trimethyl((Z)-2-(2-methylcyclopentylidene)hexyl)silane

• 分子结构分类: 有机化合物 - 碳氢化合物衍生物
• 英文名称: trimethyl((Z)-2-(2-methylcyclopentylidene)hexyl)silane
• 化学式: C₁₅H₃₀Si
• 分子量: 238.489
• InChiKey: KYNXEXGCTOLYIF-PFONDFGASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.63
• 重原子数：
  16.0
• 可旋转键数：
  5.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为产物：
  描述：

  1-十一碳烯-6-炔 、 氯甲基三甲基硅烷 在 正丁基锂 、 二氯二茂锆 、 lithium diisopropyl amide 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 生成 trimethyl((Z)-2-(2-methylcyclopentylidene)hexyl)silane 、 trimethyl(2-((E)-2-pentylidenecyclopentyl)ethyl)silane
  参考文献：
  名称：

  Ring expansion of 5- to 6-member zirconacycles by carbenoid insertion

  摘要：

  A wide range of carbenoids (1-lithio-1-halo species), including those with alpha-SiR3, OEt, SPh, SO2Ph, P(O)(OEt)(2), and CN substituents, insert into 5-member zirconacycles (saturated and unsaturated, mono- and bi-cyclic) to afford functionalized 6-member zirconacycles. 1-Lithio-1-haloalkenes insert to afford 6-member zirconacycles with an alkylidene substituent next to the metal. Unexpected double insertion of some carbenoids, and evidence for endocylic beta-hydride transfer processes provide additional mechanistic interest. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2003.09.056

文献信息

• Ring expansion of 5- to 6-member zirconacycles by carbenoid insertion
  作者：Sally Dixon、Shaun M. Fillery、Aleksandra Kasatkin、David Norton、Emma Thomas、Richard J. Whitby

  DOI：10.1016/j.tet.2003.09.056

  日期：2004.2

  A wide range of carbenoids (1-lithio-1-halo species), including those with alpha-SiR3, OEt, SPh, SO2Ph, P(O)(OEt)(2), and CN substituents, insert into 5-member zirconacycles (saturated and unsaturated, mono- and bi-cyclic) to afford functionalized 6-member zirconacycles. 1-Lithio-1-haloalkenes insert to afford 6-member zirconacycles with an alkylidene substituent next to the metal. Unexpected double insertion of some carbenoids, and evidence for endocylic beta-hydride transfer processes provide additional mechanistic interest. (C) 2003 Elsevier Ltd. All rights reserved.