3-[[(2S)-2-amino-3-methyl-3-sulfanylbutanoyl]amino]propanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 肽模拟物
• 英文名称: 3-[[(2S)-2-amino-3-methyl-3-sulfanylbutanoyl]amino]propanoic acid
• 化学式: C₈H₁₆N₂O₃S
• 分子量: 220.29
• InChiKey: ZVFWAPVAPVBNAN-LURJTMIESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.2
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  93.4
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• N-terminal D(-)-penicillamine peptides as aldehyde sequestration agents
  申请人：——

  公开号：US20010041789A1

  公开（公告）日：2001-11-15

  The invention provides a compound of formula I: 1 wherein R 1 -R 3 have any of the values described in the specification; or a salt thereof. The compounds are useful as aldehyde sequestration agents (e.g., in the treatment of alcohol-related diseases). The invention also provides compositions comprising such compounds as well as therapeutic methods comprising their administration.

  该发明提供了一个公式I:1的化合物，其中R1-R3具有规范中描述的任何值；或其盐。这些化合物可用作醛缄合剂（例如，在治疗与酒精相关的疾病中）。该发明还提供了包含这些化合物的组合物，以及包括它们的给药的治疗方法。
• US6686336B2
  申请人：——

  公开号：US6686336B2

  公开（公告）日：2004-02-03
• [EN] N-TERMINAL D(-)-PENICILLAMINE PEPTIDES AS ALDEHYDE SEQUESTRATION AGENTS<br/>[FR] PEPTIDES D(-)-PENICILLAMINE N-TERMINAL UTILISES COMME AGENTS DE SEQUESTRATION D'ALDEHYDE
  申请人：NAGASAWA HERBERT T

  公开号：WO2001058928A1

  公开（公告）日：2001-08-16

  The invention provides a compound of formula (I): wherein R1-R3 have any of the values described in the specification; or a salt thereof. The compounds are useful as aldehyde sequestration agents (e.g., in the treatment of alcohol-related diseases). The invention also provides compositions comprising such compounds as well as therapeutic methods comprising their administration.