丙酮）存在下反应形成催化剂前体组合物，然后煅烧形成催化剂。 该催化剂可用于羧酸或其酯与醛或乙醛缩合，合成 a、β-乙烯基不饱和酸或酯，如甲基丙烯酸甲酯。
• Process for synthesizing a multicomponent acidic catalyst composition containing zirconium by an organic solution method
  申请人：EXXON RESEARCH AND ENGINEERING COMPANY

  公开号：EP0126194A1

  公开（公告）日：1984-11-28

  A process for preparing a catalyst composition wherein a Metal Hydrocarboxide I, such as aluminum secbutoxide, a Metal Hydrocarboxide II, such as zirconium butoxide, an acidic phosphorus-oxygen composition, such as phosphoric acid, and water, are reacted in the presence of a liquid organic medium, such as acetone, to form a catalyst precursor composition, which is then calcined to form the catalyst, is disclosed. The catalyst is useful for condensing carboxylic acids or their ester with aldehydes or acetals to synthesize α,β-ethylenically unsaturated acids or esters, such as methylmethacrylate.

  本发明公开了一种制备催化剂组合物的工艺，其中金属碳氢化合物 I（如仲丁醇铝）、金属碳氢化合物 II（如丁氧化锆）、酸性磷氧组合物（如磷酸）和水在液体有机介质（如丙酮）存在下反应形成催化剂前体组合物，然后煅烧形成催化剂。该催化剂可用于将羧酸或其酯与醛或乙醛缩合，合成α，β-乙烯基不饱和酸或酯，如甲基丙烯酸甲酯。
• Process for the production of alpha, beta-ethylenically unsaturated esters
  申请人：EXXON RESEARCH AND ENGINEERING COMPANY

  公开号：EP0147156A2

  公开（公告）日：1985-07-03

  A process for producing alpha, beta-ethylenically unsaturated acids and esters thereof, such as methacrylic acid and methyl methacrylate using a by-product ether (such as dimethyl ether) recycle step is disclosed.

  本发明公开了一种利用副产品醚（如二甲醚）循环步骤生产α、β-乙烯基不饱和酸及其酯类（如甲基丙烯酸和甲基丙烯酸甲酯）的工艺。
• US4444904A
  申请人：——

  公开号：US4444904A

  公开（公告）日：1984-04-24