1-(diisopropylsilyl)-4-methyl-1-hexyne

• 分子结构分类: 有机化合物 - 碳氢化合物衍生物
• 英文名称: 1-(diisopropylsilyl)-4-methyl-1-hexyne
• 英文别名: 4-Methylhex-1-ynyl-di(propan-2-yl)silane；4-methylhex-1-ynyl-di(propan-2-yl)silane
• 化学式: C₁₃H₂₆Si
• 分子量: 210.435
• InChiKey: TXCPQCQDUHVKOL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.01
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  苯硅烷 、 1-(diisopropylsilyl)-4-methyl-1-hexyne 在 di(bis(η(5)-trimethylsilylcyclopentadienyl)-μ-methylyttrium) 作用下， 以 环己烷 为溶剂， 反应 20.0h， 以82%的产率得到(Z)-1-(diisopropylsilyl)-4-methyl-1-(phenylsilyl)-1-hexene
  参考文献：
  名称：

  Hydrosilylation of alkynylsilanes utilizing organolanthanide and Group 3 metallocene complexes

  摘要：

  The organolanthanide- and Group 3 metallocene-catalyzed hydrosilylation of alkynylsilanes has been found to provide (Z)-1,1-bis(silyl)alkenes. In particular, Cp-2*YMeTHF (1), [(Cp2YMe)-Y-TMS](2) (2), and [(Cp2LuMe)-Lu-TMS](2) (3) were shown to be regioselective for the hydrosilylation of various alkynylsilanes (Fig. 1). The process was evaluated for diverse substitution patterns and functional groups on the pendant alkyl chain. Silyl ethers and halogens are stable to the catalytic process, affording excellent chemo- and regioselectivities. Competition between 'aryl-directed' and 'silyl-directed' processes was observed upon hydrosilylation of (phenylethynyl)dimethylsilane. (C) 2002 Published by Elsevier Science B.V.

  DOI：

  10.1016/s0022-328x(01)01483-8
• 作为产物：
  描述：

  4-甲基-1-己炔 、 二异丙基氯代硅烷 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 0.75h， 以56%的产率得到1-(diisopropylsilyl)-4-methyl-1-hexyne
  参考文献：
  名称：

  Hydrosilylation of alkynylsilanes utilizing organolanthanide and Group 3 metallocene complexes

  摘要：

  The organolanthanide- and Group 3 metallocene-catalyzed hydrosilylation of alkynylsilanes has been found to provide (Z)-1,1-bis(silyl)alkenes. In particular, Cp-2*YMeTHF (1), [(Cp2YMe)-Y-TMS](2) (2), and [(Cp2LuMe)-Lu-TMS](2) (3) were shown to be regioselective for the hydrosilylation of various alkynylsilanes (Fig. 1). The process was evaluated for diverse substitution patterns and functional groups on the pendant alkyl chain. Silyl ethers and halogens are stable to the catalytic process, affording excellent chemo- and regioselectivities. Competition between 'aryl-directed' and 'silyl-directed' processes was observed upon hydrosilylation of (phenylethynyl)dimethylsilane. (C) 2002 Published by Elsevier Science B.V.

  DOI：

  10.1016/s0022-328x(01)01483-8

文献信息

• Hydrosilylation of alkynylsilanes utilizing organolanthanide and Group 3 metallocene complexes
  作者：Gary A. Molander、Jan Antoinette C. Romero、Christopher P. Corrette

  DOI：10.1016/s0022-328x(01)01483-8

  日期：2002.3

  The organolanthanide- and Group 3 metallocene-catalyzed hydrosilylation of alkynylsilanes has been found to provide (Z)-1,1-bis(silyl)alkenes. In particular, Cp-2*YMeTHF (1), [(Cp2YMe)-Y-TMS](2) (2), and [(Cp2LuMe)-Lu-TMS](2) (3) were shown to be regioselective for the hydrosilylation of various alkynylsilanes (Fig. 1). The process was evaluated for diverse substitution patterns and functional groups on the pendant alkyl chain. Silyl ethers and halogens are stable to the catalytic process, affording excellent chemo- and regioselectivities. Competition between 'aryl-directed' and 'silyl-directed' processes was observed upon hydrosilylation of (phenylethynyl)dimethylsilane. (C) 2002 Published by Elsevier Science B.V.