钙离子载体IV | 126572-74-5

• 物质功能分类: 分析化学 - 分析试剂 - 常用分析试剂
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 钙离子载体IV
• 中文别名: N,N-二环己基-N′,N′-双十八烷基-3-氧杂戊二酰胺；N,N-二环己基-N′,N′-双十八烷基-二甘醇二酰胺
• 英文名称: Calcium ionophore IV
• 英文别名: 2-[2-(dicyclohexylamino)-2-oxoethoxy]-N,N-dioctadecylacetamide
• CAS: 126572-74-5
• 化学式: C₅₂H₁₀₀N₂O₃
• 分子量: 801.4
• InChiKey: CLLKVTAGSOWKHA-UHFFFAOYSA-N

物化性质

• 熔点：
  50-53 °C

计算性质

• 辛醇/水分配系数(LogP)：
  20.4
• 重原子数：
  57
• 可旋转键数：
  40
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  49.8
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 安全说明：
  S22,S24/25
• WGK Germany：
  3

文献信息

• Systems and methods for detecting an optical change indicating the presence of an analyte
  申请人：Case Western Reserve University

  公开号：US10393665B2

  公开（公告）日：2019-08-27

  One aspect of the present disclosure relates to an analyte sensor device. The analyte sensor device can include an optode layer that undergoes an optical change in the presence of an analyte. The analyte sensor device can also include a selectively-permeable membrane encapsulating the optode layer to form a stable membrane that that minimizes fouling of the analyte sensor device. The analyte sensor device can also include a plurality of microparticles that suppress a background physical interference on a detection of the optical change of the optode layer.

  本公开的一个方面涉及一种分析物传感器装置。分析物传感器装置可以包括一个光电极层，在分析物存在的情况下，光电极层会发生光学变化。分析物传感器装置还可以包括封装光电极层的选择性渗透膜，以形成稳定的膜，最大限度地减少分析物传感器装置的堵塞。分析物传感器装置还可以包括多个微颗粒，以抑制背景物理干扰对光极层光学变化的检测。
• Extensible, multimodal sensor fusion platform for remote, proximal terrain sensing
  申请人：Teralytic, Inc.

  公开号：US10866208B2

  公开（公告）日：2020-12-15

  A sensor assembly includes a housing and multiple sensor array segments. A first sensor array segment includes an antenna. A second sensor array segment has a soil temperature sensor, an electrical conductivity (EC) sensor, a moisture sensor, an ion-sensitive field effect transistor (ISFET) nitrate sensor for detecting nitrates in adjacent soil, an ISFET phosphate sensor for detecting phosphates in adjacent soil, an ISFET potassium sensor for detecting potassium in adjacent soil, and an ISFET pH sensor for detecting pH in adjacent soil, and a reference electrode electrically coupled to the first sensor array segment and to the second sensor array segment. The first sensor array segment and the reference electrode can be disposed on opposite sides of the second sensor array segment.

  传感器组件包括一个外壳和多个传感器阵列部分。第一个传感器阵列部分包括一个天线。第二传感器阵列段有一个土壤温度传感器、一个电导率（EC）传感器、一个湿度传感器、一个用于检测邻近土壤中硝酸盐含量的离子敏感场效应晶体管（ISFET）硝酸盐传感器、一个用于检测邻近土壤中磷酸盐含量的离子敏感场效应晶体管磷酸盐传感器、一个用于检测邻近土壤中钾含量的离子敏感场效应晶体管钾传感器和一个用于检测邻近土壤中 pH 值的离子敏感场效应晶体管 pH 传感器，以及一个与第一传感器阵列段和第二传感器阵列段电耦合的参比电极。第一传感器阵列区段和参比电极可布置在第二传感器阵列区段的相对两侧。
• Method and composition for treatment of headache using magnesium
  申请人：——

  公开号：US20010010827A1

  公开（公告）日：2001-08-02

  A method for monitoring ionized Mg 2+ concentrations and ionized Ca 2+ :Mg 2+ ratios in a patient, useful in diagnosing and prognosing disease states including headache, cardiopulmonary bypass surgery, hypertension, abnormal pregnancy, head trauma, and fetal abnormalities is provided as well as a composition and a method of treating a patient with ionized Mg 2+ or ionized Ca 2+ and Mg 2+ . A method of treating headache is provided.

  一种监测电离镁 2&plus； 浓度和离子化 Ca 2&plus； ：Mg 2&plus； 的比率，有助于诊断和预后疾病状态，包括头痛、心肺旁路手术、高血压、异常妊娠、头部创伤和胎儿畸形。 2&plus； 或离子化 Ca 2&plus； 和镁 2&plus； .提供了一种治疗头痛的方法。
• Sliver type autonomous biosensors
  申请人：——

  公开号：US20040180391A1

  公开（公告）日：2004-09-16

  In vivo or in vitro monitoring of chemical and biochemical species (e.g., pH, or glucose levels) in the interstitial fluid of patients or in a sample of a fluid to be analyzed is provided by a probe ( 10, 70, 210, 270 ). For in vivo monitoring, the probe is readily inserted by a minimally invasive method. Optical or electrochemical sensing methods are employed to detect a physical or chemical change, such as pH, color, electrical potential, electric current, or the like, which is indicative of the concentration of the species or chemical property to be detected. Visual observation by the patient may be sufficient to monitor certain biochemicals (e.g., glucose) with this approach. A CAP membrane allows high enzyme loadings, and thus enables use of microminiature probes, and/or diagnosis of low levels of the analyte(s), with sufficient signal-to-noise ratio and low background current.

  探针可在体内或体外监测患者间质或待分析液体样本中的化学和生化物质（如 pH 值或葡萄糖水平） ( 10, 70, 210, 270 ).对于体内监测，探针可通过微创方法轻松插入。采用光学或电化学传感方法来检测物理或化学变化，如 pH 值、颜色、电势、电流等，这表明要检测的物种或化学性质的浓度。使用这种方法，病人的肉眼观察就足以监测某些生化物质（如葡萄糖）。CAP 膜允许高酶负荷，因此可以使用微型探针和/或诊断低水平的分析物，同时具有足够的信噪比和低背景电流。
• Sensor system
  申请人：Rozakis George

  公开号：US20050221276A1

  公开（公告）日：2005-10-06

  A sensor probe suited for implanting into the skin of a person includes a sensor body which may be formed from a polymer which includes 2-hydroxyethyl methacrylate (HEMA). A sensing system is supported by the body. The sensing system exhibits a detectable change when the probe is exposed to the analyte in the fluid. The sensing system may include an enzyme capable of catalyzing a reaction of the analyte to form a reaction product and a dye system which absorbs in the infrared region of the spectrum in response to the reaction product.

  适合植入人体皮肤的传感器探头包括一个传感器主体，该主体可由包括甲基丙烯酸羟乙酯（HEMA）在内的聚合物形成。传感系统由主体支撑。当探针接触到流体中的分析物时，传感系统会显示出可检测到的变化。传感系统可包括一种能催化分析物反应以形成反应产物的酶和一种能在光谱的红外区域吸收反应产物的染料系统。