Reactions of fluoroalkyl-containing bis-β-diketones with hydrazine and hydroxylamine
摘要:
Polyfluoroalkyl-containing bispyrazoles, bis(5-hydroxy-Delta(2)-isoxazolines), and bisisoxazoles were synthesized for the first time by reactions of polyfluoroalkyl-containing bis-beta-diketones with hydrazine, phenylhydrazine, and hydroxylamine, respectively.
is reported that occurs by the three-component coupling of environmentally friendly and large-tonnage industrial feedstock 2-bromo-3,3,3-trifluoropropene (BTP), aldehydes, and sulfonylhydrazides. This highly regioselective three-component reaction is metal-free, catalyst-free, and operationally simple and features mild conditions, a broad substrate scope, high yields, and valuable functional group