双(三苯基膦)硝酸铜(I) | 106678-35-7

• 物质功能分类: 化学试剂 - 有机试剂 - 多环化合物
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 双(三苯基膦)硝酸铜(I)
• 中文别名: 硝酸双（三苯膦）铜（I）；(1,1-菲啰啉)双(三苯基磷)硝酸铜 二氯甲烷络合物
• 英文名称: bis(triphenylphosphino)copper(I) nitrate
• 英文别名: [Cu(PPh3)2]NO3；Bis(triphenylphosphine)copper(I) nitrate；copper(1+);triphenylphosphane;nitrate
• CAS: 106678-35-7
• 化学式: C₃₆H₃₀CuP₂*NO₃
• 分子量: 650.133
• InChiKey: QJNAQZVCFXFYBQ-UHFFFAOYSA-N

物化性质

• 稳定性/保质期：

  遵照规定使用和储存，则不会发生分解。

计算性质

• 辛醇/水分配系数(LogP)：
  6.65
• 重原子数：
  43
• 可旋转键数：
  6
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  62.9
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 储存条件：
  存于阴凉干燥处。

SDS

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Section 1: Product Identification
Chemical Name: Bis(triphenylphosphine)copper (I) nitrate, 99%
CAS Registry Number: 106678-35-7
Formula: [(C6H5)3P]2CuNO3
EINECS Number: none
Chemical Family: metal phosphine complex
Synonym: Cuprous nitrate, Bis(triphenylphosphine) complex

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Section 2: Composition and Information on Ingredients
Ingredient CAS Number Percent ACGIH (TWA) OSHA (PEL)
Title compound 106678-35-7 100% 1mg/m3 (as Cu) 1mg/m3 (as Cu)

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Section 3: Hazards Identification
Emergency Overview: Irritating to skin, eyes and respiratory tract.
Primary Routes of Exposure: Ingestion, inhalation, skin, eyes
Eye Contact: Causes irritation of the eyes.
Skin Contact: Causes slight to mild irritation of the skin.
Inhalation: Dust is irritating to the nose, mucous membranes and respiratory tract.
Ingestion: No information available on the physiological effects of ingestion.
Acute Health Affects: Irritating to skin, eyes and respiratory tract.
Chronic Health Affects: No information on long-term chronic effects.
NTP: No
IARC: No
OSHA: No

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SECTION 4: First Aid Measures
Immediately flush the eyes with copious amounts of water for at least 10-15 minutes. A victim may need
Eye Exposure:
assistance in keeping their eye lids open. Get immediate medical attention.
Wash the affected area with water. Remove contaminated clothes if necessary. Seek medical assistance if
Skin Exposure:
irritation persists.
Remove the victim to fresh air. Closely monitor the victim for signs of respiratory problems, such as difficulty
Inhalation:
in breathing, coughing, wheezing, or pain. In such cases seek immediate medical assistance.
Seek medical attention immediately. Keep the victim calm. Give the victim water (only if conscious). Induce
Ingestion:
vomiting only if directed by medical personnel.

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SECTION 5: Fire Fighting Measures
Flash Point: none
Autoignition Temperature: none
Explosion Limits: none
Extinguishing Medium: carbon dioxide, dry powder or foam
If involved in a fire, fire fighters should be equipped with a NIOSH approved positive pressure self-contained
Special Fire Fighting Procedures:
breathing apparatus and full protective clothing.
Hazardous Combustion and If involved in a fire, this material may emit toxic organic fumes and vapors of phosphorous pentoxide.
Decomposion Products:
Unusual Fire or Explosion Hazards: Contact with combustible material may cause fire.

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SECTION 6: Accidental Release Measures
Spill and Leak Procedures: Small spills can be mixed with vermiculite or sodium carbonate and swept up.

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SECTION 7: Handling and Storage
Handling and Storage: Store in a tightly sealed container. Keep in a cool, dry, well ventilated place.

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SECTION 8: Exposure Controls and Personal Protection
Eye Protection: Always wear approved safety glasses when handling a chemical substance in the laboratory.
Skin Protection: Wear protective clothing and gloves.
Ventilation: Handle the material in an efficient fume hood.
If ventilation is not available a respirator should be worn. The use of respirators requires a Respirator
Respirator:
Protection Program to be in compliance with 29 CFR 1910.134.
Ventilation: Handle the material in an efficient fume hood.
Additional Protection: No additional protection required.

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SECTION 9: Physical and Chemical Properties
Color and Form: white powder
Molecular Weight: 650.12
Melting Point: no data
Boiling Point: no data
Vapor Pressure: no data
Specific Gravity: no data
Odor: not determined
Solubility in Water: insoluble

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SECTION 10: Stability and Reactivity
Stability: air and moisture stable
Hazardous Polymerization: no hazardous polymerization
contact with strong reducing agents or organic matter. Some nitrates can explode if heated to high
Conditions to Avoid:
temperatures.
Incompatibility: reducing agents, organic matter, sulfur
Decomposition Products: carbon monoxide, carbon dioxide, organic fumes, copper oxide, nitrogen oxide and phosphorous oxides.

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SECTION 11: Toxicological Information
RTECS Data: No information available in the RTECS files.
Carcinogenic Effects: No data
Mutagenic Effects: No data
Tetratogenic Effects: No data

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SECTION 12: Ecological Information
Ecological Information: No information available

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SECTION 13: Disposal Considerations
Disposal: Dispose of according to local, state and federal regulations.

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SECTION 14: Transportation
Shipping Name (CFR): Oxidizing solid, N.O.S.
Hazard Class (CFR): 5.1
Additional Hazard Class (CFR): NA
Packaging Group (CFR): III
UN ID Number (CFR): UN# 1479
Shipping Name (IATA): Oxidizing solid, N.O.S.
Hazard Class (IATA): 5.1
Additional Hazard Class (IATA): NA
Packaging Group (IATA): III
UN ID Number (IATA): UN# 1479

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SECTION 15: Regulatory Information
TSCA: Not listed in the TSCA inventory
SARA (Title 313): See Category codes N100 and N151 for reporting.
Second Ingredient: none

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  双(三苯基膦)硝酸铜(I) 、 potassium N-benzyl-N-(4-pyridylmethyl)dithiocarbamate 以 甲醇 、 二氯甲烷 为溶剂， 以87%的产率得到[Cu(PPh3)2(N-benzyl-N-(4-pyridylmethyl)dithiocarbamate)]
  参考文献：
  名称：

  杂配铜(I)黄药/二硫代氨基甲酸酯PPh3配合物的协同金属配体诱导特性

  摘要：

  四种新的杂配单核配合物，[Cu(PPh3)2L1](1) {L1 = (C9H11O2CS2–)，[2-(4-甲氧基苯基)乙基]黄原酸酯}，[Cu(PPh3)2L2] (2) [L2 = (C6H7OCS2-), 苄基黄原酸酯], [Cu(PPh3)2L3] (3) [L3 = (C5H9OCS2-), (环丁基甲基)黄原酸酯] 和 [Cu(PPh3)2L4] (4) [L4 = (NC13H13NCS2-), N-苄基-N-(4-吡啶基甲基)二硫代氨基甲酸酯]，已通过微量分析、IR、UV/Vis、1H、13C和31P NMR光谱和X射线晶体学合成和表征；已经研究了它们的光致发光行为和分子电导率。CuI 在所有配合物中都具有四坐标扭曲的四面体几何形状。在所研究的 303-363 K 温度范围内，它们都是弱导电的并表现出半导体行为。

  DOI：

  10.1002/ejic.201200307
• 作为产物：
  描述：

  copper(II) nitrate trihydrate 、 三苯基膦 以 甲醇 为溶剂， 反应 0.17h， 生成 双(三苯基膦)硝酸铜(I)
  参考文献：
  名称：

  使用 Cu(I) 催化剂超声辅助合成 1,5-二取代吡唑

  摘要：

  描述了一种新的有效且方便的合成吡唑的方法。采用已报道的方法由取代苯甲醛和氰基乙酸乙酯合成α,β-不饱和氰基酯。以乙醇钠为碱，在 10 mol% Cu(I) 催化剂存在下，在 60 ℃ 超声波照射下，75-90 分钟内以高产率合成 1,5-二取代吡唑，由 α,β-不饱和氰酯和苯肼合成。与传统方法相比，在超声波照射下反应速率大大提高，并且产率有所提高。

  DOI：

  10.14233/ajchem.2020.22432
• 作为试剂：
  描述：

  2-甲基-3-丁炔-2-醇 、 苄基叠氮 在 双(三苯基膦)硝酸铜(I) 作用下， 反应 7.0h， 以95%的产率得到2-(1-benzyl-1H-1,2,3-triazol-4-yl)-2-propanol
  参考文献：
  名称：

  Solvent-free synthesis of 1,4-disubstituted 1,2,3-triazoles using a low amount of Cu(PPh3)2NO3 complex

  摘要：

  我们开发了一种环保且高效的方法，在无溶剂条件下进行有机叠氮化合物与末端炔烃的铜催化环加成反应。该方案使用廉价且易于制备的Cu(PPh3)2NO3复合物作为催化剂。

  DOI：

  10.1039/c0gc00381f

文献信息

• Heterometallic complexes with borole ligands †‡
  作者：Pierre Braunstein、Ulli Englert、Gerhard E. Herberich、Mark Neuschütz、Martin U. Schmidt

  DOI：10.1039/a903846i

  日期：——

  The borole-containing carbonylmetalates [(η-C4H4BPh)Re(CO)3]– ([Re]–) and [(η-C4H4BPh)Fe(CO)2H]– ([Fe]–) were used for the synthesis of heterometallic complexes with Re–Hg, Re–Cu, Re–Ag, Re–Au or Fe–Pt metal–metal bonds, respectively. The complex [Re]–Hg–[Re] 1 was characterized by X-ray diffraction and contains a linear metal chain. In the presence of HgCl2, redistribution reactions were observed, leading to [Re]–Hg–Cl 2 which was independently prepared from [Re]– and an excess of HgCl2. The reaction of [Fe]– with trans-[PtBr2(4-Mepy)2] (4-Mepy = 4-methylpyridine) afforded the trinuclear complex trans-[Pt[Fe]2(4-Mepy)2] 6 which was characterized by X-ray diffraction and contains two hydrido ligands which bridge the Fe–Pt bonds.

  含硼烷的羰基金属酸盐[(η-C4H4BPh)Re(CO)3]⁻（[Re]⁻）和[(η-C4H4BPh)Fe(CO)2H]⁻（[Fe]⁻）分别用于合成了含有Re-Hg、Re-Cu、Re-Ag、Re-Au或Fe-Pt金属-金属键的异金属配合物。配合物[Re]⁻Hg⁻[Re] 1通过X射线衍射进行了表征，并含有一个线性金属链。在存在HgCl2的情况下，观察到了重分布反应，生成了[Re]⁻Hg⁻Cl 2，该化合物也可以从[Re]⁻和过量的HgCl2独立制备。[Fe]⁻与trans-[PtBr2(4-Mepy)2]（4-Mepy = 4-甲基吡啶）的反应生成三核配合物trans-[Pt[Fe]2(4-Mepy)2] 6，该配合物通过X射线衍射进行了表征，并含有两个通过Fe-Pt键桥接的氢化物配体。
• Synthesis and reactivity of bis(diphenylphosphino)amine-bridged heterobimetallic iron–platinum μ-isonitrile and μ-aminocarbyne complexes
  作者：Michael Knorr、Isabelle Jourdain、Ahmed Said Mohamed、Abderrahim Khatyr、Stephan G. Koller、Carsten Strohmann

  DOI：10.1016/j.jorganchem.2014.12.028

  日期：2015.3

  Reaction of [(OC)3Fe(μ-CO)(μ-dppa)Pt(PPh3)] (1) (dppa = bis(diphenylphosphino)amine) with various isonitriles in a 1:1 or 1:2 ratio yields the isonitrile-bridged compounds [(OC)3Fe(μ-CN-R)(μ-dppa)Pt(PPh3)] (2) and [(OC)2(RNC)Fe(μ-CN-R)(μ-dppa)Pt(PPh3)] (3), respectively. However, addition of tert-butylisonitrile to 1 affords the carbonyl-bridged complex [(OC)2(tert-BuNC)Fe(μ-CO)(μ-dppa)Pt(PPh3)] (2g). Upon

  [（OC）3 Fe（μ-CO）（μ-DPPA）Pt（PPh 3）]（1）（DPPA =双（二苯基膦基）胺）与各种异腈以1：1或1：2的比例反应异腈桥接化合物[（OC）3 Fe（μ-CN-R）（μ-DPPA）Pt（PPh 3）]（2）和[（OC）2（RNC）Fe（μ-CN-R）（ μ-DPPA）Pt（PPh 3）]（3）。但是，向1中添加叔丁基异腈可得到羰基桥联的配合物[（OC）2（叔-BuNC）Fe（μ-CO）（μ-DPPA）Pt（PPh 3）]（2g）。经治疗[（OC）3Fe（μ-CN- o-茴香基）（μ-DPPA）Pt（PPh 3）]（2b）与SO 2一起，从其桥接位置追赶μ-CNR配体，得到二氧化硫桥联的化合物[[OC ）2（ø -anisylNC）的Fe（μ-SO 2）（μ-DPPA）的Pt（PPH 3）]（4）。这些化合物转化为μ-氨基碳炔盐[（OC）2（L）Fe μ-CN（R）R'}（μ-DPPA）Pt（PPh
• PROCESS FOR PREPARING A PROPIOLIC ACID OR A DERIVATIVE THEREOF
  申请人：Goossen Lukas J

  公开号：US20140012000A1

  公开（公告）日：2014-01-09

  The invention relates to a process for preparing a propiolic acid or a derivative thereof by reacting a terminal alkyne with carbon dioxide, which comprises performing the reaction in the presence of a base and a copper complex, especially a copper (I) complex having at least one ligand, at least one of the ligands of the copper complex being selected from monodentate ligands which have an aminic or iminic nitrogen atom capable of coordination with copper, and polydentate ligands having at least two atoms or atom groups which are capable of simultaneous coordination with copper and are selected from nitrogen, oxygen, sulfur, phosphorus and carbene carbon.

  该发明涉及一种通过将末端炔烃与二氧化碳反应制备丙炔酸或其衍生物的方法，其中在碱和铜络合物的存在下进行反应，特别是在至少具有一个配体的铜（I）络合物的存在下进行反应，铜络合物的配体中至少有一个被选择自具有能够与铜配位的氨基或亚胺基氮原子的一价配体，以及具有至少两个能够与铜同时配位的原子或原子团的多齿配体，这些原子或原子团被选择自氮、氧、硫、磷和卡宾碳。
• Methods and systems for preparing fused heterocyclic compounds using copper(I) catalysts
  申请人：University of Massachusetts

  公开号：US07473786B1

  公开（公告）日：2009-01-06

  A copper(I)-catalyzed procedure for the synthesis of benzo[b]heterocycles. This protocol can be used to synthesize a variety of 2-arylbenzo[b]furans and indoles in good to excellent yields. This method can tolerate a variety of functional groups, does not require the use of expensive additives and is palladium-free.

  一种铜(I)催化的合成苯并[b]杂环化合物的方法。该方案可用于合成多种2-芳基苯并[b]呋喃和吲哚，收率良好至优秀。此方法能容忍多种官能团，无需使用昂贵添加剂，并且不含钯。
• Synthesis and X-ray crystal structures of metal complexes of three isomeric bibenzodiazines: Discrete and polymeric assemblies
  作者：Christopher M. Fitchett、Peter J. Steel

  DOI：10.1016/j.poly.2008.01.026

  日期：2008.4

  Thirteen complexes of three isomeric bibenzodiazines were prepared and X-ray crystal structures were determined for seven of these. It is shown that 2,2′-biquinazoline prefers to form mononuclear complexes with chelation involving the less hindered nitrogen donors. Complexes of 4,4′-biquinazoline failed to provide suitable crystals for X-ray structure determination. 2,2′-Biquinoxaline is shown to offer

  制备了三种异构体联苯并二嗪的13种配合物，并确定了其中7种的X射线晶体结构。结果表明2,2'-联喹唑啉倾向于与受阻较少的氮供体发生螯合而形成单核络合物。4,4'-联喹唑啉的配合物无法为X射线结构测定提供合适的晶体。显示2,2'-联喹喔啉可提供两种配位模式；在第一种模式中，它使用受阻较少的两个氮原子作为“阶梯线性”桥接配体，而在第二种模式中，它使用受阻性较高的氮螯合至铜（I）中心。稠合苯并环的存在会导致此类配体中杂环配体的π–π堆积更高的倾向。