2-(4-methoxyphenyl)-2H-benzo[h]chromene

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 2-(4-methoxyphenyl)-2H-benzo[h]chromene
• 化学式: C₂₀H₁₆O₂
• 分子量: 288.346
• InChiKey: WGNBYZOHKPCRDU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  萘酚 、 4-甲氧基肉桂醛 在 邻苯二胺 作用下， 以 二氯甲烷 为溶剂， 反应 17.0h， 以84%的产率得到2-(4-methoxyphenyl)-2H-benzo[h]chromene
  参考文献：
  名称：

  通过芳胺催化曼尼希环化级联反应轻松合成 2H-苯并[h]色烯

  摘要：

  开发了一种简单的芳胺催化曼尼希环化级联反应，用于轻松合成取代的 2 H-苯并[ h ]色烯。该过程的显着特点包括在简单的苯胺催化下有效生成邻醌甲基化物（ o -QM）。温和的反应条件允许广谱的1-和2-萘酚以及反式肉桂醛高效地参与级联序列。

  DOI：

  10.3390/molecules26123617

文献信息

• POLARIZING PHOTOCHROMIC ARTICLES
  申请人：Transitions Optical, Inc.

  公开号：EP2718754A1

  公开（公告）日：2014-04-16
• [EN] POLARIZING PHOTOCHROMIC ARTICLES<br/>[FR] ARTICLES PHOTOCHROMIQUES POLARISANTS
  申请人：TRANSITIONS OPTICAL INC

  公开号：WO2012170066A1

  公开（公告）日：2012-12-13

  Photochromic articles that include a substrate, a primer layer that includes a first photochromic compound, and a photochromic - dichroic layer over the primer layer that includes a photochromic - dichroic compound. The first photochromic compound and the photochromic - dichroic compound each are selected such that the photochromic - dichroic compound has an unactivated state terminal minimum absorbance wavelength that is less than or equal to the unactivated state terminal minimum absorbance of the underlying first photochromic compound. The photochromic articles further include a topcoat layer over the photochromic - dichroic layer. The topcoat layer can include a second photochromic compound that has an unactivated state terminal minimum absorbance wavelength that is less than the unactivated state terminal minimum absorbance wavelength of the underlying photochromic - dichroic compound. The photochromic articles provide, for example, a combination of linear polarizing properties, and reduced percent transmittance of ultraviolet light and/or visible light when in an activated state, such as when exposed to sufficient actinic light.
• Facile Synthesis of 2H-Benzo[h]Chromenes via an Arylamine-Catalyzed Mannich Cyclization Cascade Reaction
  作者：Yueteng Zhang、Peng Ji、Xiang Meng、Feng Gao、Fanxun Zeng、Wei Wang

  DOI：10.3390/molecules26123617

  日期：——

  Mannich-cyclization cascade reaction was developed for facile synthesis of substituted 2H-benzo[h]chromenes. The notable feature of the process included the efficient generation of ortho-quinone methides (o-QMs) catalyzed by a simple aniline. The mild reaction conditions allowed for a broad spectrum of 1- and 2-naphthols and trans-cinnamaldehydes to engage in the cascade sequence with high efficiency.

  开发了一种简单的芳胺催化曼尼希环化级联反应，用于轻松合成取代的 2 H-苯并[ h ]色烯。该过程的显着特点包括在简单的苯胺催化下有效生成邻醌甲基化物（ o -QM）。温和的反应条件允许广谱的1-和2-萘酚以及反式肉桂醛高效地参与级联序列。