[3-(3-Chlorophenyl)-1,2,4-oxadiazol-5-yl]methanamine | 944901-69-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: [3-(3-Chlorophenyl)-1,2,4-oxadiazol-5-yl]methanamine
• CAS: 944901-69-3
• 化学式: C₉H₈ClN₃O
• mdl: MFCD10034826
• 分子量: 209.63
• InChiKey: RNPITVFPXBNOFU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.111
• 拓扑面积：
  64.9
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Aminoalkyl-pyrazinones and-pyridones as thrombin inhibitors
  申请人：Feurer Achim

  公开号：US20070099927A1

  公开（公告）日：2007-05-03

  The invention relates to compounds of formula (I) wherein A, B, X, R 1 , R 2 , G, R 3 , D and E have the meaning as cited in the description and the claims. Said compounds are useful as coagulants. The invention also relates to the production and use thereof as medicament.

  本发明涉及式(I)的化合物，其中A，B，X，R1，R2，G，R3，D和E的含义如描述和权利要求中所述。所述化合物可用作凝血剂。本发明还涉及其制备和用作药物的用途。
• [EN] AMINOALKYL-PYRAZINONES AND -PYRIDONES AS THROMBIN INHIBITORS<br/>[FR] AMINOALKYL-PYRAZINONES ET AMINOALKYL-PYRIDONES UTILISEES COMME INHIBITEURS DE THROMBINE
  申请人：GRAFFINITY PHARMACEUTICALS AG

  公开号：WO2005040137A1

  公开（公告）日：2005-05-06

  The invention relates to compounds of formula (1) wherein A, B, X, R<1>, R<2> , G, R< 3> , D and E have the meaning as cited in the description and the claims. Said compounds are useful as coagulants. The invention also relates to the production and use thereof as medicament.