4-(1H-[1]benzothieno[3,2-c]pyrazol-3-yl)-N-(2-morpholinoethyl)benzylamine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-(1H-[1]benzothieno[3,2-c]pyrazol-3-yl)-N-(2-morpholinoethyl)benzylamine
• 英文别名: N-[[4-(1H-[1]benzothiolo[3,2-c]pyrazol-3-yl)phenyl]methyl]-2-morpholin-4-ylethanamine
• 化学式: C₂₂H₂₄N₄OS
• 分子量: 392.525
• InChiKey: VENJJPMHBIGVNM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  28
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  81.4
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• SUBSTITUTED 1,4-DIHYDROINDENO[1,2-C]PYRAZOLES AS INHIBITORS OF TYROSINE KINASE
  申请人：BASF AKTIENGESELLSCHAFT

  公开号：EP1165544A1

  公开（公告）日：2002-01-02
• INHIBITORS OF PROTEIN KINASES
  申请人：Knoll GmbH

  公开号：EP1268437A1

  公开（公告）日：2003-01-02
• US6297238B1
  申请人：——

  公开号：US6297238B1

  公开（公告）日：2001-10-02
• [EN] SUBSTITUTED 1,4-DIHYDROINDENO[1,2-C]PYRAZOLES AS INHIBITORS OF TYROSINE KINASE<br/>[FR] 1,4 DIHYDROINDENO[1, 2-C]PYRAZOLES SUBSTITUES UTILISES COMME INHIBITEURS DE LA TYROSINE KINASE
  申请人：BASF AG

  公开号：WO2000059901A1

  公开（公告）日：2000-10-12

  This invention relates to compounds formula (I) and pharmaceutically acceptable salts thereof which are inhibitors of protein kinase activity, to pharmaceutical compositions containing these pyrazoles and to processes for preparing these pyrazoles.
• [EN] INHIBITORS OF PROTEIN KINASES<br/>[FR] INHIBITEURS DE PROTEINES KINASES
  申请人：KNOLL GMBH

  公开号：WO2002030908A1

  公开（公告）日：2002-04-18

  This invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof wherein the variables are as defined in the description. The compounds of formula I are useful as kinase inhibitors.