双(2-乙氧基乙基)己二酸酯 | 109-44-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 双(2-乙氧基乙基)己二酸酯
• 中文别名: 雙乙氧乙基己二酸酯；双(2-乙氧乙基)己二酸酯
• 英文名称: adipic acid bis-(2-ethoxy-ethyl ester)
• 英文别名: Adipinsaeure-bis-(2-aethoxy-aethylester)；hexanedioic acid, bis(2-ethoxyethyl) ester；bis(2-ethoxyethyl) adipate；bis-2-ethoxyethyl adipate；bis(2-ethoxyethyl) hexanedioate
• CAS: 109-44-4
• 化学式: C₁₄H₂₆O₆
• 分子量: 290.357
• InChiKey: NJEMMCIKSMMBDM-UHFFFAOYSA-N

物化性质

• 沸点：
  164-166 °C4 mm Hg(lit.)
• 密度：
  1.038 g/mL at 25 °C(lit.)
• 闪点：
  >230 °F
• 溶解度：
  0.01 M
• 保留指数：
  1880;1880;1924

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  20
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.857
• 拓扑面积：
  71.1
• 氢给体数：
  0
• 氢受体数：
  6

安全信息

• TSCA：
  T
• 危险品标志：
  Xi
• 安全说明：
  S26,S36
• 危险类别码：
  R36/37/38
• WGK Germany：
  3
• RTECS号：
  AU9300000
• 海关编码：
  2918990090
• 储存条件：
  库房应保持通风、低温和干燥的环境。

SDS

Name:	Bis(2-ethoxyethyl) adipate 97% (GC) Material Safety Data Sheet
Synonym:	Bis(2-ethoxyethyl)hexanedioate; Adipic acid, bis(2-ethoxyethyl) ester; Diethoxy ethyl adipate; Hexanedioic acid, bis(2-ethoxyethyl) ester; Hexanoic acid, bis(2-ethoxyethyl) este
CAS:	109-44-4

Section 1 - Chemical Product MSDS Name:Bis(2-ethoxyethyl) adipate 97% (GC) Material Safety Data Sheet
Synonym:Bis(2-ethoxyethyl)hexanedioate; Adipic acid, bis(2-ethoxyethyl) ester; Diethoxy ethyl adipate; Hexanedioic acid, bis(2-ethoxyethyl) ester; Hexanoic acid, bis(2-ethoxyethyl) este

---

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
109-44-4	Bis(2-ethoxyethyl) adipate	99	203-673-0

Hazard Symbols: XI
Risk Phrases: 36

---

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis.
Skin:
May cause severe skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation:
Causes respiratory tract irritation. Can produce delayed pulmonary edema.
Chronic:
Effects may be delayed.

---

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

---

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.

---

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Provide ventilation.

---

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Use with adequate ventilation. Wash clothing before reuse.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

---

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 109-44-4: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

---

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Clear liquid
Color: clear, colorless
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 166 deg C @ 4.00mm Hg
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: 144 deg C ( 291.20 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Not available.
Specific Gravity/Density: Not available.
Molecular Formula: C14H26O6
Molecular Weight: 290.35

---

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, excess heat, strong oxidants.
Incompatibilities with Other Materials:
No information found..
Hazardous Decomposition Products:
Acrid smoke and fumes.
Hazardous Polymerization: Has not been reported.

---

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 109-44-4: AU9300000 LD50/LC50:
CAS# 109-44-4: Draize test, rabbit, skin: 100 mg/24H Severe.
Carcinogenicity:
Bis(2-ethoxyethyl) adipate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

---

Section 12 - ECOLOGICAL INFORMATION

---

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

---

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

---

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36 Irritating to eyes.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 39 Wear eye/face protection.
WGK (Water Danger/Protection)
CAS# 109-44-4: No information available.
Canada
CAS# 109-44-4 is listed on Canada's DSL List.
CAS# 109-44-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 109-44-4 is listed on the TSCA inventory.

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

类别：有毒物品

刺激数据

• 皮肤（兔子）：100 毫克/24 小时，重度刺激
• 皮肤（人）：50 毫克/24 小时，轻度刺激

可燃性危险特性

• 可燃
• 受热分解产生刺激性烟雾

储运特性

• 库房应保持通风、低温和干燥

灭火剂

• 干粉、泡沫、砂土、二氧化碳或雾状水

反应信息

• 作为产物：
  描述：

  乙二醇乙醚 、 己二酸 在 硫酸 、 甲苯 作用下， 生成 双(2-乙氧基乙基)己二酸酯
  参考文献：
  名称：

  Ester of polycarboxylic acids

  摘要：

  公开号：

  US01991391A1

文献信息

• ANIMAL ECTOPARASITE CONTROL COMPOSITION
  申请人：NISHIGUCHI Naonobu

  公开号：US20110160251A1

  公开（公告）日：2011-06-30

  The present invention provides an animal ectoparasite control composition containing an insecticidal component and an adipate, and a method of controlling an animal ectoparasite which comprises administering an effective amount of the animal ectoparasite control composition to an animal.

  本发明提供了一种含有杀虫成分和己二酸酯的动物外寄生虫控制组合物，以及一种控制动物外寄生虫的方法，包括向动物施用有效量的动物外寄生虫控制组合物。
• [EN] HEMIACETYL PROFLAVORS<br/>[FR] INGRÉDIENTS FAVORISANT LE GOÛT DE TYPE HÉMIACÉTYLE
  申请人：FIRMENICH & CIE

  公开号：WO2016102424A1

  公开（公告）日：2016-06-30

  Provided herein is a compound having the formula I (I), wherein R1 and R2 are independently selected from a branched or straight C1-C6 alkyl and a C1-C6 alkenyl, n is 1, 2, 3, 4, 5 or 6 and x is independently 0, 1 or 2; provided that when n is 1, x is 2. Also provided herein is a method of releasing acetaldehyde into an aqueous solution comprising delivering a compound of formula I to the aqueious solution wherein R1 and R2 are independently selected from a branched or straight C1-C6 alkyl and a C1-C6 alkenyl, n is 1, 2, 3, 4, 5 or 6 and x is independently 0, 1 or 2; provided that when n is 1, x is 2. Also provided is a flavor or aroma-modifying composition 1 comprising: i) a flavor or aroma-conferring or modifying ingredient, at least one compound according to formula (I) above; ii) at least one ingredient selected from the group consisting of a flavor carrier and a flavor base; and iii) optionally at least one flavor adjuvant.

  本文提供了一种具有化学式I（I）的化合物，其中R1和R2分别选自支链或直链的C1-C6烷基和C1-C6烯基，n为1、2、3、4、5或6，x独立地为0、1或2；但当n为1时，x为2。本文还提供了一种释放乙醛到水溶液中的方法，包括向水溶液中投放具有化学式I的化合物，其中R1和R2分别选自支链或直链的C1-C6烷基和C1-C6烯基，n为1、2、3、4、5或6，x独立地为0、1或2；但当n为1时，x为2。此外，还提供了一种口味或香气调节组合物1，包括：i）一种口味或香气赋予或调节成分，至少一种符合上述化学式（I）的化合物；ii）至少一种选自口味载体和口味基的成分；以及iii）可选择地至少一种口味助剂。
• PRO-FLUORESCENT PROBES
  申请人：Chang Christopher J.

  公开号：US20110130306A1

  公开（公告）日：2011-06-02

  The present invention provides a novel class of pro-fluorescent probes for reactive oxygen species (ROS). One exemplary probe is mitochondria peroxy yellow 1 (MitoPY1), a new type of flurophore for imaging mitochondrial H 2 O 2 in living cells with ROS and spatial specificity. The invention also provides methods of using pro-fluorescent probes to detect analytes. One exemplary method comprises using a pro-fluorescent probe of the invention to detect an explosive.

  本发明提供了一种新型的反应性氧化物（ROS）前荧光探针，其中一种示例探针为线粒体过氧黄1（MitoPY1），一种新型荧光物质，用于在ROS和空间特异性下成像细胞内线粒体H2O2。本发明还提供了使用前荧光探针检测分析物的方法。其中一种示例方法包括使用本发明的前荧光探针检测爆炸物。
• Antistatic plasticisers
  申请人：BP Chemicals Limited

  公开号：EP0252690A2

  公开（公告）日：1988-01-13

  This invention relates to antistatic plastic plasticisers for flexible polar polymers e.g. PVC comprising an alkoxyalkanol ester and a surfactant. The feature of the invention is that the specific combination now claimed shows a synergistic effect in its antistatic plasticising activity. The combination also reduces significantly the surface resistivity of such polymers.

  本发明涉及用于柔性极性聚合物（如聚氯乙烯）的抗静电塑料增塑剂，该增塑剂由一种烷氧基烷醇酯和一种表面活性剂组成。 本发明的特点是，本发明所要求的特定组合在其抗静电增塑活性方面显示出协同效应。 该组合还可显著降低此类聚合物的表面电阻率。
• Stabilization and foaming of polyvinylchloride resins
  申请人：WITCO CORPORATION

  公开号：EP0461745A1

  公开（公告）日：1991-12-18

  An improvement in the method for the foaming of polyvinylchloride resins by the use of a blowing agent and an activator therefor which uses as the activator a mixture of at least one organotin mercapto acid ester and a diorganotin oxide complex with an ester of an oxygen-containing acid.

  使用发泡剂和活化剂使聚氯乙烯树脂发泡的方法的改进，该方法使用至少一种有机锡巯基酸酯和二甘醇锡氧化物络合物与含氧酸酯的混合物作为活化剂。

表征谱图