ethyl 2-(2',3',4',5'-tetraethyl-1'-cyclopentadienyl)ethanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: ethyl 2-(2',3',4',5'-tetraethyl-1'-cyclopentadienyl)ethanoate
• 英文别名: 2-(2',3',4',5'-Tetraethylcyclopentadienyl)-acetic acid ethyl ester；ethyl 2-(2,3,4,5-tetraethylcyclopenta-2,4-dien-1-yl)acetate
• 化学式: C₁₇H₂₈O₂
• 分子量: 264.408
• InChiKey: NHMMRSFUAJVCJX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  顺式-3-碘丙烯酸乙酯 、 alkaline earth salt of/the/ methylsulfuric acid 在 copper(l) chloride 作用下， 以 四氢呋喃 为溶剂， 反应 0.25h， 以57%的产率得到ethyl 2-(2',3',4',5'-tetraethyl-1'-cyclopentadienyl)ethanoate
  参考文献：
  名称：

  Reaction of Zirconacycles with 3-Iodopropenoates and 3-Iodocycloenones in the Presence of CuCl:  A New Pathway for the Formation of Cyclopentadienes and Spirocyclic Compounds

  摘要：

  Formation of cyclic compounds from zirconacycles has been performed by a combination of Michael addition and coupling with an alkenyl iodide moiety in the presence of a stoichiometric amount of CuCl. The reaction of 3-iodopropenoates with various zirconacyclopentadienes in the presence of a stoichiometric amount of CuCl afforded penta- and hexasubstituted cyclopentadienes. The reaction of 3-iodocycloenones with zirconacyclopentadienes, zirconacyclopentenes, or zirconacyclopentanes gave spirocyclic compounds in good yields.

  DOI：

  10.1021/jo9905975

文献信息

• Iron(II)-Catalyzed Asymmetric Hydrosilylation of Acetophenone
  作者：Michelle Flückiger、Antonio Togni

  DOI：10.1002/ejoc.201100550

  日期：2011.8

  pentasubstituted cyclopentadiene tethered to a stereogenic diamine unit have been prepared and used in the iron-catalyzed enantioselective hydrosilylation of acetophenone. Catalytically active species have been generated in situ starting from various sources of iron. Fe(acac)2 was the catalyst precursor of choice, whereas other simple FeII or FeIII compounds resulted in significantly lower or no catalytic

  已经制备了四种新的配体，其中含有与立体二胺单元相连的五取代环戊二烯，并用于铁催化的苯乙酮的对映选择性氢化硅烷化。催化活性物质已从各种铁源开始原位生成。Fe(acac)2 是首选的催化剂前体，而其他简单的 FeII 或 FeIII 化合物导致催化活性显着降低或没有催化活性。在室温下使用 4 mol-% Fe 获得定量转化率。和苯基硅烷作为还原剂。在这些条件下，配体 4 提供了 37% ee 的对映选择性。迄今为止，分离含有配体 3-6 的单组分 Fe 配合物的尝试都失败了。
• 1,1-Cycloaddition of zirconacyclopentadienes to propynoates
  作者：Tamotsu Takahashi、Chanjuan Xi、Martin Kotora

  DOI：10.1039/a704740a

  日期：——

  Zinconacyclopentadienes react with propynoates in a 1,1-cycloaddition manner to give pentasubstituted cyclopentadiene derivatives in high yields.

  锌碳环戊二烯与丙炔酸盐以 1,1-Cycloaddition 方式发生反应，生成高产率的五取代环戊二烯衍生物。
• Halogen-dependent coupling reaction of alkynes with (Z)-3-halopropenoates catalyzed by nickel
  作者：Martin Kotora、Masanori Ishikawa、Fu-Yu Tsai、Tamotsu Takahashi

  DOI：10.1016/s0040-4020(99)00182-9

  日期：1999.4

  Ni-catalyzed coupling reaction of alkynes with (Z)-3-halopropenoates depended on the halogen of halopropenoates. The reaction with (Z)-3-bromopropenoate afforded cyclopentadienes and the reaction with Q-3-iodopropenoates gave pyrones. (C) 1999 Elsevier Science Ltd. All rights reserved.
• Cross coupling-conjugate addition reaction of zirconacyclopentadienes with 3-iodopropenoates
  作者：Martin Kotora、Chanjuan Xi、Tamotsu Takahashi

  DOI：10.1016/s0040-4039(98)00762-x

  日期：1998.6

  Copper-mediated reaction of zirconacyclopentadienes with iodopropenoates afforded penta- and hexasubstituted cyclopentadienes. (C) 1998 Elsevier Science Ltd. All rights reserved.