1-(2-chloro-6-fluorobenzyl)-5-(2-trifluoromethylphenyl)-1H-1,2,3,4-tetrazole | 1027917-97-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-(2-chloro-6-fluorobenzyl)-5-(2-trifluoromethylphenyl)-1H-1,2,3,4-tetrazole
• 英文别名: 1-[(2-Chloro-6-fluorophenyl)methyl]-5-[2-(trifluoromethyl)phenyl]tetrazole
• CAS: 1027917-97-0
• 化学式: C₁₅H₉ClF₄N₄
• 分子量: 356.71
• InChiKey: FSSQJLVYOFMLHU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  43.6
• 氢给体数：
  0
• 氢受体数：
  7

文献信息

• Use of Benzodiazepine Receptor Ligands For Combating Signs of Ageing
  申请人：Besne Isabelle

  公开号：US20080194620A1

  公开（公告）日：2008-08-14

  The invention relates to the cosmetic use of at least one benzodiazepine peripheral receptor antagonist in a composition containing a physiologically acceptable medium, as an agent for reducing or preventing cutaneous signs of ageing.

  本发明涉及使用至少一种苯二氮平周围受体拮抗剂作为化妆品成分，含有生理上可接受的介质，用作减少或预防皮肤老化迹象的药剂。
• REMEDIES FOR STRESS DISEASES COMPRISING MITOCHONDRIAL BENZODIAZEPINE RECEPTOR ANTAGONISTS
  申请人：ONO PHARMACEUTICAL CO., LTD.

  公开号：EP1438973A1

  公开（公告）日：2004-07-21

  A pharmaceutical composition for the prophylaxis and/or treatment of diseases induced, exacerbated or reignited by stressors comprising the compound of formula (I) wherein all symbols have the same meanings as described in the specification, etc. as an active ingredient.

  一种用于预防和/或治疗由应激源诱发、加重或复燃的疾病的药物组合物，由式 (I) 化合物组成 其中所有符号的含义与说明书中所述的相同等作为活性成分。
• Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists
  申请人：Seko Takuya

  公开号：US20050009812A1

  公开（公告）日：2005-01-13

  A pharmaceutical composition for the prophylaxis and/or treatment of diseases induced, exacerbated or reignited by stressors comprising the compound of formula (I) wherein all symbols have the same meanings as described in the specification, etc. as an active ingredient.