5-amino-2,4-di-(4-methoxyphenyl)-7-(pyrrolidin-1-yl)-1,6-naphthyridine-8-carbonitrile

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 5-amino-2,4-di-(4-methoxyphenyl)-7-(pyrrolidin-1-yl)-1,6-naphthyridine-8-carbonitrile
• 英文别名: 5-Amino-2,4-bis(4-methoxyphenyl)-7-pyrrolidin-1-yl-1,6-naphthyridine-8-carbonitrile；5-amino-2,4-bis(4-methoxyphenyl)-7-pyrrolidin-1-yl-1,6-naphthyridine-8-carbonitrile
• 化学式: C₂₇H₂₅N₅O₂
• 分子量: 451.528
• InChiKey: FPZYIUGKNOFIBP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  34
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  97.3
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  四氢吡咯 、 4,4’-二甲氧基查耳酮 、 丙二腈 以 乙醇 为溶剂， 以47%的产率得到5-amino-2,4-di-(4-methoxyphenyl)-7-(pyrrolidin-1-yl)-1,6-naphthyridine-8-carbonitrile
  参考文献：
  名称：

  Spectral and photophysical properties of 1,6-naphthyridine derivatives: a new class of compounds for nonlinear optics

  摘要：

  1,6-Naphthyridines are a class of compounds that exhibit second harmonic generation on excitation with a Nd-YAG laser (1064 nm). Solvatochromism has been used to estimate enhancement in the dipole moments on excitation and the values of first-order hyperpolarizability, beta. Photophysical studies on the title compounds show that they have a fluorescence lifetime of about 10 ns and fluorescence quantum yield of similar to 0.05-0.1 in different solvents. Kurtz powder method has been used to find the NLO efficiency of the compounds with reference to urea. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s1386-1425(01)00616-3

文献信息

• Spectral and photophysical properties of 1,6-naphthyridine derivatives: a new class of compounds for nonlinear optics
  作者：V.K Indirapriyadharshini、P Ramamurthy、V Raghukumar、V.T Ramakrishnan

  DOI：10.1016/s1386-1425(01)00616-3

  日期：2002.6

  1,6-Naphthyridines are a class of compounds that exhibit second harmonic generation on excitation with a Nd-YAG laser (1064 nm). Solvatochromism has been used to estimate enhancement in the dipole moments on excitation and the values of first-order hyperpolarizability, beta. Photophysical studies on the title compounds show that they have a fluorescence lifetime of about 10 ns and fluorescence quantum yield of similar to 0.05-0.1 in different solvents. Kurtz powder method has been used to find the NLO efficiency of the compounds with reference to urea. (C) 2002 Elsevier Science B.V. All rights reserved.