钠离子载体I | 61183-76-4

• 物质功能分类: 分析化学 - 分析试剂 - 常用分析试剂
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 钠离子载体I
• 英文名称: Sodium ionophore I
• 英文别名: 2-[2,2-bis[[2-[heptyl(methyl)amino]-2-oxoethoxy]methyl]butoxy]-N-heptyl-N-methylacetamide
• CAS: 61183-76-4
• 化学式: C₃₆H₇₁N₃O₆
• 分子量: 642.0
• InChiKey: PMECOBBGCPFYPP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8
• 重原子数：
  45
• 可旋转键数：
  31
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.916
• 拓扑面积：
  88.6
• 氢给体数：
  0
• 氢受体数：
  6

安全信息

• 安全说明：
  S23,S24/25
• WGK Germany：
  3

文献信息

• Microsphere optical ion sensors based on doped silica gel templates
  申请人：Bakker Eric

  公开号：US20060240560A1

  公开（公告）日：2006-10-26

  A sensor for determining the concentration of a target ion in a liquid sample having a particulate silica doped with: an ionophore capable of binding the target ion; and an indicator capable of producing a detectable signal in response to binding by the ionophore of the target ion. The detectable signal is related to the target ion concentration in the liquid sample.

  一种用于测定液体样品中目标离子浓度的传感器，其中包含掺杂有颗粒状的二氧化硅，其中包含：能够结合目标离子的离子载体；以及能够在离子载体结合目标离子的响应下产生可检测信号的指示剂。可检测信号与液体样品中目标离子的浓度相关。
• ION-SENSITIVE FILM, A PROCESS FOR PRODUCING THE SAME, AND ION SENSOR
  申请人：TERUMO KABUSHIKI KAISHA

  公开号：EP0411127A1

  公开（公告）日：1991-02-06

  The invention provides an ion-sensitive film (6) comprising a mixture layer of a redox material that exhibits oxidative and reductive functions and a polymer that includes an ion carrier substance. The invention further provides a method of producing the ion-sensitive film (6) and an ion sensor using the same. The ion-sensitive film (6) makes it possible to obtain an ion sensor that exhibits excellent durability. preservation stability and sensor characteristics.

  本发明提供了一种离子敏感薄膜 (6)，该薄膜由具有氧化和还原功能的氧化还原材料和包括离子载体物质的聚合物的混合物层组成。本发明进一步提供了一种生产离子敏感薄膜（6）的方法和使用该薄膜的离子传感器。该离子敏感薄膜（6）使获得具有出色的耐久性、保存稳定性和传感器特性的离子传感器成为可能。
• POTENTIOMETRIC SENSOR FOR THE QUANTITATIVE DETERMINATION OF SODIUM CONCENTRATION AND CREATININE CONCENTRATION
  申请人：Medizinische Universität Innsbruck

  公开号：EP3388825A1

  公开（公告）日：2018-10-17

  The present invention relates to a single-use test-strip for the quantitative determination of sodium concentration and creatinine concentration and for the subsequent determination of their ratio, and to a non-invasive point-of-care (POC) device for detecting sodium depletion and/or sodium overload in a patient's body. Furthermore, the present invention relates to a method for simultaneously and quantitatively determining sodium concentration and creatinine concentration in a patient's urine sample and to a method of detecting sodium depletion and/or sodium overload in a patient's body.

  本发明涉及一种用于定量测定钠浓度和肌酐浓度并随后测定其比率的一次性试纸，以及一种用于检测患者体内钠耗竭和/或钠超负荷的非侵入性护理点（POC）设备。此外，本发明还涉及一种同时定量测定患者尿样中钠浓度和肌酐浓度的方法，以及一种检测患者体内钠耗竭和/或钠超负荷的方法。
• MEANS FOR THE QUANTITATIVE DETERMINATION OF AN ANALYTE CONCENTRATION IN A PATIENT'S URINE SAMPLE
  申请人：Fuhrmann, Gerda Laura

  公开号：EP3537153A1

  公开（公告）日：2019-09-11

  The present invention relates to a single-use monoanalytical test-strip for the quantitative determination of an analyte in a patient's urine sample, and to a non-invasive point-of-care (POC) device for detecting deficiency and/or overload of an analyte in a patient's body. Furthermore, the present invention relates to a method for quantitatively determining the concentration of an analyte in a patient's urine sample and to a method of detecting deficiency and/or overload of an analyte in a patient's body. The test-strip comprises a substrate which either is electrically insulating or which has an electrically insulating layer applied thereon,- an electrode assembly applied on said substrate or on said electrically insulating layer, if present; and said electrode assembly comprises at least- one analyte-selective working electrode;- one reference electrode for said analyte-selective working electrode and an interface for electrically connecting said electrode assembly to a read out-meter device. Analytes are anions selected from halides, phopshates and sulfates or cations of alkali metals, of alkaline earth metals or of other metals.

  本发明涉及一种用于定量测定患者尿样中分析物的一次性单分析试纸，以及一种用于检测患者体内分析物缺乏和/或过量的非侵入性护理点（POC）设备。此外，本发明还涉及一种定量测定患者尿样中分析物浓度的方法，以及一种检测患者体内分析物缺乏和/或过量的方法。检测条包括一个基板，该基板是电绝缘的，或者在其上涂有电绝缘层；- 一个电极组件，如果有的话，涂在所述基板上或所述电绝缘层上；所述电极组件包括至少--一个分析物选择性工作电极；--一个用于所述分析物选择性工作电极的参比电极，以及一个用于将所述电极组件电连接到读出计装置的接口。分析物为阴离子，选自卤化物、磷酸盐和硫酸盐或碱金属、碱土金属或其他金属的阳离子。
• Systems and methods for detecting an optical change indicating the presence of an analyte
  申请人：Case Western Reserve University

  公开号：US10393665B2

  公开（公告）日：2019-08-27

  One aspect of the present disclosure relates to an analyte sensor device. The analyte sensor device can include an optode layer that undergoes an optical change in the presence of an analyte. The analyte sensor device can also include a selectively-permeable membrane encapsulating the optode layer to form a stable membrane that that minimizes fouling of the analyte sensor device. The analyte sensor device can also include a plurality of microparticles that suppress a background physical interference on a detection of the optical change of the optode layer.

  本公开的一个方面涉及一种分析物传感器装置。分析物传感器装置可以包括一个光电极层，在分析物存在的情况下，光电极层会发生光学变化。分析物传感器装置还可以包括封装光电极层的选择性渗透膜，以形成稳定的膜，最大限度地减少分析物传感器装置的堵塞。分析物传感器装置还可以包括多个微颗粒，以抑制背景物理干扰对光极层光学变化的检测。