4-benzyl-pentenedioic acid diethyl ester

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-benzyl-pentenedioic acid diethyl ester
• 英文别名: 4-Benzyl-pentendisaeure-diaethylester
• 化学式: C₁₆H₂₀O₄
• 分子量: 276.332
• InChiKey: KUKSSJPMJYYMCE-ZHACJKMWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.53
• 重原子数：
  20.0
• 可旋转键数：
  7.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  52.6
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  4-benzyl-pentenedioic acid diethyl ester 生成 (+/-)-2-benzyl-pentene-(3t)-dioic acid
  参考文献：
  名称：

  Bilateral subclavian steal syndrome

  摘要：

  Background Bilateral atherosclerotic subclavian artery occlusion is rare.Aim To describe the surgical treatment of a patient with symptomatic bilateral subclavian artery occlusion.Methods A midline sternotomy and bilateral aorto-subclavian bypass was performed in a male with upper limb, exercise-induced vertigo.Results Postoperatively symptomatic improvement paralleled an increase in brachial systolic arterial blood pressure readings.Conclusion Bypass grafting is the more durable option for subclavian artery occlusion, as angioplasty with or without stenting is associated with a higher rate of late stenosis.

  DOI：

  10.1007/bf03168943
• 作为产物：
  描述：

  碘乙烷 、 alkaline earth salt of/the/ methylsulfuric acid 在 乙醚 作用下， 生成 4-benzyl-pentenedioic acid diethyl ester
  参考文献：
  名称：

  358.谷氨酸和酯的结构。第五部分：α-苄基和α-苄基-β-甲基-戊二酸

  摘要：

  DOI：

  10.1039/jr9320002434

文献信息

• Thorpe; Wood, Journal of the Chemical Society, 1913, vol. 103, p. 1575
  作者：Thorpe、Wood

  DOI：——

  日期：——
• XVII.—The formation of pyridine derivatives from unsaturated acids: benzyldihydroxypyridine
  作者：S. Ruhemann

  DOI：10.1039/ct8936300259

  日期：——
• Bilateral subclavian steal syndrome
  作者：K. C. Redmond、M. C. Barry、E. Kavanagh、S. Dundon、M. K. O’Malley

  DOI：10.1007/bf03168943

  日期：2002.1

  Background Bilateral atherosclerotic subclavian artery occlusion is rare.Aim To describe the surgical treatment of a patient with symptomatic bilateral subclavian artery occlusion.Methods A midline sternotomy and bilateral aorto-subclavian bypass was performed in a male with upper limb, exercise-induced vertigo.Results Postoperatively symptomatic improvement paralleled an increase in brachial systolic arterial blood pressure readings.Conclusion Bypass grafting is the more durable option for subclavian artery occlusion, as angioplasty with or without stenting is associated with a higher rate of late stenosis.
• 358. The structure of the glutaconic acids and esters. Part V. α-Benzyl- and α-benzyl-β-methyl-glutaconic acids
  作者：G. A. R. Kon、E. M. Watson

  DOI：10.1039/jr9320002434

  日期：——