benzenehexacarboxylic acid monoanhydride

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: benzenehexacarboxylic acid monoanhydride
• 英文别名: 1,3-Dioxo-2-benzofuran-4,5,6,7-tetracarboxylic acid
• 化学式: C₁₂H₄O₁₁
• 分子量: 324.157
• InChiKey: GXAKYQOFVAIUKT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  193
• 氢给体数：
  4
• 氢受体数：
  11

上下游信息

• 上游原料

  中文名称	英文名称	CAS号	化学式	分子量
  苯六甲酸	benzenehexacarboxylic acid	517-60-2	C12H6O12	342.172

反应信息

• 作为产物：
  描述：

  苯六甲酸 在 1-(3-二甲基氨基丙基)-3-乙基碳二亚胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 0.08h， 生成 benzenehexacarboxylic acid monoanhydride
  参考文献：
  名称：

  Formation of Protein Charge Ladders by Acylation of Amino Groups on Proteins

  摘要：

  The values of charge and electrophoretic mobility of a protein are changed upon acylation of its alpha- and Lys epsilon-NH3+ groups. Partial acylation of the amino groups of a protein results in a set of derivatives that is often resolved by capillary electrophoresis into a set of distinct peaks-the "rungs" of a protein charge ladder-that differ incrementally in the number of residues modified. Proteins that have values of MW < 50 kD usually form resolved charge ladders when allowed to react with acetic anhydride, while proteins that have values of MW > 50 kD form broad unresolved peaks. Resolved charge ladders of proteins that have values of MW > 50 kD may be formed using acylating agents that introduce several charges upon acylation of each of their Lys epsilon-NH3+ groups. As an example, L-lactate dehydrogenase (MW = 147 kD) does not form a resolved charge ladder when modified with acetic anhydride. When it is acylated with either 1,2,4-benzenetricarboxylic anhydride, 3, or 1,2,4,5-benzenetetracarboxylic dianhydride, 4, however, it forms charge ladders in which each of the first several pairs of adjacent rungs are separated by approximately 3 or 4 units of charge, respectively. The procedures described in this paper were used to form resolved charge ladders from 25 proteins differing in pI and in MW.

  DOI：

  10.1021/ja9723491

文献信息

• ORGANIC ELECTROLUMINESCENT DEVICE
  申请人：Nippon Steel Chemical Co., Ltd.

  公开号：EP2276085A1

  公开（公告）日：2011-01-19

  Provided are a hole-injecting material for an organic electroluminescent device (organic EL device) exhibiting high luminous efficiency at a low voltage and having greatly improved driving stability, and an organic EL device using the material. The hole-injecting material for an organic EL device is selected from benzenehexacarboxylic acid anhydrides, benzenehexacarboxylic acid imides, or N-substituted benzenehexacarboxylic acid imides. Further, the organic EL device has at least one light-emitting layer and at least one hole-injecting layer between an anode and a cathode arranged opposite to each other, and includes the above-mentioned hole-injecting material for an organic EL device in the hole-injecting layer. The organic EL device may contain a hole-transporting material having an ionization potential (IP) of 6.0 eV or less in the hole-injecting layer or a layer adjacent to the hole-injecting layer.

  本文提供了一种用于有机电致发光器件（有机 EL 器件）的空穴注入材料，该材料在低电压下具有高发光效率，并且大大提高了驱动稳定性，还提供了一种使用该材料的有机 EL 器件。有机电致发光器件的注入孔材料选自苯六羧酸酐、苯六羧酸亚胺或 N-取代苯六羧酸亚胺。进一步地，有机电致发光器件具有至少一个发光层和至少一个位于相对布置的阳极和阴极之间的空穴注入层，并在空穴注入层中包括上述用于有机电致发光器件的空穴注入材料。有机电致发光器件可在空穴注入层或与空穴注入层相邻的层中包含电离电势（IP）为 6.0 eV 或更低的空穴传输材料。
• US8847367B2
  申请人：——

  公开号：US8847367B2

  公开（公告）日：2014-09-30
• [EN] ORGANIC ELECTROLUMINESCENT DEVICE<br/>[FR] DISPOSITIF ÉLECTROLUMINESCENT ORGANIQUE
  申请人：NIPPON STEEL CHEMICAL CO

  公开号：WO2009119249A1

  公开（公告）日：2009-10-01

  　低い電圧で発光効率が高くかつ駆動安定性においても大きく改善された有機エレクトロルミネッセント素子（有機ＥＬ素子）用正孔注入材料及びそれを使用した有機ＥＬ素子を開示する。 　この有機ＥＬ素子用正孔注入材料は、ベンゼンヘキサカルボン酸無水物、ベンゼンヘキサカルボン酸イミド又はベンゼンヘキサカルボン酸イミドのＮ置換体から選ばれる。また、この有機ＥＬ素子は、対向する陽極と陰極の間に、少なくとも１層の発光層と正孔注入層を有し、正孔注入層中に上記有機ＥＬ素子用正孔注入材料を含む。この有機ＥＬ素子は、正孔注入層又はこれに隣接する層にイオン化ポテンシャル（ＩＰ）が６．０ｅＶ以下である正孔輸送性材料を含有することができる。
• Formation of Protein Charge Ladders by Acylation of Amino Groups on Proteins
  作者：Ian J. Colton、Janelle R. Anderson、Jinming Gao、Robert G. Chapman、Lyle Isaacs、George M. Whitesides

  DOI：10.1021/ja9723491

  日期：1997.12.1

  The values of charge and electrophoretic mobility of a protein are changed upon acylation of its alpha- and Lys epsilon-NH3+ groups. Partial acylation of the amino groups of a protein results in a set of derivatives that is often resolved by capillary electrophoresis into a set of distinct peaks-the "rungs" of a protein charge ladder-that differ incrementally in the number of residues modified. Proteins that have values of MW < 50 kD usually form resolved charge ladders when allowed to react with acetic anhydride, while proteins that have values of MW > 50 kD form broad unresolved peaks. Resolved charge ladders of proteins that have values of MW > 50 kD may be formed using acylating agents that introduce several charges upon acylation of each of their Lys epsilon-NH3+ groups. As an example, L-lactate dehydrogenase (MW = 147 kD) does not form a resolved charge ladder when modified with acetic anhydride. When it is acylated with either 1,2,4-benzenetricarboxylic anhydride, 3, or 1,2,4,5-benzenetetracarboxylic dianhydride, 4, however, it forms charge ladders in which each of the first several pairs of adjacent rungs are separated by approximately 3 or 4 units of charge, respectively. The procedures described in this paper were used to form resolved charge ladders from 25 proteins differing in pI and in MW.