4,5-dimethyl-2-(2H-tetrazol-3-ium-3-yl)-1,3-thiazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4,5-dimethyl-2-(2H-tetrazol-3-ium-3-yl)-1,3-thiazole
• 化学式: C6H8N5S+
• 分子量: 182.23
• InChiKey: PYBJFYDPEWEYMQ-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  86.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• LIPOSOMES COVERED WITH THE EXTRACELLULAR DOMAIN OF THE APO2L/TRAIL PROTEIN
  申请人：Universidad De Zaragoza

  公开号：EP2468260A2

  公开（公告）日：2012-06-27

  The invention relates to the field of biotechnology and medicine. The invention specifically relates to a compound comprising a liposome covered or decorated at least with the extracellular domain of the APO2L/TRAIL protein, and to the use thereof for developing a medicament preferably for the treatment of a cancer or inflammatory or autoimmune diseases, such as rheumatoid arthritis.

  本发明涉及生物技术和医药领域。本发明具体涉及一种化合物，该化合物由至少覆盖或装饰有 APO2L/TRAIL 蛋白胞外结构域的脂质体组成，并涉及使用该化合物开发药物，最好用于治疗癌症或炎症性或自身免疫性疾病，如类风湿性关节炎。
• Liposomes covered with the Extracellular Domain of the APO2L/Trail Protein
  申请人：Anel Bernal Luis Alberto

  公开号：US20120189690A1

  公开（公告）日：2012-07-26

  The invention relates to the field of biotechnology and medicine. The invention specifically relates to a compound comprising a liposome covered or decorated at least with the extracellular domain of the APO2L/TRAIL protein, and to the use thereof far developing a medicament preferably for the treatment of a cancer or inflammatory or autoimmune diseases, such as rheumatoid arthritis.
• US6225074B1
  申请人：——

  公开号：US6225074B1

  公开（公告）日：2001-05-01