(2R,3R)-3-hydroxy-3-methyl-2-(p-tolyl)chroman-4-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: (2R,3R)-3-hydroxy-3-methyl-2-(p-tolyl)chroman-4-one
• 英文别名: 3-hydroxy-3-methyl-2-(4-methylphenyl)-2H-chromen-4-one
• 化学式: C₁₇H₁₆O₃
• 分子量: 268.31
• InChiKey: PMUWWDBIGFMHAW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Hair conditioning composition containing flavone derivatives
  申请人：KPSS-Kao Professional Salon Services GmbH

  公开号：EP1683512A1

  公开（公告）日：2006-07-26

  The present invention is related to a conditioning composition for hair comprising flavone derivatives and particularly on enhanced deposition of flavone derivatives onto hair. Accordingly, the compositions comprise at least one conditioning agent, at least one organic solvent, at least one flavone derivative and at least one hydroxycarboxylic and/or dicarboxylic acid and has a pH below 4.5. The conditioning composition of the present invention can be in the form of a shampoo, cleansing - conditioning composition, or in the form of a conditioner used after washing hair with cleansing compositions.

  本发明涉及一种包含黄酮衍生物的头发护理组合物，特别是关于增强黄酮衍生物在头发上的沉积。因此，该组合物包含至少一种调理剂、至少一种有机溶剂、至少一种黄酮衍生物和至少一种羟基羧酸和/或二羧酸，且 pH 值低于 4.5。本发明的护发组合物可以是洗发水、清洁-护发组合物，也可以是用清洁组合物洗发后使用的护发素。
• Method for evaluating or screening hair growth-regulating agent
  申请人：Kao Corporation

  公开号：EP1962090A1

  公开（公告）日：2008-08-27

  The present invention provides a method for evaluating or screening a hair growth-regulating agent which utilizes a readily available animal. The present invention is directed to a method for evaluating or screening a hair growth-regulating agent which comprises subjecting hair follicles of a pig to an organ culture in the presence of a test substance, and evaluating or selecting a substance which promotes or suppresses the growth of the hair follicles.

  本发明提供了一种评估或筛选毛发生长调节剂的方法，该方法利用了一种现成的动物。 本发明涉及一种评估或筛选毛发生长调节剂的方法，该方法包括在存在试验物质的情况下对猪的毛囊进行器官培养，并评估或选择一种促进或抑制毛囊生长的物质。
• Aqueous external preparation for the treatment of scalp
  申请人：Kao Corporation

  公开号：EP1967233A2

  公开（公告）日：2008-09-10

  An aqueous external preparation for scalp, that is directly applied to the scalp to improve the elasticity and luster of newly grown or growing hair without affecting the safety or the feeling of touch of the hair, contains the following components (a) a eucalyptus extract; (b) a blood flow enhancer; (c) an anti-inflammatory agent; (d) an acrylic acid/C10-30 alkyl acrylate copolymer; and (e) ethanol. The blood flow enhancer (b) is preferably selected from the group consisting of swertia japonica extract, vitamin E, nicotinic acid and derivatives thereof. The anti-inflammatory agent (c) is preferably glycyrrhetin or derivatives thereof.

  一种用于头皮的水性外用制剂，可直接涂抹于头皮，在不影响头发的安全性或触感的情况下，改善新长出或正在生长的头发的弹性和光泽，该制剂包含以下成分 (a) 桉树提取物；(b) 血流促进剂；(c) 消炎剂；(d) 丙烯酸/C10-30 丙烯酸烷基共聚物；以及 (e) 乙醇。血流促进剂（b）最好选自獐牙菜提取物、维生素 E、烟酸及其衍生物组成的组。消炎剂（c）最好是甘草亭或其衍生物。
• Composition for hair comprising PCA and PCA ester
  申请人：KPSS-Kao Professional Salon Services GmbH

  公开号：EP2090291A1

  公开（公告）日：2009-08-19

  Present invention relates to a composition for hair comprising pyrrolidon carboxylic acid and/or its salts and its fatty acid esters according to formula wherein R1 is a straight or branched, saturated or unsaturated alkyl chain with 1 to 22 C atoms, phenyl, phenyl alkyl with alkyl chain length of 1 to 4 C atoms, phenyl alkoxy group with alkyl chain length of 1 to 4 C atoms and phenoxy alkyl group with alkyl chain length of 1 to 4 C atoms. Composition of the present invention can be in any form suitable for application onto hair such as in form of a shampoo, cleansing - conditioning composition, or in the form of a conditioner used after washing hair with a cleansing composition. The latter is used either as rinse off or as leave in conditioner.

  本发明涉及一种头发用组合物，该组合物由吡咯烷酮羧酸和/或其盐及其脂肪酸酯按式组成 其中 R1 为 1 至 22 个 C 原子的直链或支链、饱和或不饱和烷基链、苯基、烷基链长度为 1 至 4 个 C 原子的苯基烷基、烷基链长度为 1 至 4 个 C 原子的苯基烷氧基和烷基链长度为 1 至 4 个 C 原子的苯氧基烷基。本发明的组合物可以是任何适合用于头发的形式，如洗发水、清洁-护发组合物，或用清洁组合物洗发后使用的护发素。后者既可用作冲洗剂，也可用作免洗护发素。
• Composition for hair
  申请人：KPSS-Kao Professional Salon Services GmbH

  公开号：EP2184052A1

  公开（公告）日：2010-05-12

  Present invention relates to a composition for hair comprising at least one UV filter and at least one natural oil comprising in its fatty acid composition at least 20% by weight unsaturated fatty acids having 18 C atoms in its molecule and its linoleic acid content is equal or higher than any other unsaturated fatty acid with 18 C atoms in its molecule. Composition of the present invention can be in any form suitable for application onto hair such as in form of a shampoo, cleansing - conditioning composition, or in the form of a conditioner used after washing hair with a cleansing composition. The latter is used either as rinse off or as leave in conditioner.

  本发明涉及一种头发用组合物，该组合物包含至少一种紫外线过滤器和至少一种天然油，在其脂肪酸组成中，至少包含 20% （按重量计）在其分子中具有 18 个 C 原子的不饱和脂肪酸，其亚油酸含量等于或高于在其分子中具有 18 个 C 原子的任何其他不饱和脂肪酸。本发明的组合物可以是任何适合涂抹在头发上的形式，如洗发水、清洁-护发组合物，或用清洁组合物洗发后使用的护发素。后者既可用作冲洗剂，也可用作免洗护发素。