双(2,2,2-三氯乙基)己二酸酯 | 57392-52-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 双(2,2,2-三氯乙基)己二酸酯
• 英文名称: bis(2,2,2-trichloroethyl) adipate
• 英文别名: di-(2,2,2-trichloroethyl)adipate；Bis(2,2,2-trichloroethyl) hexanedioate
• CAS: 57392-52-6
• 化学式: C₁₀H₁₂Cl₆O₄
• 分子量: 408.921
• InChiKey: ORLGXGVFGFWARG-UHFFFAOYSA-N

物化性质

• 沸点：
  491.5±40.0 °C(Predicted)
• 密度：
  1.520±0.06 g/cm3(Predicted)
• 保留指数：
  2858

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  20
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  双(2,2,2-三氯乙基)己二酸酯 、 butyl-α-D-glucopyranoside 在 lipase of Mucor miehei Lypozime<*> 作用下， 以 neat (no solvent) 为溶剂， 反应 48.0h， 以52%的产率得到butyl 6-O-(adipyl)-α-D-glucopyranoside
  参考文献：
  名称：

  多功能酶促二酸酯合成丁基α-D-吡喃葡萄糖苷

  摘要：

  用猪胰脂肪酶在丙酮中研究了二酸对α-D-吡喃葡萄糖苷丁基的酶促酯化反应。酰化剂的性质影响反应的区域特异性。开发了一种化学酶促反应方案，以固定化的Mucor miehei脂肪酶（Lipozyme®）在无溶剂的过程中，使用活化的二酸作为酰基供体，获得了二酸酯。

  DOI：

  10.1016/s0040-4020(01)80240-4
• 作为产物：
  描述：

  2,2,2-三氯乙醇 、 己二酰氯 在 POLYDMAP 作用下， 反应 24.0h， 以86%的产率得到双(2,2,2-三氯乙基)己二酸酯
  参考文献：
  名称：

  Rational Control of Polymer Molecular Weight and Dispersity during Enzyme-Catalyzed Polyester Synthesis in Supercritical Fluids

  摘要：

  Enzyme-catalyzed polyester synthesis has been investigated with special emphasis on modulation of polymer molecular weight and dispersity. Supercritical fluids were also used for isolating low-disperity polyester fractions by changing pressure. Enzymatic synthesis of low-dispersity polyesters was achieved in supercritical fluoroform. The synthesized polymer molecular weight can be controlled by changing the pressure.

  DOI：

  10.1021/ja00118a009

文献信息

• Process for the production of polyesters using enzymes and supercritical fluids
  申请人：Bayer Corporation

  公开号：EP0729993A1

  公开（公告）日：1996-09-04

  A process of preparing a polyester by reacting a diol with an acid or acid ester in the presence of a solid enzyme and in a supercritical fluid is described.

  描述了一种在固体酶存在下和超临界流体中通过二元醇与酸或酸酯反应制备聚酯的工艺。
• POLYESTER BASED DEGRADABLE MATERIALS AND IMPLANTABLE BIOMEDICAL ARTICLES FORMED THEREFROM
  申请人：Ashby Valerie

  公开号：US20090221781A1

  公开（公告）日：2009-09-03

  A method of making an aliphatic polyester prepolymer, comprising: reacting, alone or in combination with other reactants, a diol with at least a first diacid (or a diester of said first diacid) to produce an aliphatic polyester prepolymer. The first diacid is preferably a trans-beta-hydromuconic acid (HMA). In some embodiments, the diol contains at least one ether linkage. In some embodiments the diol is further reacted with at a second diacid, or a diester of said second diacid, wherein said second diacid is different from said first diacid. Prepolymers produced from such processes and articles formed therefrom are also described.
• Polyester Based Degradable Materials and Implantable Biomedical Articles Formed Therefrom
  申请人：Ashby Valerie

  公开号：US20120027719A1

  公开（公告）日：2012-02-02

  A method of making an aliphatic polyester prepolymer, comprising: reacting, alone or in combination with other reactants, a diol with at least a first diacid (or a diester of said first diacid) to produce an aliphatic polyester prepolymer. The first diacid is preferably a trans-beta-hydromuconic acid (HMA). In some embodiments, the diol contains at least one ether linkage. In some embodiments the diol is further reacted with at a second diacid, or a diester of said second diacid, wherein said second diacid is different from said first diacid. Prepolymers produced from such processes and articles formed therefrom are also described.
• USE OF LONG CHAIN AMINES AND DIFUNCTIONAL COMPOUNDS AS TRACERS
  申请人：Baker Hughes Incorporated

  公开号：US20150377010A1

  公开（公告）日：2015-12-31

  Non-halogenated molecules including, but are not necessarily limited, to alkyl and aromatic amines having from 8 to 18 carbon atoms and salts of these amines, diols having the formula HO—(CH 2 ) n —OH, diamines having the formula H 2 N—(CH 2 ) n —NH 2 , dicarboxylic acids having the formula HO.CO—(CH 2 ) n —CO.OH, diesters having the formula R′O.CO—(CH 2 ) n —CO.OR″, where n is 4 to 18, and R′ and R″ are independently straight or branched alkyl or aromatic groups of 1-20 carbon atoms, and combinations thereof are used as tracers to measure oil and/or water fluid returns, e.g. from a hydraulic fracturing job. The non-halogenated molecules may be combined with substrates and introduced into a subterranean location, desorbed and recovered from the subterranean location with a fluid, reacted with a reagent to give a derivatized tracer. The presence of the derivatized tracer is then detected in the recovered fluid. Different non-halogenated tracers may be used for each hydraulic fracturing stage.
• US5147791A
  申请人：——

  公开号：US5147791A

  公开（公告）日：1992-09-15