1,1,1,2,2,3,3,4,4-nonafluorotetradecane | 214196-02-8

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: 1,1,1,2,2,3,3,4,4-nonafluorotetradecane
• 英文别名: 1,1,1,2,2,3,3,4,4-nonafluorohexadecane；1-perfluorobutyl-decane；1,1,1,2,2,3,3,4,4-Nonafluorotetradecane
• CAS: 214196-02-8
• 化学式: C₁₄H₂₁F₉
• 分子量: 360.306
• InChiKey: DXAWILAHNRJMEV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.4
• 重原子数：
  23
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  正癸烯 、 1-九氟丁基溴 在 Eosin Y 、 水 、 sodium thiosulfate 作用下， 以 四氢呋喃 、 乙腈 为溶剂， 反应 17.0h， 以61%的产率得到1,1,1,2,2,3,3,4,4-nonafluorotetradecane
  参考文献：
  名称：

  Metal-Free Visible Light Hydroperfluoroalkylation of Unactivated Alkenes Using Perfluoroalkyl Bromides

  摘要：

  Organic dye-catalyzed visible light induced hydroperfluoroalkylation of unactivated alkenes is described. Hydroperfluoroalkylation proceeds selectively and is applicable for various perfluoroalkyl bromide and alkenes including internal alkenes. The reaction mechanism is discussed, and it is shown that the hydrogen source varies with reaction conditions.

  DOI：

  10.1021/acs.orglett.8b03596

文献信息

• LIPID BARRIER REPAIR
  申请人：Novaliq GmbH

  公开号：EP3856124A1

  公开（公告）日：2021-08-04
• TOPICAL SUNSCREEN FORMULATION
  申请人：Novaliq GmbH

  公开号：EP3856128A1

  公开（公告）日：2021-08-04
• [EN] LIPID BARRIER REPAIR<br/>[FR] RÉPARATION DE LA BARRIÈRE LIPIDIQUE
  申请人：NOVALIQ GMBH

  公开号：WO2020064549A1

  公开（公告）日：2020-04-02

  The present disclosure is in the field of ointments which can be useful for the treatment of diseases or conditions associated with lipid barrier damage of the skin. The ointment comprises a semifluorinated alkane and a solid thickening agent, e.g. a wax, a triglyceride, cetyl alcohol, cetyl palmitate or tetradecanol.
• [EN] TOPICAL SUNSCREEN FORMULATION<br/>[FR] FORMULATION D'ÉCRAN SOLAIRE TOPIQUE
  申请人：NOVALIQ GMBH

  公开号：WO2020064556A1

  公开（公告）日：2020-04-02

  The present disclosure relates to topical sunscreen formulations comprising a semifluorinated alkane and a metal oxide selected from titanium dioxide, zinc oxide or mixtures thereof.
• Metal-Free Visible Light Hydroperfluoroalkylation of Unactivated Alkenes Using Perfluoroalkyl Bromides
  作者：Tomoko Yajima、Satsuki Shigenaga

  DOI：10.1021/acs.orglett.8b03596

  日期：2019.1.4

  Organic dye-catalyzed visible light induced hydroperfluoroalkylation of unactivated alkenes is described. Hydroperfluoroalkylation proceeds selectively and is applicable for various perfluoroalkyl bromide and alkenes including internal alkenes. The reaction mechanism is discussed, and it is shown that the hydrogen source varies with reaction conditions.