1,4-diphenethyltetrasulfane

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,4-diphenethyltetrasulfane
• 英文别名: 2-(2-Phenylethyltetrasulfanyl)ethylbenzene
• 化学式: C₁₆H₁₈S₄
• 分子量: 338.583
• InChiKey: KCRWMYZSRAKJTM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  20
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  101
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  3-Phenyl-propionic acid 2-thioxo-2H-pyridin-1-yl ester 在 1,2,3,4,5,6,7,8-八硫杂环辛烷 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 生成 2-(苯基乙硫基)-吡啶 、 2,2'-二硫二吡啶 、 、 1,4-diphenethyltetrasulfane
  参考文献：
  名称：

  碳自由基与硫的反应。从羧酸方便地合成硫醇

  摘要：

  展示了利用碳自由基和元素硫以高收率合成硫醇的新方法。该程序适用于1°，2°和3°羧酸。

  DOI：

  10.1016/0040-4039(94)88074-3

文献信息

• COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING HYPOXIC OR ISCHEMIC INJURY
  申请人：Wintner Edward A.

  公开号：US20100130555A1

  公开（公告）日：2010-05-27

  A method for treating or preventing injury of a biological material exposed to hypoxic or ischemic conditions comprising contacting the biological material with an effective amount of a compound is disclosed. The compound has the following structure (I): R 1 —(S) n —R 2 (I) or a stereoisomer, pharmaceutically acceptable salt or prodrug thereof, wherein R 1 , R 2 , and n are as defined herein. Compounds, methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
• US8202997B2
  申请人：——

  公开号：US8202997B2

  公开（公告）日：2012-06-19
• [EN] COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING HYPOXIC OR ISCHEMIC INJURY<br/>[FR] COMPOSITIONS ET PROCÉDÉS POUR TRAITER OU PRÉVENIR UNE LÉSION HYPOXIQUE OU ISCHÉMIQUE
  申请人：IKARIA INC

  公开号：WO2010045582A2

  公开（公告）日：2010-04-22

  A method for treating or preventing injury of a biological material exposed to hypoxic or ischemic conditions comprising contacting the biological material with an effective amount of a compound is disclosed. The compound has the following structure (I): R1_(S)n-R2 or a stereoisomer, pharmaceutically acceptable salt or prodrug thereof, wherein R1, R2, and n are as defined herein. Compounds, methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
• The reaction of carbon radicals with sulfur. A convenient synthesis of thiols from carboxylic acids
  作者：Derek H.R. Barton、Enzo Castagnino、Joseph Cs. Jaszberenyi

  DOI：10.1016/0040-4039(94)88074-3

  日期：1994.8

  A new synthesis of thiols in high yield utilizing carbon radicals and elemental sulfur is demonstrated. The procedure is applicable to 1°, 2° and 3° carboxylic acids.

  展示了利用碳自由基和元素硫以高收率合成硫醇的新方法。该程序适用于1°，2°和3°羧酸。