(+/-)-2-benzyl-pentene-(3t)-dioic acid | 85533-83-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: (+/-)-2-benzyl-pentene-(3t)-dioic acid
• 英文别名: 4-benzyl-pentenedioic acid；(+/-)-2-Benzyl-penten-(3t)-disaeure；4-Benzyl-pentendisaeure；δ-Phenyl-α-butylen-α.γ-dicarbonsaeure；(E)-4-benzylpent-2-enedioic acid
• CAS: 85533-83-1
• 化学式: C₁₂H₁₂O₄
• 分子量: 220.225
• InChiKey: LSQMBLFUWINHJA-VOTSOKGWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (+/-)-2-benzyl-pentene-(3t)-dioic acid 、 苯胺 生成 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Thole; Thorpe, Journal of the Chemical Society, 1911, vol. 99, p. 2205

  摘要：

  DOI：
• 作为产物：
  描述：

  3-苯丙酸乙酯 生成 (+/-)-2-benzyl-pentene-(3t)-dioic acid
  参考文献：
  名称：

  Bilateral subclavian steal syndrome

  摘要：

  Background Bilateral atherosclerotic subclavian artery occlusion is rare.Aim To describe the surgical treatment of a patient with symptomatic bilateral subclavian artery occlusion.Methods A midline sternotomy and bilateral aorto-subclavian bypass was performed in a male with upper limb, exercise-induced vertigo.Results Postoperatively symptomatic improvement paralleled an increase in brachial systolic arterial blood pressure readings.Conclusion Bypass grafting is the more durable option for subclavian artery occlusion, as angioplasty with or without stenting is associated with a higher rate of late stenosis.

  DOI：

  10.1007/bf03168943

文献信息

• Conrad; Guthzeit, Justus Liebigs Annalen der Chemie, 1884, vol. 222, p. 253
  作者：Conrad、Guthzeit

  DOI：——

  日期：——
• Guthzeit; Bolam, Journal fur praktische Chemie (Leipzig 1954), 1896, vol. <2> 54, p. 368
  作者：Guthzeit、Bolam

  DOI：——

  日期：——
• 358. The structure of the glutaconic acids and esters. Part V. α-Benzyl- and α-benzyl-β-methyl-glutaconic acids
  作者：G. A. R. Kon、E. M. Watson

  DOI：10.1039/jr9320002434

  日期：——
• Guthzeit; Laska, Journal fur praktische Chemie (Leipzig 1954), 1898, vol. <2> 58, p. 425
  作者：Guthzeit、Laska

  DOI：——

  日期：——
• Bilateral subclavian steal syndrome
  作者：K. C. Redmond、M. C. Barry、E. Kavanagh、S. Dundon、M. K. O’Malley

  DOI：10.1007/bf03168943

  日期：2002.1

  Background Bilateral atherosclerotic subclavian artery occlusion is rare.Aim To describe the surgical treatment of a patient with symptomatic bilateral subclavian artery occlusion.Methods A midline sternotomy and bilateral aorto-subclavian bypass was performed in a male with upper limb, exercise-induced vertigo.Results Postoperatively symptomatic improvement paralleled an increase in brachial systolic arterial blood pressure readings.Conclusion Bypass grafting is the more durable option for subclavian artery occlusion, as angioplasty with or without stenting is associated with a higher rate of late stenosis.