1-bromo-4-(oct-7-enyloxy)benzene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-bromo-4-(oct-7-enyloxy)benzene
• 化学式: C₁₄H₁₉BrO
• 分子量: 283.208
• InChiKey: JIQKARPGFIKWEH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.96
• 重原子数：
  16.0
• 可旋转键数：
  8.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  9.23
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  1-bromo-4-(oct-7-enyloxy)benzene 在 magnesium 、 1,2-二溴乙烷 、 三氯化磷 作用下， 以 四氢呋喃 为溶剂， 以92 %的产率得到tris-(4-oct-7-enyloxy-phenyl)-phosphane
  参考文献：
  名称：

  Square-Planar and Octahedral Gyroscope-Like Metal Complexes Consisting of Dipolar Rotators Encased in Dibridgehead Di(triaryl)phosphine Stators: Syntheses, Structures, Dynamic Properties, and Reactivity

  摘要：

  For a variety of purposes, it is of interest to embed metals in cagelike trans-spanning di(triaryl)phosphine ligands. Toward this end, a combination of P(p-C6H4O(CH2)mCH═CH2)3 [3; m = 4 (a), 5 (b), 6 (c), and 7 (d)], [Rh(COD)(μ-Cl)]2, and CO gives square-planar trans-Rh(CO)(Cl)[P(p-C6H4O(CH2)mCH═CH2)3]2 (4a–4d). Reactions of 4b–4d with Grubbs’ catalyst (first generation) and then H2 (catalyst PtO2)

  DOI：

  10.1021/acs.inorgchem.2c02855
• 作为产物：
  描述：

  4-溴苯酚 、 8-溴-1-辛烯 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以94 %的产率得到1-bromo-4-(oct-7-enyloxy)benzene
  参考文献：
  名称：

  Square-Planar and Octahedral Gyroscope-Like Metal Complexes Consisting of Dipolar Rotators Encased in Dibridgehead Di(triaryl)phosphine Stators: Syntheses, Structures, Dynamic Properties, and Reactivity

  摘要：

  For a variety of purposes, it is of interest to embed metals in cagelike trans-spanning di(triaryl)phosphine ligands. Toward this end, a combination of P(p-C6H4O(CH2)mCH═CH2)3 [3; m = 4 (a), 5 (b), 6 (c), and 7 (d)], [Rh(COD)(μ-Cl)]2, and CO gives square-planar trans-Rh(CO)(Cl)[P(p-C6H4O(CH2)mCH═CH2)3]2 (4a–4d). Reactions of 4b–4d with Grubbs’ catalyst (first generation) and then H2 (catalyst PtO2)

  DOI：

  10.1021/acs.inorgchem.2c02855

文献信息

• Concave 1,10-Phenanthrolines as Ligands for Cyclopropanations - Towards a Deeper Understanding of the Stereoselectivity
  作者：Friederike Eggers、Ulrich Lüning

  DOI：10.1002/ejoc.200801261

  日期：2009.5

  Four new mono- and bimacrocyclic 1,10-phenanthrolines – 3b and 4a–c – containing aryl bridgeheads have been synthesised. The etherification of the aryl bridgeheads was accomplished by Williamson or Mitsunobu reactions. A key step in the synthesis of the macrocyclic phenanthrolines 3 and 4 is the Suzuki coupling of 2,9-diiodo-1,10-phenanthroline (12) with the appropriately substituted boronic acids

  已经合成了四种新的单和双大环 1,10-菲咯啉 - 3b 和 4a-c - 含有芳基桥头。芳基桥头的醚化是通过威廉姆森或光信反应完成的。合成大环菲咯啉 3 和 4 的关键步骤是 2,9-二碘-1,10-菲咯啉 (12) 与适当取代的硼酸 17 和 20 的 Suzuki 偶联。闭环复分解和氢化完成了合成。得到的大环 1,10-菲咯啉 3b 和 4a-c 作为配体在铜（I）催化的立体选择性环丙烷化反应中进行了测试。（© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009）
• “Giant” Gyroscope-Like Molecules Consisting of Dipolar Cl-Rh-CO Rotators Encased in Three-Spoke Stators That Define 25–27-Membered Macrocycles
  作者：Leyong Wang、Frank Hampel、John A. Gladysz

  DOI：10.1002/anie.200601191

  日期：2006.6.26
• Square-Planar and Octahedral Gyroscope-Like Metal Complexes Consisting of Dipolar Rotators Encased in Dibridgehead Di(triaryl)phosphine Stators: Syntheses, Structures, Dynamic Properties, and Reactivity
  作者：Alexander L. Estrada、Leyong Wang、Gisela Hess、Frank Hampel、John A. Gladysz

  DOI：10.1021/acs.inorgchem.2c02855

  日期：2022.10.31

  For a variety of purposes, it is of interest to embed metals in cagelike trans-spanning di(triaryl)phosphine ligands. Toward this end, a combination of P(p-C6H4O(CH2)mCH═CH2)3 [3; m = 4 (a), 5 (b), 6 (c), and 7 (d)], [Rh(COD)(μ-Cl)]2, and CO gives square-planar trans-Rh(CO)(Cl)[P(p-C6H4O(CH2)mCH═CH2)3]2 (4a–4d). Reactions of 4b–4d with Grubbs’ catalyst (first generation) and then H2 (catalyst PtO2)