(E)-5-methyl-3-(4-methylstyryl)-1,2,4-oxadiazole

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-5-methyl-3-(4-methylstyryl)-1,2,4-oxadiazole
• 英文别名: 5-methyl-3-[(E)-2-(4-methylphenyl)ethenyl]-1,2,4-oxadiazole
• 化学式: C₁₂H₁₂N₂O
• 分子量: 200.24
• InChiKey: FFAGTTSTOOLFFF-BQYQJAHWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  38.9
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (E)-5-methyl-3-(4-methylstyryl)-1,2,4-oxadiazole 在 dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer 、 copper diacetate 、 2,2,2-三氟乙醇-d3 作用下， 反应 18.0h， 生成
  参考文献：
  名称：

  铑（III）催化的恶二唑指导的烯基CH活化以合成获得2-酰基氨基和2-氨基吡啶

  摘要：

  我们在此报告Rh（III）催化的恶二唑与炔烃的偶联和2-酰基氨基和2-氨基吡啶的合成的Rh（III）催化的烯基C–H活化协议，这是各种天然产物和带有易于反应的合成药物的重要杂环骨架功能小组。通过简单的溶剂转换，良好的官能团相容性，优异的产物收率和高的区域选择性对氨基进行的选择性保护/脱保护是该反应方案中见证的一些明显的合成特征。

  DOI：

  10.1021/acs.joc.7b01303
• 作为产物：
  描述：

  对甲基苯甲醛 在 羟胺 、 sodium hydride 作用下， 以 四氢呋喃 、 乙醇 、 水 、 mineral oil 为溶剂， 反应 29.5h， 生成 (E)-5-methyl-3-(4-methylstyryl)-1,2,4-oxadiazole
  参考文献：
  名称：

  铑（III）催化的恶二唑指导的烯基CH活化以合成获得2-酰基氨基和2-氨基吡啶

  摘要：

  我们在此报告Rh（III）催化的恶二唑与炔烃的偶联和2-酰基氨基和2-氨基吡啶的合成的Rh（III）催化的烯基C–H活化协议，这是各种天然产物和带有易于反应的合成药物的重要杂环骨架功能小组。通过简单的溶剂转换，良好的官能团相容性，优异的产物收率和高的区域选择性对氨基进行的选择性保护/脱保护是该反应方案中见证的一些明显的合成特征。

  DOI：

  10.1021/acs.joc.7b01303

文献信息

• Composition, Retardation Plate, Liquid-Crystal Display Device, and Method for Producing Retardation Plate
  申请人：Li Yi

  公开号：US20090174844A1

  公开（公告）日：2009-07-09

  A composition comprising at least one liquid-crystal compound and a polymer having at least one group of the following formula: wherein Mp represents a trivalent linking group; L represents a single bond, or a divalent linking group; X represents a substituted or unsubstituted cyclic linking group; Y represents a single bond, or a divalent linking group; Z represents a substituted or unsubstituted cyclic group; n is 1 to 10.

  一种组合物，包括至少一种液晶化合物和至少一种聚合物，该聚合物具有以下公式中的至少一种基团：其中Mp代表三价连接基团；L代表单键或双价连接基团；X代表取代或未取代的环状连接基团；Y代表单键或双价连接基团；Z代表取代或未取代的环状基团；n为1至10。
• Optical film, and polarizing plate and liquid crystal display device using the same
  申请人：Nagai Michio

  公开号：US20070065601A1

  公开（公告）日：2007-03-22

  An optical film comprising an optically anisotropic layer including a liquid crystalline compound, wherein the optically anisotropic layer satisfies the following formulae: Re (450)/ Re (650)<1.25  Formula (1): wherein Re(450) and Re(650) are in-plane retardation values (unit: nm) of the optically anisotropic layer at wavelengths of 450 nm and 650 nm, respectively; 0.09< Re — m (550)/ d Formula (2): wherein Re_m(550) is an in-plane retardation value (unit: nm) of a uniaxial alignment layer in which the director of the liquid crystalline compound is aligned to be parallel in the plane at a wavelength of 550 nm, and d is the thickness of the uniaxial alignment layer (unit: nm).
• Compound ,Composition And Thin Film
  申请人：Takahashi Makoto

  公开号：US20080064879A1

  公开（公告）日：2008-03-13

  A liquid-crystalline compound of the following formula: wherein Y 11 , Y 12 and Y 13 are methine or N; L 1 , L 2 and L 3 are single bond or divalent group; H 1 , H 2 and H 3 are formula (DI-A) or (DI-B); YA 1 , YA 2 , YB 1 and YB 2 are methine or N; XA and XB are O, S, etc.; R 1 , R 2 and R 3 are -(-L 21 -Q 2 ) n1 -L 22 -L 23 -Q 1 ; L 21 is single bond or divalent group; Q 2 is cyclic divalent group; n1 is 0-4; L 22 is —O—, —O—CO—, etc; L 23 is —O—, —S—, etc.; Q 1 is polymerizable group or H.
• Optically-Anisotropic Film and Liquid-Crystal Display Device
  申请人：Ichihashi Mitsuyoshi

  公开号：US20080075892A1

  公开（公告）日：2008-03-27

  A novel optically-anisotropic film is disclosed. The film is formed of a composition comprising at least one discotic liquid-crystal compound having a ratio, α 1, which is a ratio of birefringence at 400 nm to birefringence at 550 nm in a liquid-crystal state, of less than 1.25, in which the molecules of the liquid-crystal compound are fixed in an alignment state at a mean tilt angle ranging from 35 to 85°, wherein its in-plane retardation Re, as measured in a direction normal to a plane of the optically-anisotropic film for 50 nm wavelength light, falls within the range from 60 nm to 220 nm.
• Composition, retardation plate, and liquid-crystal display device
  申请人：Li Yi

  公开号：US20080090027A1

  公开（公告）日：2008-04-17

  A composition comprising at least one liquid-crystal compound and a polymer having at least one group of the following formula (A) as the constitutive unit thereof: wherein Mp represents a trivalent linking group; L represents a single bond, or a bivalent linking group; X represents a substituted or unsubstituted functional group having a cyclic structure.