1-(4Methoxybenzylmercapto)cyclohexane-1-carboxylic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-(4Methoxybenzylmercapto)cyclohexane-1-carboxylic acid
• 英文别名: 1-(carboxy)-1-(4-methoxybenzylthio)cyclohexane；1-[(4-methoxyphenyl)methylsulfanyl]cyclohexane-1-carboxylic acid
• 化学式: C₁₅H₂₀O₃S
• 分子量: 280.388
• InChiKey: FCXWHAKZFUYIBA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  71.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-(4Methoxybenzylmercapto)cyclohexane-1-carboxylic acid 在 氯化亚砜 作用下， 以 DMF (N,N-dimethyl-formamide) 、 甲苯 为溶剂， 反应 0.08h， 生成 1-[(4-Methoxyphenyl)methylsulfanyl]cyclohexane-1-carbonyl chloride
  参考文献：
  名称：

  2- and 2,5-substituted phenylketoenols

  摘要：

  该发明涉及公式(I)中的新型苯基取代的环状酮烯醇，其中Het代表其中一种基团，在其中A、B、D、G、X和Z各自如描述中定义的多种过程和中间体的制备，以及它们作为杀虫剂的用途。

  公开号：

  US06359151B2
• 作为产物：
  描述：

  1-(carboethoxy)-1-(4-methoxybenzylthio)cyclohexane 在 sodium hydroxide 、 lithium hydroxide monohydrate 作用下， 以 四氢呋喃 、 乙醇 、 二氯甲烷 、 水 为溶剂， 生成 1-(4Methoxybenzylmercapto)cyclohexane-1-carboxylic acid
  参考文献：
  名称：

  2-substituted indane-2-mercaptoacetylamide derivatives useful as

  摘要：

  本发明涉及新型的2-取代的茚-2-巯基乙酰胺衍生物，可用作脑啡肽酶和ACE的抑制剂。

  公开号：

  US05428158A1

文献信息

• 3-aryl-4-hydroxy-.DELTA..sup.3 -dihydrothiophenone derivatives
  申请人：Bayer Aktiengesellschaft

  公开号：US05945444A1

  公开（公告）日：1999-08-31

  The present invention relates to novel 3-aryl-4-hydroxy-.DELTA..sup.3 -dihydrothiophenone derivatives of the formula (I) ##STR1## in which A, B, G, S, X, Y, Z and n have the meaning given in the description, to processes for their preparation, to novel intermediates and to the use of the compounds of the formula (I) as agents for controlling pests.

  本发明涉及一种新颖的3-芳基-4-羟基-Δ3-二氢噻吩酮衍生物，其化学式为(I) ##STR1## 其中A、B、G、S、X、Y、Z和n的含义如描述中所述，以及它们的制备方法、新颖的中间体和作为控制害虫的化合物(I)的用途。
• Novel 2-substituted indane-2-mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
  申请人：MERRELL PHARMACEUTICALS INC.

  公开号：EP0534363A2

  公开（公告）日：1993-03-31

  The present invention relates to novel 2-substituted indane-2-mercaptoacetylaminde derivatives which are useful as inhibitors of enkephalinase and ACE.

  本发明涉及新型 2-取代茚满-2-巯基乙酰胺衍生物，可用作脑啡肽酶和 ACE 的抑制剂。
• Arylphenyl-substituted cyclic ketoenols
  申请人：——

  公开号：US20030096806A1

  公开（公告）日：2003-05-22

  The present invention relates to novel arylphenyl-substituted cyclic ketoenols of the formula (I) 1 in which X represents halogen, alkyl, alkoxy, alkenyloxy, alkylthio, alkylsulphinyl, alkylsulphonyl, halogenoalkyl, halogenoalkoxy, halogenoalkenyloxy, nitro, cyano or in each case optionally substituted phenyl, phenoxy, phenylthio, phenylalkoxy or phenylalkylthio, Y represents in each case optionally substituted cycloalkyl, aryl or hetaryl, W represents hydrogen, halogen, alkyl, alkoxy, alkenyloxy, halogenoalkyl, halogenoalkoxy, halogenoalkenyloxy, nitro or cyano, Z represents halogen, alkyl, alkoxy, alkenyloxy, halogenoalkyl, halogenoalkoxy, halogenoalkenyloxy, nitro or cyano, CKE represents one of the groups 2 in which A, B, D, G and Q 1 , S, Q 6 are each as defined in the description, to a plurality of processes for their preparation and to their use as pesticides and herbicides.

  本发明涉及式 (I) 的新型芳基苯基取代环酮烯醇 1 其中 X 代表卤素、烷基、烷氧基、烯氧基、烷硫基、烷基亚磺酰基、烷基磺酰基、卤代烷基、卤代烷氧基、卤代烯氧基、硝基、氰基或在每种情况下任选取代的苯基、苯氧基、苯硫基、苯烷氧基或苯烷基硫基、 Y 在每种情况下代表任选取代的环烷基、芳基或 hetaryl、 W 代表氢、卤素、烷基、烷氧基、烯氧基、卤代烷基、卤代烷氧基、卤代烯氧基、硝基或氰基、 Z 代表卤素、烷基、烷氧基、烯氧基、卤代烷基、卤代烷氧基、卤代烯氧基、硝基或氰基、 CKE 代表以下基团之一 2 其中 A、B、D、G 和 Q 1 ，S、Q 6 均如说明中所定义、 制备它们的多种工艺，以及它们作为杀虫剂和除草剂的用途。
• Arylphenyl-substituted cyclic keto-enols
  申请人：Lieb Folker

  公开号：US20080081807A1

  公开（公告）日：2008-04-03

  The present invention relates to novel arylphenyl-substituted cyclic ketoenols of the formula (I) in which X represents halogen, alkyl, alkoxy, alkenyloxy, alkylthio, alkylsulphinyl, alkylsulphonyl, halogenoalkyl, halogenoalkoxy, halogenoalkenyloxy, nitro, cyano or in each case optionally substituted phenyl, phenoxy, phenylthio, phenylalkoxy or phenylalkylthio, Y represents in each case optionally substituted cycloalkyl, aryl or hetaryl, Z represents hydrogen, halogen, alkyl, alkoxy, alkenyloxy, halogenoalkyl, halogenoalkoxy, halogenoalkenyloxy, nitro or cyano, CKE represents one of the groups in which A, B, D, G and Q 1 to Q 6 are each as defined in the description, to a plurality of processes for their preparation and to their use as pesticides and herbicides.
• ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS
  申请人：Lieb Folker

  公开号：US20100087320A1

  公开（公告）日：2010-04-08

  The present invention relates to novel arylphenyl-substituted cyclic ketoenols of the formula (I) in which X represents halogen, alkyl, alkoxy, alkenyloxy, alkylthio, alkylsulphinyl, alkylsulphonyl, halogenoalkyl, halogenoalkoxy, halogenoalkenyloxy, nitro, cyano or in each case optionally substituted phenyl, phenoxy, phenylthio, phenylalkoxy or phenylalkylthio, Y represents in each case optionally substituted cycloalkyl, aryl or hetaryl, Z represents hydrogen, halogen, alkyl, alkoxy, alkenyloxy, halogenoalkyl, halogenoalkoxy, halogenoalkenyloxy, nitro or cyano, CKE represents one of the groups in which A, B, D, G and Q 1 to Q 6 are each as defined in the description, to a plurality of processes for their preparation and to their use as pesticides and herbicides.