quercetin-3-O-α-rhamnopyranoside

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: quercetin-3-O-α-rhamnopyranoside
• 英文别名: quercetin 4'-rhamnopyranoside；3,5,7-trihydroxy-2-[3-hydroxy-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyphenyl]chromen-4-one
• 化学式: C₂₁H₂₀O₁₁
• 分子量: 448.383
• InChiKey: ZJIUPYUHTNCJEH-XNFUJFQVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  32
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  186
• 氢给体数：
  7
• 氢受体数：
  11

反应信息

• 作为产物：
  描述：

  quercetin-3,7-di-O-β-D-glucopyranoside-4'-O-α-L-rhamnopyranoside 在 β-glucosidase 作用下， 生成 quercetin-3-O-α-rhamnopyranoside
  参考文献：
  名称：

  Flavonoid constituents and biological screening ofAstragalus bombycinusBoiss.

  摘要：

  Two new flavonoid compounds were isolated from Astragalus bombycinus Boiss. and identified as quercetin-3,7-di-O--glucopyranoside 4-O--rhamnopyranoside and 5,2,4-trihydroxy-flavone-8-C--arabinopyranoside-7-O--glucopyranoside. In addition, apigenin, apigenin-7-O--glucopyranoside, apigenin 7-O-gentobioside, luteolin, luteolin-7-O--glucopyranoside, quercetin-3,7-di-O--glucopyranoside, quercetin-3-O--glucopyranoside-7-O--rhamnopyranoside and daidzein were also isolated and identified. The structure elucidation of the isolated compounds was performed by chromatographic, chemical and spectroscopic methods. Antioxidant and cytotoxic activities were also determined for the four consecutive extracts of the plant.

  DOI：

  10.1080/14786419.2012.701213

文献信息

• Flavonoid constituents and biological screening of<i>Astragalus bombycinus</i>Boiss.
  作者：Lamyaa F. Ibrahim、Mona M. Marzouk、Sameh R. Hussein、Salwa A. Kawashty、Khaled Mahmoud、Nabiel A.M. Saleh

  DOI：10.1080/14786419.2012.701213

  日期：2013.3

  Two new flavonoid compounds were isolated from Astragalus bombycinus Boiss. and identified as quercetin-3,7-di-O--glucopyranoside 4-O--rhamnopyranoside and 5,2,4-trihydroxy-flavone-8-C--arabinopyranoside-7-O--glucopyranoside. In addition, apigenin, apigenin-7-O--glucopyranoside, apigenin 7-O-gentobioside, luteolin, luteolin-7-O--glucopyranoside, quercetin-3,7-di-O--glucopyranoside, quercetin-3-O--glucopyranoside-7-O--rhamnopyranoside and daidzein were also isolated and identified. The structure elucidation of the isolated compounds was performed by chromatographic, chemical and spectroscopic methods. Antioxidant and cytotoxic activities were also determined for the four consecutive extracts of the plant.