5,6,7-Trimethoxy-2-[4-(methylamino)phenyl]chromen-4-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 5,6,7-Trimethoxy-2-[4-(methylamino)phenyl]chromen-4-one
• 化学式: C₁₉H₁₉NO₅
• 分子量: 341.4
• InChiKey: IDNCWCNPIAWFFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  66
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• Chromones and chromone derivatives and uses thereof
  申请人：Yen Mao-Hsiung

  公开号：US20060142211A1

  公开（公告）日：2006-06-29

  The present invention relates to chromones, novel chromone derivatives, and pharmaceutical formulations containing the same and methods of use thereof. Uses of the present invention include, but are not limited to, use for the prevention and treatment of septic shock, organ injury and other disorders. The compounds described herein can be salt forms and also water-soluble compounds.

  本发明涉及香豆素，新型香豆素衍生物，以及含有它们的制药配方和使用方法。本发明的用途包括但不限于预防和治疗败血性休克、器官损伤和其他疾病。所述化合物可以是盐形式和水溶性化合物。
• CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF
  申请人：Jenken Bioscience, Inc.

  公开号：EP1556031A2

  公开（公告）日：2005-07-27
• EP1556031A4
  申请人：——

  公开号：EP1556031A4

  公开（公告）日：2009-03-25
• US8138165B2
  申请人：——

  公开号：US8138165B2

  公开（公告）日：2012-03-20
• [EN] CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF<br/>[FR] CHROMONES ET DERIVES DE CHROMONES, ET UTILISATIONS DE CEUX-CI
  申请人：JENKEN BIOSCIENCES INC

  公开号：WO2004037193A2

  公开（公告）日：2004-05-06

  The present invention relates to chromones, novel chromone derivatives, and pharmaceutical formulations containing the same and methods of use thereof. Uses of the present invention include, but are not limited to, use for the prevention and treatment of septic shock, organ injury and other disorders. The compounds described herein can be salt forms and also water-soluble compounds.