3-(4,5-Diphenylimidazol-1-yl)propan-1-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 3-(4,5-Diphenylimidazol-1-yl)propan-1-amine
• 化学式: C₁₈H₁₉N₃
• 分子量: 277.4
• InChiKey: BVKPOMJWOHSWEA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  43.8
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Compounds of the family of 3-alkyl-(4,5-diphenyl-imidazol-1-yl) and their use as soothing agents
  申请人：——

  公开号：US20040162328A1

  公开（公告）日：2004-08-19

  The invention concerns novel compounds of the family of 3-Alkyl-(4,5 diphenyl-imidazol-1-yl), their synthesis method and cosmetic, hygienic or pharmaceutical compositions containing them The invention also concerns the use, in a physiologically acceptable medium, in or for preparing a soothing composition, of at least a compound of the family of 3-Alkyl-(4,5 diphenyl-imidazol-1-yl). The invention further concerns the use, in a physiologically acceptable medium, in or for preparing a composition, a compound of the family of 3-Alkyl-(4,5 diphenyl-imidazol-1-yl), the compound and the composition being designed for soothing skin troubles such as sensitive skins, discomfort, gnawing, itching, irritations, red spots, heat and/or flush sensations, advantageously sensitive and/or irritable and/or reactive and/or allergic symptoms of the skin and/or the scalp and/or mucosa. Finally, the invention concerns a soothing cosmetic treatment using such a composition

  本发明涉及3-烷基-(4,5-二苯基-咪唑-1-基)家族的新化合物，其合成方法以及含有它们的化妆品、卫生或药物组合物。本发明还涉及在生理上可接受的介质中使用3-烷基-(4,5-二苯基-咪唑-1-基)家族的至少一个化合物制备舒缓组合物。本发明还涉及在生理上可接受的介质中使用3-烷基-(4,5-二苯基-咪唑-1-基)家族的化合物制备舒缓皮肤问题的组合物，例如敏感皮肤、不适、痒、刺激、红斑、热和/或潮红感，优选敏感和/或易激和/或反应和/或过敏症状的皮肤和/或头皮和/或粘膜。最后，本发明涉及使用这样的组合物进行舒缓化妆治疗。